Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid‐predominant mouse model of Alzheimer's disease

Memantine ER Maintains Patient Response in Moderate to Severe Alzheimer’s Disease

(2018) George T. Grossberg et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Anti-inflammatory effects of Melatonin: a mechanistic review

(2018) Seyed Mohammad Nabavi et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Memantine reduces the production of amyloid-β peptides through modulation of amyloid precursor protein trafficking

(2017) Kaori Ito et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Melatonin ameliorates Aβ1-42 -induced Alzheimer's cognitive deficits in mouse model

(2017) Yu-Hang Gong et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume

(2016) Corinna Höfling et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease

(2016) G. D. Manocha et al.   JOURNAL OF NEUROSCIENCE

Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells

(2015) Jiraporn Panmanee et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and brain inflammaging

(2015) Rüdiger Hardeland et al.   PROGRESS IN NEUROBIOLOGY

Memantine Monotherapy for Alzheimer’s Disease: A Systematic Review and Meta-Analysis

(2015) Shinji Matsunaga et al.   PLoS One

Melatonin and oestrogen treatments were able to improve neuroinflammation and apoptotic processes in dentate gyrus of old ovariectomized female rats

(2014) Roman A. Kireev et al.   AGE

The role of inflammasome in Alzheimer's disease

(2014) Li Liu et al.   AGEING RESEARCH REVIEWS

Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

(2014) Andrea Crotti et al.   NATURE NEUROSCIENCE

Mechanism of synapse redox stress in Okadaic acid (ICV) induced memory impairment: Role of NMDA receptor

(2014) Pradip K. Kamat et al.   NEUROCHEMISTRY INTERNATIONAL

Current Pharmacologic Treatment of Dementia: A Clinical Practice Guideline from the American College of Physicians and the American Academy of Family Physicians

(2013) Amir Qaseem   ANNALS OF INTERNAL MEDICINE

TDP-43 frontotemporal lobar degeneration and autoimmune disease

(2013) Z. A. Miller et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model

(2013) Cai-Xia Peng et al.   NEUROBIOLOGY OF AGING

Microglia as Dynamic and Essential Components of the Amyloid Hypothesis

(2013) Sam Gandy et al.   NEURON

Effects of memantine and melatonin on signal transduction pathways vascular leakage and brain injury after focal cerebral ischemia in mice

(2013) U. Kilic et al.   NEUROSCIENCE

Deregulated Cdk5 Activity Is Involved in Inducing Alzheimer’s Disease

(2012) Varsha Shukla et al.   ARCHIVES OF MEDICAL RESEARCH

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

Diosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice

(2012) Chihiro Tohda et al.   Scientific Reports

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

(2011) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Protection from Glutamate-Induced Excitotoxicity by Memantine

(2011) Melinda K. Kutzing et al.   ANNALS OF BIOMEDICAL ENGINEERING

Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin

(2011) Sergio A. Rosales-Corral et al.   JOURNAL OF PINEAL RESEARCH

Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer’s disease

(2011) Mohammed Filali et al.   NEUROPHARMACOLOGY

Mechanism of neuroprotection of melatonin against beta-amyloid neurotoxicity

(2011) M. Ionov et al.   NEUROSCIENCE

Antiinflammatory Activity of Melatonin in Central Nervous System

(2010) Emanuela Esposito et al.   Current Neuropharmacology

Memantine ER, a once-daily formulation for the treatment of Alzheimer's disease

(2010) Nazem Bassil et al.   EXPERT OPINION ON PHARMACOTHERAPY

Behavioral profile of mice with impaired cognition in the elevated plus-maze due to a deficiency in neural cell adhesion molecule

(2010) M. Jürgenson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Memantine Improves Cognition and Reduces Alzheimer’s-Like Neuropathology in Transgenic Mice

(2009) Hilda Martinez-Coria et al.   AMERICAN JOURNAL OF PATHOLOGY

Recent developments in Alzheimer's disease therapeutics

(2009) Michael S Rafii et al.   BMC Medicine

Memantine lowers amyloid-β peptide levels in neuronal cultures and in APP/PS1 transgenic mice

(2009) George M. Alley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease

(2009) James M. Olcese et al.   JOURNAL OF PINEAL RESEARCH

Melatonin formation in mammals: In vivo perspectives

(2009) Asamanja Chattoraj et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Spondylocheiro Dysplastic Form of the Ehlers-Danlos Syndrome—An Autosomal-Recessive Entity Caused by Mutations in the Zinc Transporter Gene SLC39A13

(2008) Cecilia Giunta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Memantine leads to behavioral improvement and amyloid reduction in Alzheimer's-disease-model transgenic mice shown as by micromagnetic resonance imaging

(2008) Henrieta Scholtzova et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species

(2008) Fabienne Peyrot et al.   JOURNAL OF PINEAL RESEARCH

Melatonin is able to prevent the liver of old castrated female rats from oxidative and pro-inflammatory damage

(2008) R. A. Kireev et al.   JOURNAL OF PINEAL RESEARCH

Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model

(2008) Ryoichi Kimura et al.   NEUROBIOLOGY OF DISEASE

Effects of Memantine on Neuronal Structure and Conditioned Fear in the Tg2576 Mouse Model of Alzheimer's Disease

(2008) Hongxin Dong et al.   NEUROPSYCHOPHARMACOLOGY

Impaired Spatial Learning Strategies and Novel Object Recognition in Mice Haploinsufficient for the Dual Specificity Tyrosine-Regulated Kinase-1A (Dyrk1A)

(2008) Glòria Arqué et al.   PLoS One