MUC1-C activates the TAK1 inflammatory pathway in colon cancer

Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling

(2015) Patty C.H. Cai et al.   Oncotarget

TAK1 control of cell death

(2014) S R Mihaly et al.   CELL DEATH AND DIFFERENTIATION

MUC1-C Oncoprotein Activates ERK→C/EBPβ Signaling and Induction of Aldehyde Dehydrogenase 1A1 in Breast Cancer Cells

(2013) Maroof Alam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial–mesenchymal transition

(2013) H Rajabi et al.   ONCOGENE

Cell type-specific function of TAK1 in innate immune signaling

(2013) Adebusola A. Ajibade et al.   TRENDS IN IMMUNOLOGY

Inhibition of transforming growth factor-β-activated kinase-1 blocks cancer cell adhesion, invasion and metastasis

(2012) D M Ray et al.   BRITISH JOURNAL OF CANCER

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

(2012) Ryan B. Corcoran et al.   CANCER CELL

TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers

(2012) Anurag Singh et al.   CELL

MUC1-C Oncoprotein Induces TCF7L2 Transcription Factor Activation and Promotes Cyclin D1 Expression in Human Breast Cancer Cells

(2012) Hasan Rajabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

(2012) D W Kufe   ONCOGENE

Epithelial transforming growth factor  -activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

(2012) E. Omori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

Intestinal Inflammation and Cancer

(2011) Thomas A. Ullman et al.   GASTROENTEROLOGY

A Monoclonal Antibody Against the Oncogenic Mucin 1 Cytoplasmic Domain

(2011) Govind Panchamoorthy et al.   HYBRIDOMA

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

(2011) Daniel T. Starczynowski et al.   JOURNAL OF CLINICAL INVESTIGATION

Dependence on the MUC1-C Oncoprotein in Non-Small Cell Lung Cancer Cells

(2011) D. Raina et al.   MOLECULAR CANCER THERAPEUTICS

MUC1-C Oncoprotein Promotes STAT3 Activation in an Autoinductive Regulatory Loop

(2011) R. Ahmad et al.   Science Signaling

Importance and regulation of the colonic mucus barrier in a mouse model of colitis

(2010) J. Petersson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ablation of TAK1 Upregulates Reactive Oxygen Species and Selectively Kills Tumor Cells

(2010) E. Omori et al.   CANCER RESEARCH

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor

(2009) R. Ahmad et al.   CANCER RESEARCH

MUC1-Induced Transcriptional Programs Associated with Tumorigenesis Predict Outcome in Breast and Lung Cancer

(2009) N. N. Khodarev et al.   CANCER RESEARCH

Two Mechanistically and Temporally Distinct NF- B Activation Pathways in IL-1 Signaling

(2009) K. Yamazaki et al.   Science Signaling

Aberrant Expression of MUC1 Mucin in Pediatric Inflammatory Bowel Disease

(2008) Anna E. Furr et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

MUC1 and colorectal cancer pathophysiology considerations

(2008) Yaron Niv   WORLD JOURNAL OF GASTROENTEROLOGY