Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice

Promotion of regulatory T cell induction by immunomodulatory herbal medicine licorice and its two constituents

(2015) Ao Guo et al.   Scientific Reports

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation

(2014) Hiroe Honda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis

(2014) Miyako Tanaka et al.   Nature Communications

Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis

(2014) Isabelle K. Vila et al.   Cell Reports

Dietary Compound Isoliquiritigenin Inhibits Breast Cancer Neoangiogenesis via VEGF/VEGFR-2 Signaling Pathway

(2013) Zhiyu Wang et al.   PLoS One

Involvement of Mincle and Syk in the changes to innate immunity after ischemic stroke

(2013) Yukiya Suzuki et al.   Scientific Reports

Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors

(2012) Marzena Ciechomska et al.   ANNALS OF THE RHEUMATIC DISEASES

The Radioprotective 105/MD-1 Complex Contributes to Diet-Induced Obesity and Adipose Tissue Inflammation

(2012) Yasuharu Watanabe et al.   DIABETES

Inflammation links excess fat to insulin resistance: the role of the interleukin-1 family

(2012) Cees J. Tack et al.   IMMUNOLOGICAL REVIEWS

Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A

(2012) N. Yamakawa et al.   INTERNATIONAL IMMUNOLOGY

Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll-like receptor 4/MD-2 complex signaling in a different manner

(2012) Hiroe Honda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells

(2011) Gang Chen et al.   APOPTOSIS

Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

(2011) Masayuki Ichioka et al.   DIABETES

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

The role of chalcones in suppression of NF-κB-mediated inflammation and cancer

(2010) Vivek R. Yadav et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C-type lectin Mincle is an activating receptor for pathogenic fungus,Malassezia

(2009) Sho Yamasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoliquiritigenin Inhibits Tumor Growth and Protects the Kidney and Liver Against Chemotherapy-Induced Toxicity in a Mouse Xenograft Model of Colon Carcinoma

(2008) Chang Ki Lee et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

(2008) T. Khan et al.   MOLECULAR AND CELLULAR BIOLOGY

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY