Regulating autophagy facilitated therapeutic efficacy of the sonic Hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS production
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Title
Regulating autophagy facilitated therapeutic efficacy of the sonic Hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS production
Authors
Keywords
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Journal
Cell Death & Disease
Volume 10, Issue 9, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-08-19
DOI
10.1038/s41419-019-1840-6
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Note: Only part of the references are listed.- GLI1 promotes cancer stemness through intracellular signaling pathway PI3K/Akt/NFκB in colorectal adenocarcinoma
- (2018) Zhaoting Yang et al. EXPERIMENTAL CELL RESEARCH
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- (2017) Brigitte Dréno et al. LANCET ONCOLOGY
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- (2017) Klara Mosterd LANCET ONCOLOGY
- Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma
- (2017) Masaya Yotsukura et al. LUNG CANCER
- Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer
- (2017) Nadia B. Hassounah et al. MOLECULAR CANCER RESEARCH
- Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion's disease in Peru
- (2017) Maria J. Pons et al. PLoS Neglected Tropical Diseases
- Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non–Small Cell Lung Cancer
- (2017) Xuyao Zhang et al. Cancer Immunology Research
- Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer
- (2017) Zhaoyun Liu et al. PLoS One
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- (2016) Daniel J Klionsky et al. Autophagy
- AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells
- (2016) Ji Eun Jang et al. CLINICAL CANCER RESEARCH
- Afatinib: A Review in Advanced Non-Small Cell Lung Cancer
- (2016) Gillian M. Keating Targeted Oncology
- The Hedgehog Signaling Networks in Lung Cancer: The Mechanisms and Roles in Tumor Progression and Implications for Cancer Therapy
- (2016) Yoshinori Abe et al. Biomed Research International
- Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia
- (2015) Xian Zeng et al. Autophagy
- Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
- (2015) R. J. Molenaar et al. CANCER RESEARCH
- Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells
- (2015) Verline Justilien et al. CLINICAL CANCER RESEARCH
- Efficacy of Hedgehog Pathway Inhibitors in Basal Cell Carcinoma
- (2015) N. Basset-Seguin et al. MOLECULAR CANCER THERAPEUTICS
- A novel therapeutic approach against B-cell non-Hodgkin’s lymphoma through co-inhibition of Hedgehog signaling pathway and autophagy
- (2015) Jiajun Fan et al. TUMOR BIOLOGY
- Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer
- (2014) L. Huang et al. CLINICAL CANCER RESEARCH
- Pilot Clinical Trial of Hedgehog Pathway Inhibitor GDC-0449 (Vismodegib) in Combination with Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma
- (2014) E. J. Kim et al. CLINICAL CANCER RESEARCH
- The effects of sonic hedgehog signaling pathway components on non-small-cell lung cancer progression and clinical outcome
- (2014) Jinwook Hwang et al. World Journal of Surgical Oncology
- Expression of the GLI family genes is associated with tumor progression in advanced lung adenocarcinoma
- (2014) Masashi Ishikawa et al. World Journal of Surgical Oncology
- Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells
- (2014) Y Sun et al. Cell Death & Disease
- Hedgehog signaling pathway regulates autophagy in human hepatocellular carcinoma cells
- (2013) Ying Wang et al. HEPATOLOGY
- Inhibition of the Hedgehog pathway induces autophagy in pancreatic ductal adenocarcinoma cells
- (2013) YONGHUA XU et al. ONCOLOGY REPORTS
- The Hedgehog processing pathway is required for NSCLC growth and survival
- (2012) J Rodriguez-Blanco et al. ONCOGENE
- The Hedgehog signalling pathway regulates autophagy
- (2012) Maria Jimenez-Sanchez et al. Nature Communications
- There is more to autophagy than induction
- (2011) Daniel J Klionsky et al. Autophagy
- The multiple roles of autophagy in cancer
- (2011) M. T. Rosenfeldt et al. CARCINOGENESIS
- Feedback on Fat: p62-mTORC1-Autophagy Connections
- (2011) Jorge Moscat et al. CELL
- Autophagosomes and human diseases
- (2011) Isabelle Beau et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Hedgehog Signaling Antagonist GDC-0449 (Vismodegib) Inhibits Pancreatic Cancer Stem Cell Characteristics: Molecular Mechanisms
- (2011) Brahma N. Singh et al. PLoS One
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