Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs

Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells

(2018) Alexis Autour et al.   Nature Communications

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells

(2018) Esther Braselmann et al.   Nature Chemical Biology

Fluoromodules Consisting of a Promiscuous RNA Aptamer and Red or Blue Fluorogenic Cyanine Dyes: Selection, Characterization, and Bioimaging

(2017) Xiaohong Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically Encoded Fluorescent RNA Sensor for Ratiometric Imaging of MicroRNA in Living Tumor Cells

(2017) Zhan-Ming Ying et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A homodimer interface without base pairs in an RNA mimic of red fluorescent protein

(2017) Katherine Deigan Warner et al.   Nature Chemical Biology

Imaging RNA polymerase III transcription using a photostable RNA–fluorophore complex

(2017) Wenjiao Song et al.   Nature Chemical Biology

Structural basis for high-affinity fluorophore binding and activation by RNA Mango

(2017) Robert J Trachman et al.   Nature Chemical Biology

An improved MS2 system for accurate reporting of the mRNA life cycle

(2017) Evelina Tutucci et al.   NATURE METHODS

Real-Time Imaging of Translation on Single mRNA Transcripts in Live Cells

(2016) Chong Wang et al.   CELL

Dynamics of Translation of Single mRNA Molecules In Vivo

(2016) Xiaowei Yan et al.   CELL

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

(2016) David A. Nelles et al.   CELL

Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system

(2016) Shipeng Shao et al.   NUCLEIC ACIDS RESEARCH

Translation dynamics of single mRNAs in live cells and neurons

(2016) B. Wu et al.   SCIENCE

Real-time quantification of single RNA translation dynamics in living cells

(2016) T. Morisaki et al.   SCIENCE

RNA Fluorescence with Light-Up Aptamers

(2016) Jonathan Ouellet   Frontiers in Chemistry

Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes

(2016) Cibran Perez-Gonzalez et al.   Frontiers in Chemistry

A Covalent Approach for Site-Specific RNA Labeling in Mammalian Cells

(2015) Fahui Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Mechanism of RNA Mimics of Green Fluorescent Protein

(2015) Mingxu You et al.   Annual Review of Biophysics

Control of Transcript Variability in Single Mammalian Cells

(2015) Nico Battich et al.   CELL

Site-Specific Covalent Labeling of RNA by Enzymatic Transglycosylation

(2015) Seth C. Alexander et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

SART3-Dependent Accumulation of Incomplete Spliceosomal snRNPs in Cajal Bodies

(2015) Ivan Novotný et al.   Cell Reports

RNA Mango Aptamer-Fluorophore: A Bright, High-Affinity Complex for RNA Labeling and Tracking

(2014) Elena V. Dolgosheina et al.   ACS Chemical Biology

Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution

(2014) Grigory S. Filonov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plug-and-Play Fluorophores Extend the Spectral Properties of Spinach

(2014) Wenjiao Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A G-quadruplex–containing RNA activates fluorescence in a GFP-like fluorophore

(2014) Hao Huang et al.   Nature Chemical Biology

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

(2014) Katherine Deigan Warner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Contact-Mediated Quenching for RNA Imaging in Bacteria with a Fluorophore-Binding Aptamer

(2013) Murat Sunbul et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

(2013) Baohui Chen et al.   CELL

Engineered proteins with Pumilio/fem-3mRNA binding factor scaffold to manipulate RNA metabolism

(2013) Yang Wang et al.   FEBS Journal

Understanding the Photophysics of the Spinach–DFHBI RNA Aptamer–Fluorogen Complex To Improve Live-Cell RNA Imaging

(2013) Kyu Young Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumour heterogeneity and cancer cell plasticity

(2013) Corbin E. Meacham et al.   NATURE

Image-based transcriptomics in thousands of single human cells at single-molecule resolution

(2013) Nico Battich et al.   NATURE METHODS

Imaging bacterial protein expression using genetically encoded RNA sensors

(2013) Wenjiao Song et al.   NATURE METHODS

A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat–containing RNA

(2013) Rita L Strack et al.   NATURE METHODS

Photochemical properties of Spinach and its use in selective imaging

(2013) Pengcheng Wang et al.   Chemical Science

Spatiotemporal control of gene expression by a light-switchable transgene system

(2012) Xue Wang et al.   NATURE METHODS

Fluorescence Imaging of Cellular Metabolites with RNA

(2012) Jeremy S. Paige et al.   SCIENCE

An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility

(2012) Hye Yoon Park et al.   Cell Reports

Primary Role for Endoplasmic Reticulum-bound Ribosomes in Cellular Translation Identified by Ribosome Profiling

(2011) David W. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

RNA Mimics of Green Fluorescent Protein

(2011) J. S. Paige et al.   SCIENCE

Recent advances in instrumentation for absolute emission quantum yield measurements

(2010) Hitoshi Ishida et al.   COORDINATION CHEMISTRY REVIEWS

Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression

(2010) Kannanganattu V. Prasanth et al.   MOLECULAR BIOLOGY OF THE CELL

Functional roles for noise in genetic circuits

(2010) Avigdor Eldar et al.   NATURE

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Imaging intracellular RNA distribution and dynamics in living cells

(2009) Sanjay Tyagi   NATURE METHODS

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Transcription monitoring using fused RNA with a dye-binding light-up aptamer as a tag: a blue fluorescent RNA

(2008) Shinsuke Sando et al.   CHEMICAL COMMUNICATIONS

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS

Synthesis of New Fluorogenic Cyanine Dyes and Incorporation into RNA Fluoromodules

(2008) Tudor P. Constantin et al.   ORGANIC LETTERS