Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Autophagy protects against hypoxic injury inC. elegans

(2014) Victor Samokhvalov et al.   Autophagy

Mitochondrial DNA damage: Molecular marker of vulnerable nigral neurons in Parkinson's disease

(2014) Laurie H. Sanders et al.   NEUROBIOLOGY OF DISEASE

Mitochondria as a Target of Environmental Toxicants

(2013) Joel N. Meyer et al.   TOXICOLOGICAL SCIENCES

Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans

(2013) Maxwell CK Leung et al.   BMC Pharmacology & Toxicology

Neural Regeneration in Caenorhabditis elegans

(2012) Rachid El Bejjani et al.   Annual Review of Genetics

Regional susceptibilities to mitochondrial dysfunctions in the CNS

(2012) Milena Pinto et al.   BIOLOGICAL CHEMISTRY

In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans

(2012) Senyene E. Hunter et al.   DNA REPAIR

Minimizing the damage: repair pathways keep mitochondrial DNA intact

(2012) Lawrence Kazak et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rotenone, Paraquat, and Parkinson’s Disease

(2011) Caroline M. Tanner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Is Pesticide Use Related to Parkinson Disease? Some Clues to Heterogeneity in Study Results

(2011) Marianne van der Mark et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Striatal Dysfunctions Associated with Mitochondrial DNA Damage in Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

(2011) A. M. Pickrell et al.   JOURNAL OF NEUROSCIENCE

6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death

(2011) Alison I Bernstein et al.   Molecular Neurodegeneration

Exposure to Mn/Zn ethylene-bis-dithiocarbamate and glyphosate pesticides leads to neurodegeneration in Caenorhabditis elegans

(2011) Rekek Negga et al.   NEUROTOXICOLOGY

The Role of Environmental Exposures in Neurodegeneration and Neurodegenerative Diseases

(2011) Jason R. Cannon et al.   TOXICOLOGICAL SCIENCES

Top-down control analysis of the cadmium effects on molluscan mitochondria and the mechanisms of cadmium-induced mitochondrial dysfunction

(2010) Ilya O. Kurochkin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

DNA Adducts of Decarbamoyl Mitomycin C Efficiently Kill Cells without Wild-Type p53 Resulting from Proteasome-Mediated Degradation of Checkpoint Protein 1

(2010) Ernest K. Boamah et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease

(2010) Rodrigo Franco et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Pharmacologic effects on mitochondrial function

(2010) Bruce H. Cohen   Developmental Disabilities Research Reviews

QPCR: a tool for analysis of mitochondrial and nuclear DNA damage in ecotoxicology

(2010) Joel N. Meyer   ECOTOXICOLOGY

Mito-Conundrum: Unraveling Environmental Effects on Mitochondria

(2010) Charles W. Schmidt   ENVIRONMENTAL HEALTH PERSPECTIVES

Manganese and Parkinson’s Disease: A Critical Review and New Findings

(2010) Tomás R. Guilarte   ENVIRONMENTAL HEALTH PERSPECTIVES

The QPCR assay for analysis of mitochondrial DNA damage, repair, and relative copy number

(2010) Senyene E. Hunter et al.   METHODS

Meeting report: Identification of biomarkers for early detection of mitochondrial dysfunction

(2010) Daniel T. Shaughnessy et al.   MITOCHONDRION

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M 1 dG

(2010) Susan D. Cline et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans Generates Biologically Relevant Levels of Genotoxic Metabolites from Aflatoxin B1 but Not Benzo[a]pyrene In Vivo

(2010) Maxwell C. K. Leung et al.   TOXICOLOGICAL SCIENCES

Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans

(2010) Alexandre Benedetto et al.   PLoS Genetics

The DLK-1 Kinase Promotes mRNA Stability and Local Translation in C. elegans Synapses and Axon Regeneration

(2009) Dong Yan et al.   CELL

Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease

(2009) Alexandre Benedetto et al.   CHEMICAL REVIEWS

LRRK2 Modulates Vulnerability to Mitochondrial Dysfunction in Caenorhabditis elegans

(2009) S. Saha et al.   JOURNAL OF NEUROSCIENCE

Hepatic Mitochondrial DNA Depletion after an Alcohol Binge in Mice: Probable Role of Peroxynitrite and Modulation by Manganese Superoxide Dismutase

(2009) I. Larosche et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cadmium and mitochondria

(2009) Giuseppe Cannino et al.   MITOCHONDRION

VPS41, a protein involved in lysosomal trafficking, is protective in Caenorhabditis elegans and mammalian cellular models of Parkinson's disease

(2009) Qingmin Ruan et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development

(2009) Ivana Bratic et al.   NUCLEIC ACIDS RESEARCH

Application of a Mathematical Model to Describe the Effects of Chlorpyrifos on Caenorhabditis elegans Development

(2009) Windy A. Boyd et al.   PLoS One

Axon Regeneration Requires a Conserved MAP Kinase Pathway

(2009) M. Hammarlund et al.   SCIENCE

Mechanisms of cadmium carcinogenesis☆

(2009) Pius Joseph   TOXICOLOGY AND APPLIED PHARMACOLOGY

Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

(2009) Francesca Cicchetti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mitochondrial Disorders in the Nervous System

(2008) Salvatore DiMauro et al.   Annual Review of Neuroscience

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

(2008) Marwan Maalouf et al.   BRAIN RESEARCH REVIEWS

Meeting Report: Consensus Statement—Parkinson’s Disease and the Environment: Collaborative on Health and the Environment and Parkinson’s Action Network (CHE PAN) Conference 26–28 June 2007

(2008) Jeff Bronstein et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells

(2008) Hatasu Kobayashi et al.   FREE RADICAL RESEARCH

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

Mitochondrial DNA repair in aging and disease

(2008) Nadiya M. Druzhyna et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Do early-life insults contribute to the late-life development of Parkinson and Alzheimer diseases?

(2008) Diane B. Miller et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans

(2008) Alexander R. Mendenhall et al.   PHYSIOLOGICAL GENOMICS

The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?

(2008) Hirokazu Fukui et al.   TRENDS IN NEUROSCIENCES