Conjugated Physiological Resveratrol Metabolites Induce Senescence in Breast Cancer Cells: Role of p53/p21 and p16/Rb Pathways, and ABC Transporters

Metabolic Profiling of Dietary Polyphenols and Methylxanthines in Normal and Malignant Mammary Tissues from Breast Cancer Patients

(2019) María Ángeles Ávila-Gálvez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol increases phagocytosis and lipopolysaccharide-induced interleukin-1β production, but decreases surface expression of Toll-like receptor 2 in THP-1 monocytes

(2018) Susan J. Zunino et al.   CYTOKINE

Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells

(2018) Shuhua Ji et al.   EXPERIMENTAL CELL RESEARCH

In Vitro Research on Dietary Polyphenols and Health: A Call of Caution and a Guide on How To Proceed

(2018) María Ángeles Ávila-Gálvez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Physiological relevance of the antiproliferative and estrogenic effects of dietary polyphenol aglycones versus their phase-II metabolites on breast cancer cells: A call of caution

(2018) María Ángeles Ávila-Gálvez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Phyto-polyphenols as potential inhibitors of breast cancer metastasis

(2018) Dimiter Avtanski et al.   MOLECULAR MEDICINE

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic–Mediating Machinery

(2018) Yifeng Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Extract from the Plant Deschampsia antarctica Protects Fibroblasts from Senescence Induced by Hydrogen Peroxide

(2017) Ana Ortiz-Espín et al.   Oxidative Medicine and Cellular Longevity

Potential miRNA involvement in the anti-adipogenic effect of resveratrol and its metabolites

(2017) Itziar Eseberri et al.   PLoS One

Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity

(2017) Anna Lewinska et al.   TOXICOLOGY LETTERS

Resveratrol-3-O-glucuronide and resveratrol-4′-O-glucuronide reduce DNA strand breakage but not apoptosis in Jurkat T cells treated with camptothecin

(2017) Susan J. Zunino et al.   Oncology Letters

Effects of bioactive compounds on senescence and components of senescence associated secretory phenotypes in vitro

(2017) Janubová Mária et al.   Food & Function

Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells

(2016) Antonio González-Sarrías et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Resveratrol improves the anticancer effects of doxorubicin in vitro and in vivo models: A mechanistic insight

(2016) Girish Rai et al.   PHYTOMEDICINE

Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms

(2016) Dona Sinha et al.   SEMINARS IN CANCER BIOLOGY

Hormesis does not make sense except in the light of TOR-driven aging

(2016) Mikhail V. Blagosklonny   Aging-US

Dietary patterns and breast cancer risk: a study in 2 cohorts

(2015) Chelsea Catsburg et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Senescence from G2 arrest, revisited

(2015) Véronique Gire et al.   CELL CYCLE

Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism

(2015) Antonio González-Sarrías et al.   EUROPEAN JOURNAL OF NUTRITION

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ColonyArea: An ImageJ Plugin to Automatically Quantify Colony Formation in Clonogenic Assays

(2014) Camilo Guzmán et al.   PLoS One

Resveratrol abrogates the Temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the Temozolomide-induced senescence in glioma cells

(2013) Eduardo C Filippi-Chiela et al.   BMC CANCER

Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence

(2013) Joao Tomé-Carneiro et al.   CURRENT PHARMACEUTICAL DESIGN

Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death

(2013) Virginie Aires et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol Induces Premature Senescence in Lung Cancer Cells via ROS-Mediated DNA Damage

(2013) Hongmei Luo et al.   PLoS One

Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence

(2013) K. R. Patel et al.   Science Translational Medicine

Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention

(2012) María Azorín-Ortuño et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cellular senescence and tumor suppressor gene p16

(2011) Hani Rayess et al.   INTERNATIONAL JOURNAL OF CANCER

Metabolites and tissue distribution of resveratrol in the pig

(2011) María Azorín-Ortuño et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Vascular deconjugation of quercetin glucuronide: The flavonoid paradox revealed?

(2011) Carmen Menendez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Disposition of soy isoflavones in normal human breast tissue

(2010) Selin Bolca et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Resveratrol commonly displays hormesis: Occurrence and biomedical significance

(2010) Edward J Calabrese et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Disposition of hop prenylflavonoids in human breast tissue

(2010) Selin Bolca et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols