Thioredoxin-interacting Protein Mediates High Glucose-induced Reactive Oxygen Species Generation by Mitochondria and the NADPH Oxidase, Nox4, in Mesangial Cells

Mitochondrial membrane potential probes and the proton gradient: a practical usage guide

(2011) Seth W. Perry et al.   BIOTECHNIQUES

Modulation of Nrf2 expression alters high glucose-induced oxidative stress and antioxidant gene expression in mouse mesangial cells

(2011) Hang Li et al.   CELLULAR SIGNALLING

Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the Nox4 promoter

(2011) Srikanth Pendyala et al.   FREE RADICAL BIOLOGY AND MEDICINE

Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4

(2011) Netanya Y. Spencer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury

(2011) Jun Yoshioka et al.   JOURNAL OF CLINICAL INVESTIGATION

EGFR Signaling Promotes TGF -Dependent Renal Fibrosis

(2011) J. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingosine Kinase-1 Pathway Mediates High Glucose-Induced Fibronectin Expression in Glomerular Mesangial Cells

(2011) Tian Lan et al.   MOLECULAR ENDOCRINOLOGY

The Role of the p38 MAPK Signaling Pathway in High Glucose-Induced Epithelial-Mesenchymal Transition of Cultured Human Renal Tubular Epithelial Cells

(2011) Zhi-Mei Lv et al.   PLoS One

Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-κB in human aortic smooth muscle cells

(2010) Adrian Manea et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ

(2010) Balu K. Chacko et al.   BIOCHEMICAL JOURNAL

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes

(2010) Jianmin Li et al.   DIABETES

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1

(2010) Isabel Diebold et al.   MOLECULAR BIOLOGY OF THE CELL

Oxidative stress in early diabetic nephropathy: fueling the fire

(2010) Dhruv K. Singh et al.   Nature Reviews Endocrinology

Endothelial pro-atherosclerotic response to extracellular diabetic-like environment: Possible role of thioredoxin-interacting protein

(2010) T. Zitman-Gal et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

High β-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice

(2009) Elodie Masson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

(2009) Xiaonan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The roles of ASK family proteins in stress responses and diseases

(2009) Kazuki Hattori et al.   Cell Communication and Signaling

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid-Induced ER Stress-Mediated  -Cell Death

(2009) J. Chen et al.   DIABETES

Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells

(2009) Hyunjoo Cha-Molstad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-independent Regulation of Metabolism by the α-Arrestin Proteins

(2009) Parth Patwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein

(2009) Geetu Saxena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathophysiology of Diabetic Nephropathy: Involvement of Multifaceted Signalling Mechanism

(2009) Pitchai Balakumar et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Reduction of Renal Superoxide Dismutase in Progressive Diabetic Nephropathy

(2009) H. Fujita et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Subcellular localization of Nox4 and regulation in diabetes

(2009) K. Block et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AP-1–Dependent Transcriptional Regulation of NADPH Oxidase in Human Aortic Smooth Muscle Cells

(2008) Adrian Manea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

(2008) C.-L. Chen et al.   BLOOD

Thioredoxin-Interacting Protein: A Critical Link Between Glucose Toxicity and  -Cell Apoptosis

(2008) J. Chen et al.   DIABETES

Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes

(2008) J. M. Forbes et al.   DIABETES

Diabetic Nephropathy: Mechanisms of Renal Disease Progression

(2008) Yashpal S. Kanwar et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

(2008) Junqin Chen et al.   FASEB JOURNAL

Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F

(2008) Li Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes

(2008) Xiaoqing He et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

NOX enzymes and diabetic complications

(2008) Tomoko Kakehi et al.   Seminars in Immunopathology

The pathogenesis of diabetic nephropathy

(2008) Suma Dronavalli et al.   Nature clinical practice. Endocrinology & metabolism