Gamma-tocotrienol induces apoptosis and autophagy in prostate cancer cells by increasing intracellular dihydrosphingosine and dihydroceramide

Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling

(2010) Sook Kyung Park et al.   BREAST CANCER RESEARCH AND TREATMENT

 -Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment

(2010) A. B. Kunnumakkara et al.   CANCER RESEARCH

A  -tocopherol-rich mixture of tocopherols inhibits chemically induced lung tumorigenesis in A/J mice and xenograft tumor growth

(2010) G. Lu et al.   CARCINOGENESIS

Natural Forms of Vitamin E and 13'-Carboxychromanol, a Long-Chain Vitamin E Metabolite, Inhibit Leukotriene Generation from Stimulated Neutrophils by Blocking Calcium Influx and Suppressing 5-Lipoxygenase Activity, Respectively

(2010) Z. Jiang et al.   JOURNAL OF IMMUNOLOGY

Mixed Tocotrienols Inhibit Prostate Carcinogenesis in TRAMP Mice

(2010) Avantika Barve et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Endoplasmic reticulum stress mediates γ-tocotrienol-induced apoptosis in mammary tumor cells

(2009) Vikram B. Wali et al.   APOPTOSIS

Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

(2009) Jesse Coward et al.   Autophagy

Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells

(2009) Paola Signorelli et al.   CANCER LETTERS

A  -Tocopherol-Rich Mixture of Tocopherols Inhibits Colon Inflammation and Carcinogenesis in Azoxymethane and Dextran Sulfate Sodium-Treated Mice

(2009) J. Ju et al.   Cancer Prevention Research

Cancer-preventive activities of tocopherols and tocotrienols

(2009) Jihyeung Ju et al.   CARCINOGENESIS

Mixed Tocopherols Prevent Mammary Tumorigenesis by Inhibiting Estrogen Action and Activating PPAR- 

(2009) H. J. Lee et al.   CLINICAL CANCER RESEARCH

Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways

(2009) Can E. Senkal et al.   FASEB JOURNAL

γ-Tocotrienol and γ-Tocopherol Are Primarily Metabolized to Conjugated 2-(β-carboxyethyl)-6-Hydroxy-2,7,8-Trimethylchroman and Sulfated Long-Chain Carboxychromanols in Rats

(2009) Helene Freiser et al.   JOURNAL OF NUTRITION

Overexpression of degenerative spermatocyte homolog 1 up-regulates the expression of cyclin D1 and enhances metastatic efficiency in esophageal carcinoma Eca109 cells

(2009) Wu Zhou et al.   MOLECULAR CARCINOGENESIS

γ-Tocotrienol suppresses prostate cancer cell proliferation and invasion through multiple-signalling pathways

(2008) W N Yap et al.   BRITISH JOURNAL OF CANCER

γ-Tocopherol-enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice

(2008) Avantika Barve et al.   INTERNATIONAL JOURNAL OF CANCER

The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis

(2008) Susanne Schiffmann et al.   JOURNAL OF LIPID RESEARCH

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases

(2008) Q. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA