Unraveling the Molecular Mechanism of Traditional Chinese Medicine: Formulas Against Acute Airway Viral Infections as Examples

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes

(2019) Chang Tu et al.   Frontiers in Pharmacology

Network Pharmacology-Based Investigation of Protective Mechanism of Aster tataricus on Lipopolysaccharide-Induced Acute Lung Injury

(2019) Yijun Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antiviral effects of Ma Huang Tang against H1N1 influenza virus infection in vitro and in an ICR pneumonia mouse model

(2018) Wenyang Wei et al.   BIOMEDICINE & PHARMACOTHERAPY

Antiasthmatic Effects of Sanglong Pingchuan Decoction through Inducing a Balanced Th1/Th2 Immune Response

(2018) Binnian Zhu et al.   Evidence-based Complementary and Alternative Medicine

Galgeun-tang Attenuates Cigarette Smoke and Lipopolysaccharide Induced Pulmonary Inflammation via IκBα/NF-κB Signaling

(2018) Na-Rae Shin et al.   MOLECULES

6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype

(2018) Jingjing Yao et al.   Food & Function

Panax ginseng and Panax quinquefolius : From pharmacology to toxicology

(2017) Cesare Mancuso et al.   FOOD AND CHEMICAL TOXICOLOGY

Diet and the Microbiome

(2017) Nida Murtaza et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Schisandrin B inhibits LPS-induced inflammatory response in human umbilical vein endothelial cells by activating Nrf2

(2017) Qiuning Lin et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Studies on the competitive binding of cleviprex and flavonoids to plasma protein by multi-spectroscopic methods: A prediction of food-drug interaction

(2017) Xin Wang et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Pterodontic Acid Isolated from Laggera pterodonta Inhibits Viral Replication and Inflammation Induced by Influenza A Virus

(2017) Wenda Guan et al.   MOLECULES

The Pharmacological Actions of Ephedrine Alkaloids-free Ephreda Herb Extract and Preparation for Clinical Application

(2017) Sumiko Hyuga   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Post-treatment with Ma-Huang-Tang ameliorates cold-warm-cycles induced rat lung injury

(2017) Meng-Meng Xiao et al.   Scientific Reports

Antitussive, anti-pyretic and toxicological evaluation of Ma-Xing-Gan-Shi-Tang in rodents

(2016) Yu-Chin Lin et al.   BMC Complementary and Alternative Medicine

Could the gut microbiota reconcile the oral bioavailability conundrum of traditional herbs?

(2016) Feng Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antitussive activity of the Schisandra chinensis fruit polysaccharide (SCFP-1) in guinea pigs models

(2016) Shan Zhong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Traditional Chinese medicine therapy decreases the pneumonia risk in patients with dementia

(2016) Shun-Ku Lin et al.   MEDICINE

Role of Intestinal Microbiota in Baicalin-Induced Drug Interaction and Its Pharmacokinetics

(2016) Keumhan Noh et al.   MOLECULES

The increased binding affinity of curcumin with human serum albumin in the presence of rutin and baicalin: A potential for drug delivery system

(2016) Bing-Mi Liu et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice

(2016) Yasuharu Watanabe et al.   Scientific Reports

Anti-septic activity of α-cubebenoate isolated from Schisandra chinensis

(2015) Minsoo Kook et al.   BMB Reports

Spectroscopic investigation on the food components–drug interaction: The influence of flavonoids on the affinity of nifedipine to human serum albumin

(2015) Xin Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Puerarin attenuates airway inflammation by regulation of eotaxin-3

(2015) Jing Wang et al.   IMMUNOLOGY LETTERS

Pinellia ternata lectin exerts a pro-inflammatory effect on macrophages by inducing the release of pro-inflammatory cytokines, the activation of the nuclear factor-κB signaling pathway and the overproduction of reactive oxygen species

(2015) HONG-LI YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Herb–drug interactions between Scutellariae Radix and mefenamic acid: Simultaneous investigation of pharmacokinetics, anti-inflammatory effect and gastric damage in rats

(2015) Sophia Yui Kau Fong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Yakammaoto inhibits enterovirus 71 infection by reducing viral attachment, internalization, replication, and translation

(2015) Chia-Feng Yeh et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Differential Inhibition of T Lymphocyte Proliferation and Cytokine Synthesis by [6]-Gingerol, [8]-Gingerol, and [10]-Gingerol

(2015) Megan Bernard et al.   PHYTOTHERAPY RESEARCH

The Pharmacological Activities of Licorice

(2015) Rui Yang et al.   PLANTA MEDICA

Anti-inflammatory activity of cinnamon (C. zeylanicum and C. cassia) extracts – identification of E-cinnamaldehyde and o-methoxy cinnamaldehyde as the most potent bioactive compounds

(2015) Dhanushka Gunawardena et al.   Food & Function

Antiviral Activity and Possible Mechanism of Action of Constituents Identified in Paeonia lactiflora Root toward Human Rhinoviruses

(2015) Luong Thi My Ngan et al.   PLoS One

ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury

(2014) Naga P Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Prescription pattern of Chinese herbal products for adult-onset asthma in Taiwan: a population-based study

(2014) Hung-Ming Wang et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Antipyretic and anti-asthmatic activities of traditional Chinese herb-pairs, Ephedra and Gypsum

(2014) Fen Mei et al.   Chinese Journal of Integrative Medicine

Identification of a novel anti-inflammatory compound, α-cubebenoate from Schisandra chinensis

(2014) Saeromi Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Uralsaponins M–Y, Antiviral Triterpenoid Saponins from the Roots of Glycyrrhiza uralensis

(2014) Wei Song et al.   JOURNAL OF NATURAL PRODUCTS

Traditional Chinese medicine treatments for upper respiratory tract infections/common colds in Taiwan

(2014) Jung-Sheng Yu et al.   European Journal of Integrative Medicine

Role of metabolism by intestinal microbiota in pharmacokinetics of oral baicalin

(2013) Mi Jeong Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Application of metabolomics on diagnosis and treatment of patients with psoriasis in traditional Chinese medicine

(2013) Chuanjian Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats

(2013) Xin Tian et al.   Evidence-based Complementary and Alternative Medicine

Xiao-Qing-Long-Tang (Sho-seiryu-to) inhibited cytopathic effect of human respiratory syncytial virus in cell lines of human respiratory tract

(2013) Jung San Chang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Interaction of baicalin with berberine for glucose uptake in 3T3-L1 adipocytes and HepG2 hepatocytes

(2013) Chang-Hua Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Yakammaoto inhibited human coxsackievirus B4 (CVB4)-induced airway and renal tubular injuries by preventing viral attachment, internalization, and replication

(2013) Ming Hong Yen et al.   JOURNAL OF ETHNOPHARMACOLOGY

A comparative study on anticoagulant activities of three Chinese herbal medicines from the genusPanaxand anticoagulant activities of ginsenosides Rg1 and Rg2

(2013) C. T. Li et al.   PHARMACEUTICAL BIOLOGY

Plasma metabolic profiling of normal and dysmenorrhea syndrome rats and the effects of Xiang–Fu–Si–Wu Decoction intervention

(2013) Pei Liu et al.   PHARMACEUTICAL BIOLOGY

Upper Respiratory Infections

(2013) Samuel N. Grief   PRIMARY CARE

Antiviral Effect of Cimicifugin from Cimicifuga foetida Against Human Respiratory Syncytial Virus

(2012) Kuo-Chih Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Xiao-Qing-Long-Tang attenuates allergic airway inflammation and remodeling in repetitive Dermatogoides pteronyssinus challenged chronic asthmatic mice model

(2012) Shulhn-Der Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza

(2012) Shigeki Nabeshima et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine

(2012) Pei Liu et al.   Molecular BioSystems

Mechanism of action of the suppression of influenza virus replication by Ko-Ken Tang through inhibition of the phosphatidylinositol 3-kinase/Akt signaling pathway and viral RNP nuclear export

(2011) Ming-Sian Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ge-Gen-Tang has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines

(2011) Jung San Chang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: As pillars of the bridge between Chinese and Western medicine

(2011) Xijun Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Anti-Inflammatory and Immunomodulatory Effects of Paeonia Lactiflora Pall., a Traditional Chinese Herbal Medicine

(2011) Dong-Yi He et al.   Frontiers in Pharmacology

A component of the medicinal herb ephedra blocks activation in the classical and alternative pathways of complement

(2010) M. LING et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Ephedrannin A and B from roots of Ephedra sinica inhibit lipopolysaccharide-induced inflammatory mediators by suppressing nuclear factor-κB activation in RAW 264.7 macrophages

(2010) Ik-Soo Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Proteomic Analysis of Anti-inflammatory Effects of a Kampo (Japanese Herbal) Medicine “Shoseiryuto (Xiao-Qing-Long-Tang)” on Airway Inflammation in a Mouse Model

(2009) Takayuki Nagai et al.   Evidence-based Complementary and Alternative Medicine

Ginkgo biloba for Preventing Cognitive Decline in Older AdultsA Randomized Trial

(2009) Beth E. Snitz   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Baicalin in Radical Scavenging and Its Synergistic Effect with β-Carotene in Antilipoxidation

(2009) Ran Liang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lead, Mercury, and Arsenic in US- and Indian-Manufactured Ayurvedic Medicines Sold via the Internet

(2008) Robert B. Saper   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interaction Between Warfarin and Panax ginseng in Ischemic Stroke Patients

(2008) Sang-Hun Lee et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

Nitrite oxide and inducible nitric oxide synthase were regulated by polysaccharides isolated from Glycyrrhiza uralensis Fisch

(2008) Anwei Cheng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE

Cinnamaldehyde inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling

(2007) Louis Kuoping Chao et al.   FOOD AND CHEMICAL TOXICOLOGY