N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

Stabilization of Brain Mast Cells Alleviates LPS-Induced Neuroinflammation by Inhibiting Microglia Activation

(2019) Hongquan Dong et al.   Frontiers in Cellular Neuroscience

Blood-Brain Barrier Dysfunction in Ischemic Stroke: Targeting Tight Junctions and Transporters for Vascular Protection

(2018) Wazir Abdullahi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines

(2018) Solmaz Nasseri Maleki et al.   JOURNAL OF CHEMICAL NEUROANATOMY

2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease

(2018) Marika Cordaro et al.   MOLECULAR NEUROBIOLOGY

The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) in Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats

(2018) Rosanna Di Paola et al.   Frontiers in Pharmacology

Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis

(2018) Roberta Fusco et al.   Oncotarget

Brain SIRT1 Mediates Metabolic Homeostasis and Neuroprotection

(2018) Jing Xu et al.   Frontiers in Endocrinology

Genipin protects against cerebral ischemia-reperfusion injury by regulating the UCP2-SIRT3 signaling pathway

(2018) Busi Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Cerebral ischemic damage in diabetes: an inflammatory perspective

(2017) Vibha Shukla et al.   Journal of Neuroinflammation

N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury

(2017) Daniela Impellizzeri et al.   JOURNAL OF NEUROTRAUMA

Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects

(2017) Susana Cardoso et al.   NEUROTOXICITY RESEARCH

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

(2017) Mootaz M. Salman et al.   Frontiers in Cellular Neuroscience

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

(2017) Stefania Petrosino et al.   Frontiers in Pharmacology

Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis

(2016) Marco Migliore et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evidence of CCR2-independent transmigration of Ly6C hi monocytes into the brain after permanent cerebral ischemia in mice

(2016) Hannah X. Chu et al.   BRAIN RESEARCH

The antioxidant uncoupling protein 2 stimulates hnRNPA2/B1, GLUT1 and PKM2 expression and sensitizes pancreas cancer cells to glycolysis inhibition

(2016) Jessica Brandi et al.   FREE RADICAL BIOLOGY AND MEDICINE

2-pentadecyl-2-oxazoline: Identification in coffee, synthesis and activity in a rat model of carrageenan-induced hindpaw inflammation

(2016) Daniela Impellizzeri et al.   PHARMACOLOGICAL RESEARCH

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation

(2015) Alison Ribeiro et al.   ACS Chemical Biology

Synthesis and Evaluation of 3-(furo[2,3-b]pyridin-3-yl)-4-(1H-indol-3-yl)-maleimides as Novel GSK-3βInhibitors and Anti-Ischemic Agents

(2015) Qing Ye et al.   Chemical Biology & Drug Design

Inflammatory Responses in Brain Ischemia

(2015) Masahito Kawabori et al.   CURRENT MEDICINAL CHEMISTRY

Immunohistochemical Analysis of Paraoxonases and Chemokines in Arteries of Patients with Peripheral Artery Disease

(2015) Anna Hernández-Aguilera et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MCP-induced protein 1 mediates the minocycline-induced neuroprotection against cerebral ischemia/reperfusion injury in vitro and in vivo

(2015) Zhuqing Jin et al.   Journal of Neuroinflammation

N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution

(2015) Stephen D. Skaper et al.   MOLECULAR NEUROBIOLOGY

Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

(2015) Stefania Petrosino et al.   PHARMACOLOGICAL RESEARCH

Neuroprotective effect and underlying mechanism of sodium danshensu [3-(3,4-dihydroxyphenyl) lactic acid from Radix and Rhizoma Salviae miltiorrhizae = Danshen] against cerebral ischemia and reperfusion injury in rats

(2015) Chao Guo et al.   PHYTOMEDICINE

Potential analgesic effects of a novel N-acylethanolamine acid amidase inhibitor F96 through PPAR-α

