Deacetylation of LAMP1 drives lipophagy‐dependent generation of free fatty acids by Abrus agglutinin to promote senescence in prostate cancer

PUMA dependent mitophagy by Abrus agglutinin contributes to apoptosis through ceramide generation

(2018) Prashanta Kumar Panda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Punicalagin induces senescent growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway

(2018) Xian Cheng et al.   BIOMEDICINE & PHARMACOTHERAPY

Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells

(2018) Karthikeyan Subburayan et al.   CANCER LETTERS

Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress

(2018) Yi-Chieh Yang et al.   CANCER LETTERS

Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells

(2018) Prashanta K. Panda et al.   MOLECULAR CARCINOGENESIS

A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma

(2018) Zhi-qiang Yao et al.   Cell Death & Disease

Role of P53-Senescence Induction in Suppression of LNCaP Prostate Cancer Growth by Cardiotonic Compound Bufalin

(2018) Yong Zhang et al.   MOLECULAR CANCER THERAPEUTICS

ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway

(2017) Subhadip Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation

(2017) Thomas Riffelmacher et al.   IMMUNITY

Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma

(2017) Niharika Sinha et al.   MOLECULAR CARCINOGENESIS

Abrus agglutinin targets cancer stem-like cells by eliminating self-renewal capacity accompanied with apoptosis in oral squamous cell carcinoma

(2017) Niharika Sinha et al.   TUMOR BIOLOGY

AbrusAgglutinin, a type II ribosome inactivating protein inhibits Akt/PH domain to induce endoplasmic reticulum stress mediated autophagy-dependent cell death

(2016) Prashanta Kumar Panda et al.   MOLECULAR CARCINOGENESIS

Implications of cancer stem cells in developing therapeutic resistance in oral cancer

(2016) Prajna Paramita Naik et al.   ORAL ONCOLOGY

Galangin Induces Autophagy via Deacetylation of LC3 by SIRT1 in HepG2 Cells

(2016) Xv Li et al.   Scientific Reports

Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury

(2015) Tomoaki Koga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation

(2015) Rui Huang et al.   MOLECULAR CELL

Mechanism of autophagic regulation in carcinogenesis and cancer therapeutics

(2015) Prashanta Kumar Panda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation

(2015) Hussain El Hasasna et al.   Scientific Reports

Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase-mediated cell death

(2014) Subhadip Mukhopadhyay et al.   ACTA PHARMACOLOGICA SINICA

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells

(2014) Yao-Huei Huang et al.   Autophagy

SIRT1 Positively Regulates Autophagy and Mitochondria Function in Embryonic Stem Cells Under Oxidative Stress

(2014) Xuan Ou et al.   STEM CELLS

Lysosome: regulator of lipid degradation pathways

(2014) Carmine Settembre et al.   TRENDS IN CELL BIOLOGY

In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death

(2013) Subhadip Mukhopadhyay et al.   FOOD AND CHEMICAL TOXICOLOGY

Autophagy and senescence in cancer therapy

(2013) David A. Gewirtz   JOURNAL OF CELLULAR PHYSIOLOGY

Structural and Functional Analysis of Human SIRT1

(2013) Andrew M. Davenport et al.   JOURNAL OF MOLECULAR BIOLOGY

Pseudolaric Acid B^|^ndash;Induced Autophagy Contributes to Senescence via Enhancement of ROS Generation and Mitochondrial Dysfunction in Murine Fibrosarcoma L929 Cells

(2013) Min Qi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Sulfate Metabolites Provide an Intracellular Pool for Resveratrol Generation and Induce Autophagy with Senescence

(2013) K. R. Patel et al.   Science Translational Medicine

Dietary Resveratrol Prevents Development of High-Grade Prostatic Intraepithelial Neoplastic Lesions: Involvement of SIRT1/S6K Axis

(2012) G. Li et al.   Cancer Prevention Research

Senescence; an endogenous anticancer mechanism

(2012) Jose Vargas   Frontiers in Bioscience-Landmark

Aberrant Cytoplasm Localization and Protein Stability of SIRT1 is Regulated by PI3K/IGF-1R Signaling in Human Cancer Cells

(2012) Vanessa Byles et al.   International Journal of Biological Sciences

Sirtuin 1 in malignant transformation: Friend or foe?

(2011) Yujiang Fang et al.   CANCER LETTERS

SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions

(2009) Tong Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

In vitro immunostimulatory properties of Abrus lectins derived peptides in tumor bearing mice

(2009) Sujit K. Bhutia et al.   PHYTOMEDICINE

Accelerated senescence: An emerging role in tumor cell response to chemotherapy and radiation

(2008) David A. Gewirtz et al.   BIOCHEMICAL PHARMACOLOGY

Fatty acids as modulators of the cellular production of reactive oxygen species

(2008) Peter Schönfeld et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stimulation of murine B and T lymphocytes by native and heat-denatured Abrus agglutinin

(2008) Dipanjan Ghosh et al.   IMMUNOBIOLOGY