14-3-3 Proteins are Regulators of Autophagy

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Protein kinase C inhibits autophagy and phosphorylates LC3

(2010) Houbo Jiang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Bioinformatic and experimental survey of 14-3-3-binding sites

(2010) Catherine Johnson et al.   BIOCHEMICAL JOURNAL

p38 Mitogen-Activated Protein Kinase is Involved in Endoplasmic Reticulum Stress-Induced Cell Death and Autophagy in Human Gingival Fibroblasts

(2010) Do-Sung Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

mTORC1 signaling requires proteasomal function and the involvement of CUL4-DDB1 ubiquitin E3 ligase

(2010) Papia Ghosh et al.   CELL CYCLE

Regulation of autophagic activity by 14-3-3ζ proteins associated with class III phosphatidylinositol-3-kinase

(2010) M Pozuelo-Rubio   CELL DEATH AND DIFFERENTIATION

Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1

(2010) Emmani B.M. Nascimento et al.   CELLULAR SIGNALLING

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes

(2010) Mitsunori Miyazaki et al.   FEBS Journal

Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis

(2010) Mercedes Pozuelo-Rubio   FEBS Journal

New insights into the function of Atg9

(2010) Jemma L. Webber et al.   FEBS LETTERS

Resveratrol Arrests Cell Cycle and Induces Apoptosis in Human Hepatocellular Carcinoma Huh-7 Cells

(2010) Pei-Chi Liao et al.   JOURNAL OF MEDICINAL FOOD

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated Apoptosis

(2010) C.-H. Choi et al.   MOLECULAR PHARMACOLOGY

Triterpenes FromGanoderma LucidumInduce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK)

(2010) Anita Thyagarajan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cells

(2010) Sung-Chul Lim et al.   TOXICOLOGY

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

(2009) R. J. Shaw   Acta Physiologica

Targeting 14-3-3 protein, difopein induces apoptosis of human glioma cells and suppresses tumor growth in mice

(2009) Weidong Cao et al.   APOPTOSIS

Autophagy is an important event for megakaryocytic differentiation of the chronic myelogenous leukemia K562 cell line

(2009) Pascal Colosetti et al.   Autophagy

The cadmium-induced death of mesangial cells results in nephrotoxicity

(2009) Liang-Yo Yang et al.   Autophagy

Nutrient-dependent regulation of autophagy through the target of rapamycin pathway: Figure 1

(2009) Yu-Yun Chang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

14-3-3  Overexpression Defines High Risk for Breast Cancer Recurrence and Promotes Cancer Cell Survival

(2009) C. L. Neal et al.   CANCER RESEARCH

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

(2009) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The role of endoplasmic reticulum in cadmium-induced mesangial cell apoptosis

(2009) Sheng-Hao Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

(2009) Jemma L Webber et al.   EMBO JOURNAL

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

(2009) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy

(2009) Y. Kamada et al.   MOLECULAR AND CELLULAR BIOLOGY

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

FLIP-mediated autophagy regulation in cell death control

(2009) Jong-Soo Lee et al.   NATURE CELL BIOLOGY

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Proteomic profiling of tandem affinity purified 14-3-3 protein complexes inArabidopsis thaliana

(2009) Ing-Feng Chang et al.   PROTEOMICS

ERK and JNK mediate TNFα-induced p53 activation in apoptotic and autophagic L929 cell death

(2008) Yan Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The regulation and function of Class III PI3Ks: novel roles for Vps34

(2008) Jonathan M. Backer   BIOCHEMICAL JOURNAL

Proteomic Analysis of Bovine Sperm YWHA Binding Partners Identify Proteins Involved in Signaling and Metabolism1

(2008) Pawan Puri et al.   BIOLOGY OF REPRODUCTION

Hypoxia regulates TSC1/2 mTOR signaling and tumor suppression through REDD1-mediated 14 3 3 shuttling

(2008) M. P. DeYoung et al.   GENES & DEVELOPMENT

Novel Roles for Protein Kinase Cδ-dependent Signaling Pathways in Acute Hypoxic Stress-induced Autophagy

(2008) Jo-Lin Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Proline-rich Akt Substrate of 40 kDa (PRAS40) Function by Mammalian Target of Rapamycin Complex 1 (mTORC1)-mediated Phosphorylation

(2008) Lifu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase Cθ Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum

(2008) Kenjiro Sakaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

A Combined Proteome and Ultrastructural Localization Analysis of 14-3-3 Proteins in Transformed Human Amnion (AMA) Cells

(2008) José M. A. Moreira et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification of different isoforms of 14-3-3 protein family in human dermal and epidermal layers

(2008) Ruhangiz T. Kilani et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL