Extracellular Dopamine Potentiates Mn-Induced Oxidative Stress, Lifespan Reduction, and Dopaminergic Neurodegeneration in a BLI-3–Dependent Manner in Caenorhabditis elegans

Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1

(2009) Sang-Kyu Park et al.   AGING CELL

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets

(2009) Kathleen E. Dennis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Functional assessment of Nramp-like metal transporters and manganese in Caenorhabditis elegans

(2009) Jaya Bandyopadhyay et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Manganese-Induced Dopaminergic Neurodegeneration: Insights into Mechanisms and Genetics Shared with Parkinson’s Disease

(2009) Alexandre Benedetto et al.   CHEMICAL REVIEWS

A Pathogenesis Assay UsingSaccharomycescerevisiaeandCaenorhabditiselegansReveals Novel Roles for Yeast AP-1, Yap1, and Host Dual Oxidase BLI-3 in Fungal Pathogenesis

(2009) Charu Jain et al.   EUKARYOTIC CELL

The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease

(2009) Antonio Cuadrado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer’s disease

(2009) Magali Dumont et al.   FASEB JOURNAL

Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans

(2009) V. Chavez et al.   INFECTION AND IMMUNITY

Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth

(2009) Julia Sämann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined Extracellular Matrix Cross-linking Activity of the Peroxidase MLT-7 and the Dual Oxidase BLI-3 Is Critical for Post-embryonic Viability inCaenorhabditis elegans

(2009) Melanie C. Thein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Dopamine transporter glycosylation correlates with the vulnerability of midbrain dopaminergic cells in Parkinson's disease

(2009) Domingo Afonso-Oramas et al.   NEUROBIOLOGY OF DISEASE

SMF-1, SMF-2 and SMF-3 DMT1 Orthologues Regulate and Are Regulated Differentially by Manganese Levels in C. elegans

(2009) Catherine Au et al.   PLoS One

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

(2009) Pei-Chun Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preweaning manganese exposure causes hyperactivity, disinhibition, and spatial learning and memory deficits associated with altered dopamine receptor and transporter levels

(2009) Cynthia H. Kern et al.   SYNAPSE

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

(2009) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Viral parkinsonism

(2008) Haeman Jang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Molecular mechanism of manganese exposure-induced dopaminergic toxicity

(2008) K. Prabhakaran et al.   BRAIN RESEARCH BULLETIN

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

HelicobacterHypothesis for Idiopathic Parkinsonism: Before and Beyond

(2008) R. John Dobbs et al.   HELICOBACTER

A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans

(2008) Tomoki Kuwahara et al.   HUMAN MOLECULAR GENETICS

Postnatal manganese exposure alters dopamine transporter function in adult rats: Potential impact on nonassociative and associative processes

(2008) S.A. McDougall et al.   NEUROSCIENCE

Acetaminophen attenuates dopamine neuron degeneration in animal models of Parkinson's disease

(2008) Cody J. Locke et al.   NEUROSCIENCE LETTERS

Manganese transport in eukaryotes: The role of DMT1

(2008) Catherine Au et al.   NEUROTOXICOLOGY

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

(2008) S. Hamamichi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging

(2008) Tjakko J. van Ham et al.   PLoS Genetics

Proteomics ofCaenorhabditis elegans over-expressing humanα-synuclein analyzed by fluorogenic derivatization–liquid chromatography/tandem mass spectrometry: identification of actin and several ribosomal proteins as negative markers at early Parkinson's disease stages

(2007) Tomoko Ichibangase et al.   BIOMEDICAL CHROMATOGRAPHY