Metal binding to the amyloid-β peptides in the presence of biomembranes: potential mechanisms of cell toxicity

Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin)

(2019) Xiaolin Dong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Native Ion Mobility-Mass Spectrometry reveals the formation of β-barrel shaped Amyloid-β hexamers in a membrane-mimicking environment

(2019) Nicklas Österlund et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amyloid-β Peptide Interactions with Amphiphilic Surfactants: Electrostatic and Hydrophobic Effects

(2018) Nicklas Österlund et al.   ACS Chemical Neuroscience

Early events in copper-ion catalyzed oxidation of α-synuclein

(2018) Manish K. Tiwari et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alzheimer’s Amyloid-β is an Antimicrobial Peptide: A Review of the Evidence

(2018) Maya L. Gosztyla et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

The antimicrobial protection hypothesis of Alzheimer's disease

(2018) Robert D. Moir et al.   Alzheimers & Dementia

Membrane-mimetic systems for biophysical studies of the amyloid-β peptide

(2018) Nicklas Österlund et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Oxidative Stress, Synaptic Dysfunction, and Alzheimer’s Disease

(2017) Eric Tönnies et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer’s disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation

(2017) Cecilia Wallin et al.   Scientific Reports

Interaction of Aβ1–42 peptide or their variant with model membrane of different composition probed by infrared nanospectroscopy

(2017) S. Henry et al.   Nanoscale

Stabilization of native amyloid β-protein oligomers by Copper and Hydrogen peroxide Induced Cross-linking of Unmodified Proteins (CHICUP)

(2016) Thomas L. Williams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

The Amyloid-β Peptide in Amyloid Formation Processes: Interactions with Blood Proteins and Naturally Occurring Metal Ions

(2016) Cecilia Wallin et al.   ISRAEL JOURNAL OF CHEMISTRY

Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species

(2016) Ann Tiiman et al.   JOURNAL OF ALZHEIMERS DISEASE

Ion Channel Formation by Amyloid-β42Oligomers but Not Amyloid-β40in Cellular Membranes

(2016) David C. Bode et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the amyloid β peptide with sodium dodecyl sulfate as a membrane-mimicking detergent

(2016) Maryam Hashemi Shabestari et al.   JOURNAL OF BIOLOGICAL PHYSICS

Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer⿿s disease

(2016) Cecilia Wallin et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments

(2016) Montserrat Serra-Batiste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease

(2016) Youssra K. Al-Hilaly et al.   Scientific Reports

Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation

(2015) Axel Abelein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bexarotene Blocks Calcium-Permeable Ion Channels Formed by Neurotoxic Alzheimer’s β-Amyloid Peptides

(2014) Jacques Fantini et al.   ACS Chemical Neuroscience

Endogenous Polyamines Reduce the Toxicity of Soluble Aβ Peptide Aggregates Associated with Alzheimer’s Disease

(2014) Jinghui Luo et al.   BIOMACROMOLECULES

Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease

(2014) Samuel A. Kotler et al.   CHEMICAL SOCIETY REVIEWS

The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway

(2014) Axel Abelein et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Cellular Polyamines Promote Amyloid-Beta (Aβ) Peptide Fibrillation and Modulate the Aggregation Pathways

(2013) Jinghui Luo et al.   ACS Chemical Neuroscience

Biophysical Studies of the Amyloid β-Peptide: Interactions with Metal Ions and Small Molecules

(2013) Sebastian Wärmländer et al.   CHEMBIOCHEM

Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide

(2013) Jeffrey R. Brender et al.   CHEMICAL COMMUNICATIONS

Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide

(2013) Peter Faller et al.   INORGANIC CHEMISTRY

The missing link in the amyloid cascade of Alzheimer’s disease – Metal ions

(2013) Ann Tiiman et al.   NEUROCHEMISTRY INTERNATIONAL

Cu2+ Affects Amyloid-β (1–42) Aggregation by Increasing Peptide-Peptide Binding Forces

(2013) Francis Hane et al.   PLoS One

Synthetic dityrosine-linked β-amyloid dimers form stable, soluble, neurotoxic oligomers

(2013) W. Mei Kok et al.   Chemical Science

A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease

(2013) Youssra K Al-Hilaly et al.   Acta Neuropathologica Communications

Ca2+enhances Aβ polymerization rate and fibrillar stability in a dynamic manner

(2012) Kristoffer Brännström et al.   BIOCHEMICAL JOURNAL

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

Metal binding sites in amyloid oligomers: Complexes and mechanisms

(2012) Yifat Miller et al.   COORDINATION CHEMISTRY REVIEWS

Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals

(2012) Claudio D. Borsarelli et al.   FREE RADICAL BIOLOGY AND MEDICINE

Engineered non-fluorescent Affibody molecules facilitate studies of the amyloid-beta (Aβ) peptide in monomeric form: Low pH was found to reduce Aβ/Cu(II) binding affinity

(2012) Joel Lindgren et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Reevaluation of Copper(I) Affinity for Amyloid-β Peptides by Competition with Ferrozine-An Unusual Copper(I) Indicator

(2011) Bruno Alies et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iron(II) Binding to Amyloid-β, the Alzheimer’s Peptide

(2011) Fatima Bousejra-ElGarah et al.   INORGANIC CHEMISTRY

Single-channel Ca2+imaging implicates Aβ1–42 amyloid pores in Alzheimer’s disease pathology

(2011) Angelo Demuro et al.   JOURNAL OF CELL BIOLOGY

Physiological cholesterol concentration is a neuroprotective factor against β-amyloid and β-amyloid–metal complexes toxicity

(2011) A. Granzotto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cerebrospinal fluid/plasma quotients of essential and non-essential metals in patients with Alzheimer’s disease

(2011) Lars Gerhardsson et al.   JOURNAL OF NEURAL TRANSMISSION

Copper(II) Coordination to Amyloid β: Murine versus Human Peptide

(2010) Hélène Eury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Retardation of Aβ Fibril Formation by Phospholipid Vesicles Depends on Membrane Phase Behavior

(2010) Erik Hellstrand et al.   BIOPHYSICAL JOURNAL

Calcium Signaling and Amyloid Toxicity in Alzheimer Disease

(2010) Angelo Demuro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transmembrane Structures for Alzheimer’s Aβ1−42Oligomers

(2010) Birgit Strodel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Truncated  -amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

(2010) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pulse EPR Spectroscopy Reveals the Coordination Sphere of Copper(II) Ions in the 1–16 Amyloid-β Peptide: A Key Role of the First Two N-Terminus Residues

(2009) Pierre Dorlet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(II) Binding to Amyloid-β Fibrils of Alzheimer’s Disease Reveals a Picomolar Affinity: Stoichiometry and Coordination Geometry Are Independent of Aβ Oligomeric Form

(2009) Claire J. Sarell et al.   BIOCHEMISTRY

Covalently bound fluorescent probes as reporters for hydroxyl radical penetration into liposomal membranes

(2009) Chanel A. Fortier et al.   FREE RADICAL BIOLOGY AND MEDICINE

Efficiency of Histidine-Associating Compounds for Blocking the Alzheimer's Aβ Channel Activity and Cytotoxicity

(2008) Nelson Arispe et al.   BIOPHYSICAL JOURNAL

Bioinorganic chemistry of copper and zinc ions coordinated to amyloid-β peptide

(2008) Peter Faller et al.   DALTON TRANSACTIONS

Determining radical penetration of lipid bilayers with new lipophilic spin traps

(2008) Ayelet Gamliel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Binding of zinc(II) and copper(II) to the full-length Alzheimer’s amyloid-β peptide

(2007) Vello Tõugu et al.   JOURNAL OF NEUROCHEMISTRY