Abrus agglutinin promotes irreparable DNA damage by triggering ROS generation followed by ATM-p73 mediated apoptosis in oral squamous cell carcinoma

Abrus agglutinin is a potent anti-proliferative and anti-angiogenic agent in human breast cancer

(2016) Sujit K. Bhutia et al.   INTERNATIONAL JOURNAL OF CANCER

Autophagy protein Ulk1 promotes mitochondrial apoptosis through reactive oxygen species

(2015) Subhadip Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

p73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

(2015) J S Long et al.   ONCOGENE

Do high-risk human papillomaviruses cause oral cavity squamous cell carcinoma?

(2015) H. Mirghani et al.   ORAL ONCOLOGY

Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase-mediated cell death

(2014) Subhadip Mukhopadhyay et al.   ACTA PHARMACOLOGICA SINICA

Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy

(2014) Q.-L. Jiang et al.   CELL PROLIFERATION

Plant natural products: from traditional compounds to new emerging drugs in cancer therapy

(2014) L. Ouyang et al.   CELL PROLIFERATION

A review of Indian literature for association of smokeless tobacco with malignant and premalignant diseases of head and neck region

(2014) S Datta et al.   INDIAN JOURNAL OF CANCER

Antitumor effect of soybean lectin mediated through reactive oxygen species-dependent pathway

(2014) Prashanta Kumar Panda et al.   LIFE SCIENCES

A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression

(2014) D Engelmann et al.   ONCOGENE

Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin-Induced Apoptosis

(2014) Ritu Mishra et al.   PLoS One

In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death

(2013) Subhadip Mukhopadhyay et al.   FOOD AND CHEMICAL TOXICOLOGY

mda-7/IL-24 Differentially Regulates Soluble and Nuclear Clusterin in Prostate Cancer

(2013) Sujit K. Bhutia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer

(2013) Niharika Sinha et al.   ORAL ONCOLOGY

Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells

(2012) S. Shrotriya et al.   CARCINOGENESIS

Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73

(2010) Su Wei Wong et al.   BREAST CANCER RESEARCH AND TREATMENT

Induction of apoptosis by Concanavalin A and its molecular mechanisms in cancer cells

(2009) Bo Liu et al.   Autophagy

Abrus abrin derived peptides induce apoptosis by targeting mitochondria in HeLa cells

(2009) Sujit K. Bhutia et al.   CELL BIOLOGY INTERNATIONAL

In vitro immunostimulatory properties of Abrus lectins derived peptides in tumor bearing mice

(2009) Sujit K. Bhutia et al.   PHYTOMEDICINE

Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model

(2008) Sujit K. Bhutia et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Liposome-Encapsulated Curcumin Suppresses Growth of Head and Neck Squamous Cell Carcinoma In vitro and in Xenografts through the Inhibition of Nuclear Factor  B by an AKT-Independent Pathway

(2008) D. Wang et al.   CLINICAL CANCER RESEARCH

Stimulation of murine B and T lymphocytes by native and heat-denatured Abrus agglutinin

(2008) Dipanjan Ghosh et al.   IMMUNOBIOLOGY

Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway

(2008) J. E. Kravchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abrin induced oxidative stress mediated DNA damage in human leukemic cells and its reversal by N-acetylcysteine

(2008) A.S.B. Bhaskar et al.   TOXICOLOGY IN VITRO

Induction of mitochondria-dependent apoptosis by Abrus agglutinin derived peptides in human cervical cancer cell

(2007) Sujit K. Bhutia et al.   TOXICOLOGY IN VITRO