Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces

(2014) Russel J. Reiter et al.   Brain Structure & Function

Melatonin from Cerebrospinal Fluid but Not from Blood Reaches Sheep Cerebral Tissues Under Physiological Conditions

(2014) C. Legros et al.   JOURNAL OF NEUROENDOCRINOLOGY

Melatonin stimulates the nonamyloidogenic processing ofβAPP through the positive transcriptional regulation of ADAM10 and ADAM17

(2014) Mayuri Shukla et al.   JOURNAL OF PINEAL RESEARCH

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

(2014) Joaquín J. García et al.   JOURNAL OF PINEAL RESEARCH

Melatonin: a well-documented antioxidant with conditional pro-oxidant actions

(2014) Hong-Mei Zhang et al.   JOURNAL OF PINEAL RESEARCH

Trientine Reduces BACE1 Activity and Mitigates Amyloidosis via the AGE/RAGE/NF-κB Pathway in a Transgenic Mouse Model of Alzheimer's Disease

(2013) Chun-Yan Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Melatonin in Alzheimer’s Disease

(2013) Li Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

AZ-4217: A High Potency BACE Inhibitor Displaying Acute Central Efficacy in Different In Vivo Models and Reduced Amyloid Deposition in Tg2576 Mice

(2013) S. Eketjall et al.   JOURNAL OF NEUROSCIENCE

Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model

(2013) Cai-Xia Peng et al.   NEUROBIOLOGY OF AGING

1-Methyl-4-Phenylpyridinium-Induced Cell Death via Autophagy Through a Bcl-2/Beclin 1 Complex-Dependent Pathway

(2013) Chutikorn Nopparat et al.   NEUROCHEMICAL RESEARCH

Melatonin protects against amyloid-β-induced impairments of hippocampal LTP and spatial learning in rats

(2013) Xiao-Jie Liu et al.   SYNAPSE

Melatonin can improve insulin resistance and aging-induced pancreas alterations in senescence-accelerated prone male mice (SAMP8)

(2012) Sara Cuesta et al.   AGE

BACE1 in Alzheimer's disease

(2012) M. Sathya et al.   CLINICA CHIMICA ACTA

Nuclear Factor-κB Regulates βAPP and β- and γ-Secretases Differently at Physiological and Supraphysiological Aβ Concentrations

(2012) Linda Chami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

(2012) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

The Anti-inflammatory Effect of Melatonin on Methamphetamine-Induced Proinflammatory Mediators in Human Neuroblastoma Dopamine SH-SY5Y Cell Lines

(2012) Kannika Permpoonputtana et al.   NEUROTOXICITY RESEARCH

Age-dependent Accumulation of Soluble Amyloid β (Aβ) Oligomers Reverses the Neuroprotective Effect of Soluble Amyloid Precursor Protein-α (sAPPα) by Modulating Phosphatidylinositol 3-Kinase (PI3K)/Akt-GSK-3β Pathway in Alzheimer Mouse Model

(2011) Sebastian Jimenez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin reduces hippocampal β-amyloid generation in rats exposed to chronic intermittent hypoxia

(2010) Kwong-Man Ng et al.   BRAIN RESEARCH

Anti-Amyloidogenic and Anti-Apoptotic Role of Melatonin in Alzheimer Disease

(2010) Hongwen He et al.   Current Neuropharmacology

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease

(2010) Oyinkan Sofola et al.   PLoS Genetics

Anti-aging properties of melatonin in an in vitro murine senescence model: involvement of the sirtuin 1 pathway

(2009) M. Tajes et al.   JOURNAL OF PINEAL RESEARCH

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease

(2009) Alessio Colombo et al.   NEUROBIOLOGY OF DISEASE

NFκB-dependent Control ofBACE1Promoter Transactivation by Aβ42

(2008) Virginie Buggia-Prevot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of potential pro-survival pathways regulated by melatonin in a murine senescence model

(2008) Javier Gutierrez-Cuesta et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents amyloid protofibrillar induced oxidative imbalance and biogenic amine catabolism

(2008) Masilamoni J. Gunasingh et al.   LIFE SCIENCES

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Effect of Melatonin and Melatonylvalpromide on β-amyloid and Neurofilaments in N2a Cells

(2008) Xiao-Chuan Wang et al.   NEUROCHEMICAL RESEARCH

Melatonin inhibits amphetamine-induced increase in α-synuclein and decrease in phosphorylated tyrosine hydroxylase in SK–N–SH cells

(2008) Sirirat Klongpanichapak et al.   NEUROSCIENCE LETTERS