Engineered proteins with Pumilio/fem-3mRNA binding factor scaffold to manipulate RNA metabolism

Engineering RNA-binding proteins for biology

(2013) Yu Chen et al.   FEBS Journal

Fluorescent Probes for Imaging Endogenous β-Actin mRNA in Living Cells Using Fluorescent Protein-Tagged Pumilio

(2012) Hideaki Yoshimura et al.   ACS Chemical Biology

Gene transfer to skeletal muscle by site-specific delivery of electroporation and ultrasound

(2012) Yuanli Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Triplet repeats in transcripts: structural insights into RNA toxicity

(2012) Paulina Galka-Marciniak et al.   BIOLOGICAL CHEMISTRY

Pumilio facilitates miRNA regulation of the E2F3 oncogene

(2012) W. O. Miles et al.   GENES & DEVELOPMENT

Human Pumilio Proteins Recruit Multiple Deadenylases to Efficiently Repress Messenger RNAs

(2012) Jamie Van Etten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-based nanocarriers as promising drug and gene delivery systems

(2012) Ahmed O. Elzoghby et al.   JOURNAL OF CONTROLLED RELEASE

A Eukaryotic Translation Initiation Factor 4E-Binding Protein Promotes mRNA Decapping and Is Required for PUF Repression

(2012) N. H. Blewett et al.   MOLECULAR AND CELLULAR BIOLOGY

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

(2012) Karen Adelman et al.   NATURE REVIEWS GENETICS

A complex network of factors with overlapping affinities represses splicing through intronic elements

(2012) Yang Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules

(2012) Yang Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II

(2012) Stéphane Larochelle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Patterns and plasticity in RNA-protein interactions enable recruitment of multiple proteins through a single site

(2012) C. T. Valley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-penetrating peptides: breaking through to the other side

(2012) Erez Koren et al.   TRENDS IN MOLECULAR MEDICINE

Pre-mRNA splicing in disease and therapeutics

(2012) Ravi K. Singh et al.   TRENDS IN MOLECULAR MEDICINE

Engineering RNA endonucleases with customized sequence specificities

(2012) Rajarshi Choudhury et al.   Nature Communications

An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility

(2012) Hye Yoon Park et al.   Cell Reports

Cooperativity in RNA-Protein Interactions: Global Analysis of RNA Binding Specificity

(2012) Zachary T. Campbell et al.   Cell Reports

A Combinatorial Amino Acid Code for RNA Recognition by Pentatricopeptide Repeat Proteins

(2012) Alice Barkan et al.   PLoS Genetics

Visualization of Nonengineered Single mRNAs in Living Cells Using Genetically Encoded Fluorescent Probes

(2011) Toshimichi Yamada et al.   ANALYTICAL CHEMISTRY

Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains

(2011) Shuyun Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Divergence of Pumilio/fem-3mRNA Binding Factor (PUF) Protein Specificity through Variations in an RNA-binding Pocket

(2011) Chen Qiu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drosophila Pumilio Protein Contains Multiple Autonomous Repression Domains That Regulate mRNAs Independently of Nanos and Brain Tumor

(2011) C. A. Weidmann et al.   MOLECULAR AND CELLULAR BIOLOGY

A universal code for RNA recognition by PUF proteins

(2011) Aleksandra Filipovska et al.   Nature Chemical Biology

A transgenic mouse for in vivo detection of endogenous labeled mRNA

(2011) Timothée Lionnet et al.   NATURE METHODS

The prospects for designer single-stranded RNA-binding proteins

(2011) Joel P Mackay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeted translational regulation using the PUF protein family scaffold

(2011) A. Cooke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stacking interactions in PUF-RNA complexes

(2011) Y. Y. Koh et al.   RNA

Divergent RNA binding specificity of yeast Puf2p

(2011) Y. Yosefzon et al.   RNA

Alternate Modes of Cognate RNA Recognition by Human PUMILIO Proteins

(2011) Gang Lu et al.   STRUCTURE

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Developmental RNA processing of 3'UTRs in Hox mRNAs as a context-dependent mechanism modulating visibility to microRNAs

(2010) S. Thomsen et al.   DEVELOPMENT

Toward a General Approach for RNA-Templated Hierarchical Assembly of Split-Proteins

(2010) Jennifer L. Furman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Pumilio-induced RNA structure switch in p27-3′ UTR controls miR-221 and miR-222 accessibility

(2010) Martijn Kedde et al.   NATURE CELL BIOLOGY

Genome-wide analysis of mRNA targets for Caenorhabditis elegans FBF, a conserved stem cell regulator

(2010) Aaron M. Kershner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative polyadenylation of MeCP2: influence of cis-acting elements and trans-acting factors

(2010) Catherine M. Newnham et al.   RNA Biology

Turnover of AU-rich-containing mRNAs during stress: a matter of survival

(2010) Christopher von Roretz et al.   Wiley Interdisciplinary Reviews-RNA

Roles of Puf proteins in mRNA degradation and translation

(2010) Melanie A. Miller et al.   Wiley Interdisciplinary Reviews-RNA

Engineering splicing factors with designed specificities

(2009) Yang Wang et al.   NATURE METHODS

Reprogramming of 3′ Untranslated Regions of mRNAs by Alternative Polyadenylation in Generation of Pluripotent Stem Cells from Different Cell Types

(2009) Zhe Ji et al.   PLoS One

A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs

(2009) D. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for specific recognition of multiple mRNA targets by a PUF regulatory protein

(2009) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single C. elegans PUF protein binds RNA in multiple modes

(2009) Y. Y. Koh et al.   RNA

RNA-splicing endonuclease structure and function

(2008) K. Calvin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p

(2008) Matthew T Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Live-cell imaging of viral RNA genomes using a Pumilio-based reporter

(2008) Jens Tilsner et al.   PLANT JOURNAL

A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity

(2008) C. R. Stumpf et al.   RNA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

Structures of Human Pumilio with Noncognate RNAs Reveal Molecular Mechanisms for Binding Promiscuity

(2008) Yogesh K. Gupta et al.   STRUCTURE