P53-R273H mutation enhances colorectal cancer stemness through regulating specific lncRNAs

Non-coding RNAs in cancer stem cells

(2018) Huiwen Yan et al.   CANCER LETTERS

The Canonical Wnt Pathway Drives Macropinocytosis in Cancer

(2018) Gil Redelman-Sidi et al.   CANCER RESEARCH

Functional Classification and Experimental Dissection of Long Noncoding RNAs

(2018) Florian Kopp et al.   CELL

Long Non-Coding RNA SH3PXD2A-AS1 Promotes Cell Progression Partly Through Epigenetic Silencing P57 and KLF2 in Colorectal Cancer

(2018) Zhonghua Ma et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1

(2018) Mengmeng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability

(2018) Wang Lai Hu et al.   NATURE CELL BIOLOGY

Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19

(2018) Jing Ren et al.   Theranostics

Oncogene c-fos and mutant R175H p53 regulate expression of Nucleophosmin implicating cancer manifestation

(2018) Parijat Senapati et al.   FEBS Journal

The roles of ZEB1 in tumorigenic progression and epigenetic modifications

(2018) Yu Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation

(2017) Su Yeon Lee et al.   Molecular Cancer

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer

(2017) Akshay Malhotra et al.   Oncotarget

ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

(2016) Waltraut Lehmann et al.   Nature Communications

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells

(2016) Salman B. Hosain et al.   Oncotarget

UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1

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Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance

(2015) Niels F. Jensen et al.   Molecular Oncology

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

Targeting Oncogenic Mutant p53 for Cancer Therapy

(2015) Alejandro Parrales et al.   Frontiers in Oncology

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

(2014) A. P. Patel et al.   SCIENCE

Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature

(2014) Yolanda Sánchez et al.   Nature Communications

In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies

(2014) Martina McDermott et al.   Frontiers in Oncology

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Epithelial-Mesenchymal Transition and Tumor Suppression Are Controlled by a Reciprocal Feedback Loop between ZEB1 and Grainyhead-like-2

(2013) B. Cieply et al.   CANCER RESEARCH

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

(2013) W Hanel et al.   CELL DEATH AND DIFFERENTIATION

Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis in patients with colorectal cancer

(2013) Xiaosong Ge et al.   MEDICAL ONCOLOGY

Epithelial-Mesenchymal Transition Associates with Maintenance of Stemness in Spheroid-Derived Stem-Like Colon Cancer Cells

(2013) Xiao-Yan Han et al.   PLoS One

Acquisition of epithelial–mesenchymal transition and cancer stem cell phenotypes is associated with activation of the PI3K/Akt/mTOR pathway in prostate cancer radioresistance

(2013) L Chang et al.   Cell Death & Disease

EMT and MET in Metastasis: Where Are the Cancer Stem Cells?

(2012) Thomas Brabletz   CANCER CELL

Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity

(2012) Timo Quante et al.   CELL CYCLE

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

The dimensions of the CRC problem

(2010) L.v. Karsa et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis

(2008) Ryan Lister et al.   CELL

Stem cell transcriptome profiling via massive-scale mRNA sequencing

(2008) Nicole Cloonan et al.   NATURE METHODS

Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies

(2008) Xiaodong Zhang et al.   NATURE METHODS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY