The central role of the tail in switching off 10S myosin II activity

CryoEM Single Particle Reconstruction of Dephosphorylated HMM from Smooth Muscle

(2019) Alimohammad Hojjatian   BIOPHYSICAL JOURNAL

Mammalian nonmuscle myosin II comes in three flavors

(2018) Maria S. Shutova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals

(2018) Kyoung Hwan Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

(2017) Suman Nag et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II

(2017) Xiong Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

(2017) Suman Nag et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis

(2016) Lorenzo Alamo et al.   JOURNAL OF MOLECULAR BIOLOGY

An approach to improve the resolution of helical filaments with a large axial rise and flexible subunits

(2016) Shixin Yang et al.   JOURNAL OF STRUCTURAL BIOLOGY

While the revolution will not be crystallized, biochemistry reigns supreme

(2016) Yoshimasa Takizawa et al.   PROTEIN SCIENCE

The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy

(2015) James A. Spudich   BIOCHEMICAL SOCIETY TRANSACTIONS

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

(2015) K. A. Newell-Litwa et al.   Disease Models & Mechanisms

The structure of the dynactin complex and its interaction with dynein

(2015) L. Urnavicius et al.   SCIENCE

Role of the essential light chain in the activation of smooth muscle myosin by regulatory light chain phosphorylation

(2013) Kenneth A. Taylor et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural basis of the relaxed state of a Ca2+-regulated myosin filament and its evolutionary implications

(2013) J. L. Woodhead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosinopathies: pathology and mechanisms

(2012) Homa Tajsharghi et al.   ACTA NEUROPATHOLOGICA

Understanding Cardiomyopathy Phenotypes Based on the Functional Impact of Mutations in the Myosin Motor

(2012) Jeffrey R. Moore et al.   CIRCULATION RESEARCH

Nonmuscle myosin II folds into a 10S form via two portions of tail for dynamic subcellular localization

(2012) Takayuki Kiboku et al.   GENES TO CELLS

The myosin interacting-heads motif is present in the relaxed thick filament of the striated muscle of scorpion

(2012) Antonio Pinto et al.   JOURNAL OF STRUCTURAL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Role of the Tail in the Regulated State of Myosin 2

(2011) Hyun Suk Jung et al.   JOURNAL OF MOLECULAR BIOLOGY

A Molecular Model of Phosphorylation-Based Activation and Potentiation of Tarantula Muscle Thick Filaments

(2011) Reicy Brito et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells

(2011) D. L. Milton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smooth Muscle Heavy Meromyosin Phosphorylated on One of Its Two Heads Supports Force and Motion

(2009) Sam Walcott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myosin ATP turnover rate is a mechanism involved in thermogenesis in resting skeletal muscle fibers

(2009) M. A. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate Myosin Activity

(2008) Lorenzo Alamo et al.   JOURNAL OF MOLECULAR BIOLOGY

Head–Head Interaction Characterizes the Relaxed State of Limulus Muscle Myosin Filaments

(2008) Fa-Qing Zhao et al.   JOURNAL OF MOLECULAR BIOLOGY

Thermodynamic and Structural Basis of Phosphorylation-Induced Disorder-to-Order Transition in the Regulatory Light Chain of Smooth Muscle Myosin

(2008) L. Michel Espinoza-Fonseca et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Head–Head and Head–Tail Interaction: A General Mechanism for Switching Off Myosin II Activity in Cells

(2008) Hyun Suk Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Multiple Regulatory Steps Control Mammalian Nonmuscle Myosin II Assembly in Live Cells

(2008) Mark T. Breckenridge et al.   MOLECULAR BIOLOGY OF THE CELL

Conservation of the regulated structure of folded myosin 2 in species separated by at least 600 million years of independent evolution

(2008) H. S. Jung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional structure of vertebrate cardiac muscle myosin filaments

(2008) M. E. Zoghbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Unstable Head–Rod Junction May Promote Folding into the Compact Off-State Conformation of Regulated Myosins

(2007) Jerry H. Brown et al.   JOURNAL OF MOLECULAR BIOLOGY