Downregulation of 14-3-3 Proteins in Alzheimer’s Disease

Decreased Mcl-1 protein level in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice

(2018) Edward Lu et al.   BRAIN RESEARCH

Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model

(2017) Danyal Smani et al.   MOLECULAR NEUROBIOLOGY

Sex differences in Alzheimer's disease and other dementias

(2016) Carolyn M Mazure et al.   LANCET NEUROLOGY

Increased 14-3-3 phosphorylation observed in Parkinson's disease reduces neuroprotective potential of 14-3-3 proteins

(2015) Sunny Rae Slone et al.   NEUROBIOLOGY OF DISEASE

14-3-3 inhibition promotes dopaminergic neuron loss and 14-3-3θ overexpression promotes recovery in the MPTP mouse model of Parkinson’s disease

(2015) H. Ding et al.   NEUROSCIENCE

The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity

(2014) Nicoletta Plotegher et al.   HUMAN MOLECULAR GENETICS

Neuroprotective Effect of TAT-14-3-3ε Fusion Protein against Cerebral Ischemia/Reperfusion Injury in Rats

(2014) Yuanjun Zhu et al.   PLoS One

Interaction of 14-3-3ζ with Microtubule-Associated Protein Tau within Alzheimer’s Disease Neurofibrillary Tangles

(2013) Hamid Y. Qureshi et al.   BIOCHEMISTRY

Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo

(2013) Gary P. Brennan et al.   PLoS One

Neuroprotective Function of 14-3-3 Proteins in Neurodegeneration

(2013) Tadayuki Shimada et al.   Biomed Research International

14-3-3 Proteins are Regulators of Autophagy

(2012) Mercedes Pozuelo-Rubio   Cells

Differential Expression of 14-3-3 Isoforms in Human Alcoholic Brain

(2011) Rachel K. MacKay et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Differential expression of 14-3-3 protein isoforms in developing rat hippocampus, cortex, rostral migratory stream, olfactory bulb, and white matter

(2011) Takahiko Umahara et al.   BRAIN RESEARCH

14-3-3theta Protects against Neurotoxicity in a Cellular Parkinson's Disease Model through Inhibition of the Apoptotic Factor Bax

(2011) Sunny R. Slone et al.   PLoS One

14-3-3 proteins in neurodegeneration

(2011) Petra Steinacker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

14-3-3 proteins as signaling integration points for cell cycle control and apoptosis

(2011) Alexandra K. Gardino et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease

(2010) T A Yacoubian et al.   Cell Death & Disease

Differential interaction and aggregation of 3-repeat and 4-repeat tau isoforms with 14-3-3ζ protein

(2009) Golam Sadik et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ligand-Activated Peroxisome Proliferator–Activated Receptor-γ Protects Against Ischemic Cerebral Infarction and Neuronal Apoptosis by 14-3-3ε Upregulation

(2009) Jui-Sheng Wu et al.   CIRCULATION

Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes

(2009) Øyvind Halskau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

14-3-3ζ Contributes to Tyrosine Hydroxylase Activity in MN9D Cells

(2009) Jian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of 14-3-3 zeta elicits endoplasmic reticulum stress and cell death, and increases vulnerability to kainate-induced injury in mouse hippocampal cultures

(2008) Niamh Murphy et al.   JOURNAL OF NEUROCHEMISTRY