Perfluorooctane Sulfonate (PFOS) Produces Dopaminergic Neuropathology in Caenorhabditis elegans

Phospholipid Levels Predict the Tissue Distribution of Poly- and Perfluoroalkyl Substances in a Marine Mammal

(2019) Clifton Dassuncao et al.   Environmental Science & Technology Letters

Developmental exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) selectively decreases brain dopamine levels in Northern leopard frogs

(2019) Rachel M. Foguth et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

β-Cyclodextrin Reverses Binding of Perfluorooctanoic Acid to Human Serum Albumin

(2018) Mary Jo Weiss-Errico et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) – A comparison with lysosomotropic drugs

(2018) Diana Sanchez Garcia et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Coencapsulation of cyclodextrins into poly(anhydride) nanoparticles to improve the oral administration of glibenclamide. A screening on C. elegans

(2018) David Lucio et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Caenorhabditis elegans as a model system for target identification and drug screening against neurodegenerative diseases

(2018) Liang Ma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A short review on human exposure to and tissue distribution of per- and polyfluoroalkyl substances (PFASs)

(2018) Jun-Meng Jian et al.   SCIENCE OF THE TOTAL ENVIRONMENT

A review of the pathways of human exposure to poly- and perfluoroalkyl substances (PFASs) and present understanding of health effects

(2018) Elsie M. Sunderland et al.   Journal of Exposure Science and Environmental Epidemiology

Exploring the Effect of Rotenone—A Known Inducer of Parkinson’s Disease—On Mitochondrial Dynamics in Dictyostelium discoideum

(2018) Ethan Chernivec et al.   Cells

The PFOA substitute GenX detected in the environment near a fluoropolymer manufacturing plant in the Netherlands

(2018) S.H. Brandsma et al.   CHEMOSPHERE

Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans

(2017) Shachi Shuchi Smita et al.   FREE RADICAL RESEARCH

Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms

(2017) Aurélie de Rus Jacquet et al.   JOURNAL OF ETHNOPHARMACOLOGY

Detailed NMR investigation of cyclodextrin-perfluorinated surfactant interactions in aqueous media

(2017) Mary Jo Weiss-Errico et al.   JOURNAL OF HAZARDOUS MATERIALS

From the Cover: Harmane-Induced Selective Dopaminergic Neurotoxicity in Caenorhabditis elegans

(2017) Shreesh Raj Sammi et al.   TOXICOLOGICAL SCIENCES

Uptake and Depuration of Four Per/Polyfluoroalkyl Substances (PFASS) in Northern Leopard Frog Rana pipiens Tadpoles

(2017) Gary M. Hoover et al.   Environmental Science & Technology Letters

Chronic Exposure to Perfluorooctane Sulfonate Reduces Lifespan of Caenorhabditis elegans Through Insulin/IGF-1 Signaling

(2016) Tiantian Xu et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes

(2016) Aris Polyzos et al.   HUMAN MOLECULAR GENETICS

TheC. elegansmodel in toxicity testing

(2016) Piper Reid Hunt   JOURNAL OF APPLIED TOXICOLOGY

1-Methyl-4-propan-2-ylbenzene from Thymus vulgaris Attenuates Cholinergic Dysfunction

(2016) Shreesh Raj Sammi et al.   MOLECULAR NEUROBIOLOGY

The Mitochondria-Regulated Immune Pathway Activated in the C. elegans Intestine Is Neuroprotective

(2016) Madhusudana Rao Chikka et al.   Cell Reports

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

(2016) Tanja Krainz et al.   ACS Central Science

Role of Mitochondria in Neurodegenerative Diseases: Mitochondria as a Therapeutic Target in Alzheimer's Disease

(2016) P. Hemachandra Reddy   CNS SPECTRUMS

Lifespan extension and increased resistance to environmental stressors by N-Acetyl-L-Cysteine in Caenorhabditis elegans

(2015) SI Oh et al.   Clinics

Brain region-specific perfluoroalkylated sulfonate (PFSA) and carboxylic acid (PFCA) accumulation and neurochemical biomarker Responses in east Greenland polar Bears (Ursus maritimus)

(2015) Kathrine Eggers Pedersen et al.   ENVIRONMENTAL RESEARCH

A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances and PINK1-dependent autophagy in C. elegans

(2015) B A Martinez et al.   Cell Death & Disease

PFOS Disturbs BDNF-ERK-CREB Signalling in Association with Increased MicroRNA-22 in SH-SY5Y Cells

(2015) Wu Li et al.   Biomed Research International

Dopamine Modulation of Avoidance Behavior in Caenorhabditis elegans Requires the NMDA Receptor NMR-1

(2014) Melvin Baidya et al.   PLoS One

Chronic Exposure to Perfluorooctane Sulfonate Induces Behavior Defects and Neurotoxicity through Oxidative Damages, In Vivo and In Vitro

(2014) Na Chen et al.   PLoS One

Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

(2014) Claudia P. González-Hunt et al.   PLoS One

Mitochondrial dysfunction, oxidative stress and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson’s model

(2014) A Ray et al.   Cell Death & Disease

Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases

(2014) Adanna G. Alexander et al.   Frontiers in Genetics

The effect of small molecules on nuclear-encoded translation diseases

(2013) Devorah Soiferman et al.   BIOCHIMIE

The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans

(2013) Julia Bornhorst et al.   Metallomics

A single neonatal exposure to perfluorohexane sulfonate (PFHxS) affects the levels of important neuroproteins in the developing mouse brain

(2013) Iwa Lee et al.   NEUROTOXICOLOGY

RNAi of cat-2, a Putative Tyrosine Hydroxylase, Increases Alpha Synuclein Aggregation and Associated Effects in Transgenic C. elegans

(2012) Supinder Kaur et al.   CNS & Neurological Disorders-Drug Targets

Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: A critical review of recent literature

(2012) Gloria B. Post et al.   ENVIRONMENTAL RESEARCH

Pharmacological assays reveal age-related changes in synaptic transmission at the Caenorhabditis elegans neuromuscular junction that are modified by reduced insulin signalling

(2012) B. Mulcahy et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

(2012) Jing Ji et al.   NATURE NEUROSCIENCE

Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease

(2012) Zhiyin Xun et al.   Cell Reports

Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

(2011) Balaraman Kalyanaraman et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)

(2010) Kyle Steenland et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bioconcentration of perfluorinated compounds in blackrock fish, Sebastes schlegeli, at different salinity levels

(2010) Junho Jeon et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Protective effect of N-acetylcysteine supplementation on mitochondrial oxidative stress and mitochondrial enzymes in cerebral cortex of streptozotocin-treated diabetic rats

(2010) Sukhdev S. Kamboj et al.   MITOCHONDRION

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

(2010) Chen Yao et al.   NEUROBIOLOGY OF DISEASE

Prenatal Exposure to PFOS or PFOA Alters Motor Function in Mice in a Sex-Related Manner

(2010) Natalia Onishchenko et al.   NEUROTOXICITY RESEARCH

Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans

(2010) Alexandre Benedetto et al.   PLoS Genetics

Effects of perfluorooctanoate and perfluorooctane sulfonate exposure on hepatoma Hep G2 cells

(2009) Xiao-Zhong Hu et al.   ARCHIVES OF TOXICOLOGY

Glutathione—a review on its role and significance in Parkinson’s disease

(2009) Heather L. Martin et al.   FASEB JOURNAL

Four Decades of Neurodegenerative Disease Research: How Far We Have Come!

(2009) A. B. Young   JOURNAL OF NEUROSCIENCE

Comparison of the toxicokinetic behavior of perfluorohexanoic acid (PFHxA) and nonafluorobutane-1-sulfonic acid (PFBS) in cynomolgus monkeys and rats

(2009) Christopher P. Chengelis et al.   REPRODUCTIVE TOXICOLOGY

Neonatal Exposure to PFOS and PFOA in Mice Results in Changes in Proteins which are Important for Neuronal Growth and Synaptogenesis in the Developing Brain

(2009) Niclas Johansson et al.   TOXICOLOGICAL SCIENCES

Dopamine neuron degeneration induced by MPP+ is independent of CED-4 pathway in Caenorhabditis elegans

(2008) Pu Pu et al.   CELL RESEARCH

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS