WNT1‐inducible signaling protein‐1 mediates TGF‐β1‐induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy

Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β 1/Smads pathway through shikonin

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Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

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TGF-β: the master regulator of fibrosis

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KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways

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Experimental research Blockade of CCN4 attenuates CCl 4 -induced liver fibrosis

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CCN4/WISP1 (WNT1 inducible signaling pathway protein 1): A focus on its role in cancer

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Autophagy is a regulator of TGF-β1-induced fibrogenesis in primary human atrial myofibroblasts

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WNT-1 inducible signaling pathway protein-1 enhances growth and tumorigenesis in human breast cancer

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TGF-β/Smad signaling in renal fibrosis

(2015) Xiao-Ming Meng et al.   Frontiers in Physiology

Lipidation of the autophagy proteins LC3 and GABARAP is a membrane-curvature dependent process

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WISP 1 is an important survival factor in human mesenchymal stromal cells

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Autophagy Regulates TGF-  Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction

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Autophagy: A Multifaceted Partner in Liver Fibrosis

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Wnt/β-catenin signaling and kidney fibrosis

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The ER-Golgi intermediate compartment feeds the phagophore membrane

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Autophagy and apoptosis in tubular cells following unilateral ureteral obstruction are associated with mitochondrial oxidative stress

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The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway

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CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts

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Insufficient autophagy in idiopathic pulmonary fibrosis

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WISP1 (CCN4) Autoregulates its Expression and Nuclear Trafficking of β-Catenin during Oxidant Stress with Limited Effects upon Neuronal Autophagy

(2012) Shaohui Wang et al.   CURRENT NEUROVASCULAR RESEARCH

Targeting disease through novel pathways of apoptosis and autophagy

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Autophagy Releases Lipid That Promotes Fibrogenesis by Activated Hepatic Stellate Cells in Mice and in Human Tissues

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Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation

(2012) Hui Yao Lan   International Journal of Biological Sciences

Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1

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The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

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Mechanisms of fibrosis: therapeutic translation for fibrotic disease

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Selective autophagy mediated by autophagic adapter proteins

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GABARAPL1 Negatively Regulates Wnt/β-catenin Signaling by Mediating Dvl2 Degradation through the Autophagy Pathway

(2011) Yanquan Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A role for autophagy during hepatic stellate cell activation

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Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro

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Targeted Inhibition of  -Catenin/CBP Signaling Ameliorates Renal Interstitial Fibrosis

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Smad3-Mediated Upregulation of miR-21 Promotes Renal Fibrosis

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The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

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(2011) Youhua Liu   Nature Reviews Nephrology

The role of autophagy in unilateral ureteral obstruction rat model

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Investigating mechanisms of chronic kidney disease in mouse models

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Autophagy Is a Component of Epithelial Cell Fate in Obstructive Uropathy

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Tubular Overexpression of Transforming Growth Factor-β1 Induces Autophagy and Fibrosis but Not Mesenchymal Transition of Renal Epithelial Cells

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Wnt/β-catenin signaling: A novel target for therapeutic intervention of fibrotic kidney disease

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Methods in Mammalian Autophagy Research

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Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

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WNT1 inducible signaling pathway protein 1 (WISP1): A novel mediator linking development and disease

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Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Smad2 Protects against TGF- /Smad3-Mediated Renal Fibrosis

(2010) X. M. Meng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal fibrosis: novel insights into mechanisms and therapeutic targets

(2010) Peter Boor et al.   Nature Reviews Nephrology

WISP1, a Pro-mitogenic, Pro-survival Factor, Mediates Tumor Necrosis Factor-α (TNF-α)-stimulated Cardiac Fibroblast Proliferation but Inhibits TNF-α-induced Cardiomyocyte Death

(2009) Kaliyamurthi Venkatachalam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt/ -Catenin Signaling Promotes Renal Interstitial Fibrosis

(2009) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Latent TGF- 1 Protects Against Crescentic Glomerulonephritis

(2008) X. R. Huang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY