Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization

Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease

(2015) Ana Serrano-Puebla et al.   Annals of the New York Academy of Sciences

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death

(2015) Jane L. Armstrong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Biophysical properties of sphingosine, ceramides and other simple sphingolipids

(2014) Félix M. Goñi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

(2014) Douglas R. Green et al.   CELL

Autosis and autophagic cell death: the dark side of autophagy

(2014) Y Liu et al.   CELL DEATH AND DIFFERENTIATION

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The pleiotropic roles of sphingolipid signaling in autophagy

(2014) Y Li et al.   Cell Death & Disease

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

(2013) María Salazar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Autophagy paradox and ceramide

(2013) Wenhui Jiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Transformation-Associated Changes in Sphingolipid Metabolism Sensitize Cells to Lysosomal Cell Death Induced by Inhibitors of Acid Sphingomyelinase

(2013) Nikolaj H.T. Petersen et al.   CANCER CELL

Lysosomal cell death at a glance

(2013) S. Aits et al.   JOURNAL OF CELL SCIENCE

Emerging regulation and functions of autophagy

(2013) Patricia Boya et al.   NATURE CELL BIOLOGY

ATG7 deficiency suppresses apoptosis and cell death induced by lysosomal photodamage

(2012) David H. Kessel et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Dihydroceramide delays cell cycle G1/S transition via activation of ER stress and induction of autophagy

(2012) Vincenzo Gagliostro et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Integration of non-vesicular and vesicular transport processes at the Golgi complex by the PKD–CERT network

(2011) Monilola A. Olayioye et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide

(2011) Qing Jiang et al.   INTERNATIONAL JOURNAL OF CANCER

Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains

(2010) Catarina R. Vieira et al.   CHEMISTRY & BIOLOGY

Plasma membrane contributes to the formation of pre-autophagosomal structures

(2010) Brinda Ravikumar et al.   NATURE CELL BIOLOGY

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells

(2009) Paola Signorelli et al.   CANCER LETTERS

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of ceramide and other simple sphingolipids on membrane lateral structure

(2008) Félix M. Goñi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

Casein Kinase Iγ2 Down-Regulates Trafficking of Ceramide in the Synthesis of Sphingomyelin

(2008) Nario Tomishige et al.   MOLECULAR BIOLOGY OF THE CELL

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosomal membrane permeabilization in cell death

(2008) P Boya et al.   ONCOGENE