(2015) Longhe Yang et al.   Scientific Reports

Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man

(2015) Carlo Caltagirone et al.   Translational Stroke Research

Effects of Etanercept against Transient Cerebral Ischemia in Diabetic Rats

(2015) Naohiro Iwata et al.   Biomed Research International

Blood-brain barrier dysfunction in disorders of the developing brain

(2015) Raffaella Moretti et al.   Frontiers in Neuroscience

Neuroprotective Properties of Peroxisome Proliferator-Activated Receptor Alpha (PPARα) and its Lipid Ligands

(2014) Marco Fidaleo et al.   CURRENT MEDICINAL CHEMISTRY

Harnessing the anti-inflammatory potential of palmitoylethanolamide

(2014) Mireille Alhouayek et al.   DRUG DISCOVERY TODAY

Molecular Regulation of Cell Fate in Cerebral Ischemia: Role of the Inflammasome and Connected Pathways

(2014) George Trendelenburg   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Propofol Reduces Inflammatory Reaction and Ischemic Brain Damage in Cerebral Ischemia in Rats

(2014) Song-sheng Shi et al.   NEUROCHEMICAL RESEARCH

Advances in the discovery of N-acylethanolamine acid amidase inhibitors

(2014) Tiziano Bandiera et al.   PHARMACOLOGICAL RESEARCH

Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury

(2014) Emanuela Esposito et al.   PHARMACOLOGICAL RESEARCH

Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)

(2014) Daniela Impellizzeri et al.   PHARMACOLOGICAL RESEARCH

Mast cells, glia and neuroinflammation: partners in crime?

(2013) Stephen D. Skaper et al.   IMMUNOLOGY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Mast cells on the mind: new insights and opportunities

(2013) Rae Silver et al.   TRENDS IN NEUROSCIENCES

Causes of vision loss worldwide, 1990–2010: a systematic analysis

(2013) Rupert R A Bourne et al.   Lancet Global Health

Endogenous Molecules Stimulating N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA)

(2012) Tatsuya Tai et al.   ACS Chemical Neuroscience

Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase

(2012) Yumiko Yamano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats

(2012) Akbar Ahmad et al.   BRAIN RESEARCH

Mast cell-glia axis in neuroinflammation and therapeutic potential of the anandamide congener palmitoylethanolamide

(2012) S. D. Skaper et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Time Course, Distribution and Cell Types of Induction of Transforming Growth Factor Betas following Middle Cerebral Artery Occlusion in the Rat Brain

(2012) Gabriella Pál et al.   PLoS One

Allocation techniques for balance at baseline in cluster randomized trials: a methodological review

(2012) Noah M Ivers et al.   Trials

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Tissue distribution and expression of paraoxonases and chemokines in mouse: the ubiquitous and joint localisation suggest a systemic and coordinated role

(2010) Fernando Rodríguez-Sanabria et al.   JOURNAL OF MOLECULAR HISTOLOGY

Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies

(2010) The Emerging Risk Factors Collaboration   LANCET

Protective effect of albumin on VEGF and brain edema in acute ischemia in rats

(2010) Xiaomei Yao et al.   NEUROSCIENCE LETTERS

N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA)

(2010) Natsuo Ueda et al.   PROGRESS IN LIPID RESEARCH

Neuroprotective effect of 5,7,3′,4′,5′-pentahydroxy dihdroflavanol-3-O-(2″-O-galloyl)-β-d-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat

(2009) Rathinam ArunaDevi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Data presentation in rodent stroke studies and the predictive value of confidence intervals

(2009) Michael E. Sughrue et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1–uncoupling protein 2 pathway

(2009) D. Della-Morte et al.   NEUROSCIENCE

Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat

(2009) Rathinam ArunaDevi et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

(2009) C. Solorzano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mast Cells Are Early Responders After Hypoxia-Ischemia in Immature Rat Brain

(2009) Yuxuan Jin et al.   STROKE

Endocannabinoids mediate neuroprotection after transient focal cerebral ischemia

(2008) Markus Schomacher et al.   BRAIN RESEARCH

Research Into Neuroprotection Must Continue … but With a Different Approach

(2008) Muhammad S. Hussain et al.   STROKE