The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy

Altered interactions between cardiac myosin binding protein-c and α-cardiac actin variants associated with cardiomyopathies

(2014) Melissa L. Chow et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Hypertrophic and Dilated Cardiomyopathy: Four Decades of Basic Research on Muscle Lead to Potential Therapeutic Approaches to These Devastating Genetic Diseases

(2014) James A. Spudich   BIOPHYSICAL JOURNAL

The landscape of genetic variation in dilated cardiomyopathy as surveyed by clinical DNA sequencing

(2014) Trevor J. Pugh et al.   GENETICS IN MEDICINE

Earning stripes: myosin binding protein-C interactions with actin

(2014) Sabine J. van Dijk et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells

(2014) Thomas Kampourakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac Structural and Sarcomere Genes Associated With Cardiomyopathy Exhibit Marked Intolerance of Genetic Variation

(2012) Stephen Pan et al.   Circulation-Cardiovascular Genetics

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

(2012) Mark Pfuhl et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

One path to understanding energy transduction in biological systems

(2012) James A Spudich   NATURE MEDICINE

Identifying Sarcomere Gene Mutations in Hypertrophic Cardiomyopathy

(2011) Christine E. Seidman et al.   CIRCULATION RESEARCH

Structure and Interactions of Myosin-binding Protein C Domain C0

(2011) Joyce Ratti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular mechanisms of cardiomyopathy

(2011) Pamela A. Harvey et al.   JOURNAL OF CELL BIOLOGY

Molecular motors: forty years of interdisciplinary research

(2011) James A. Spudich   MOLECULAR BIOLOGY OF THE CELL

Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure

(2011) F. I. Malik et al.   SCIENCE

Structural and Functional Insights into the Myosin Motor Mechanism

(2010) H. Lee Sweeney et al.   Annual Review of Biophysics

Binding of the N-terminal fragment C0–C2 of cardiac MyBP-C to cardiac F-actin

(2010) Robert W. Kensler et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cardiomyopathy: A Systematic Review of Disease-Causing Mutations in Myosin Heavy Chain 7 and Their Phenotypic Manifestations

(2009) R. Walsh et al.   CARDIOLOGY

Actin, a Central Player in Cell Shape and Movement

(2009) T. D. Pollard et al.   SCIENCE

Bioinformatics Assessment of β-Myosin Mutations Reveals Myosin's High Sensitivity to Mutations

(2008) Massimo Buvoli et al.   TRENDS IN CARDIOVASCULAR MEDICINE