Consistent Biomarkers and Related Pathogenesis Underlying Asthma Revealed by Systems Biology Approach

Biomarker Discovery for Immunotherapy of Pituitary Adenomas: Enhanced Robustness and Prediction Ability by Modern Computational Tools

(2019) Qingxia Yang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pathway enrichment analysis and visualization of omics data using g:Profiler, GSEA, Cytoscape and EnrichmentMap

(2019) Jüri Reimand et al.   Nature Protocols

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

(2019) Guangyan Zhou et al.   NUCLEIC ACIDS RESEARCH

Epigenomics and Transcriptomics in the Prediction and Diagnosis of Childhood Asthma: Are We There Yet?

(2019) Erick Forno et al.   Frontiers in Pediatrics

Prevalence, risk factors, and management of asthma in China: a national cross-sectional study

(2019) Kewu Huang et al.   LANCET

Higher mortality of adults with asthma: A 15-year follow-up of a population-based cohort

(2018) R. E. Lemmetyinen et al.   ALLERGY

Dissecting Asthma Transcriptomics: Does Site Matter?

(2018) Emma de Jong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma

(2018) Akul Singhania et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Phosphorylation of low density lipoprotein receptor-related protein 6 is involved in receptor for advanced glycation end product-mediated β-catenin stabilization in a toluene diisocyanate-induced asthma model

(2018) Jing Xiong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Integrative omics for health and disease

(2018) Konrad J. Karczewski et al.   NATURE REVIEWS GENETICS

The Genetics and Genomics of Asthma

(2018) Saffron A.G. Willis-Owen et al.   Annual Review of Genomics and Human Genetics

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

(2018) Nick Shrine et al.   Lancet Respiratory Medicine

Runx2, a novel regulator for goblet cell differentiation and asthma development

(2017) Ning Shi et al.   FASEB JOURNAL

IL-1β upregulates Muc5ac expression via NF-κB-induced HIF-1α in asthma

(2017) Shouzhen Wu et al.   IMMUNOLOGY LETTERS

Asthma status is associated with decreased risk of aggressive urothelial bladder cancer

(2017) Marta Rava et al.   INTERNATIONAL JOURNAL OF CANCER

Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

(2017) Gang Liu et al.   JOURNAL OF PATHOLOGY

Identification of potential transcriptomic markers in developing asthma: An integrative analysis of gene expression profiles

(2017) Fang Fang et al.   MOLECULAR IMMUNOLOGY

A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing

(2017) Ian Todd et al.   PHARMACOLOGICAL RESEARCH

Plasma proteins as potential targets of abnormal Savda syndrome in asthma patients treated with unique Uighur prescription

(2017) Canhua Zhang et al.   Experimental and Therapeutic Medicine

Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma

(2017) Akul Singhania et al.   PLoS One

ggtree: anrpackage for visualization and annotation of phylogenetic trees with their covariates and other associated data

(2016) Guangchuang Yu et al.   Methods in Ecology and Evolution

Asthma–COPD Overlap. Clinical Relevance of Genomic Signatures of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease

(2015) Stephanie A. Christenson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PharmacoGx: an R package for analysis of large pharmacogenomic datasets

(2015) Petr Smirnov et al.   BIOINFORMATICS

GOplot: an R package for visually combining expression data with functional analysis: Fig. 1.

(2015) Wencke Walter et al.   BIOINFORMATICS

Orchestrating high-throughput genomic analysis with Bioconductor

(2015) Wolfgang Huber et al.   NATURE METHODS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Epigenetics and autoimmune diseases: the X chromosome-nucleolus nexus

(2015) Wesley H. Brooks et al.   Frontiers in Genetics

Gene Expression in Relation to Exhaled Nitric Oxide Identifies Novel Asthma Phenotypes with Unique Biomolecular Pathways

(2014) Brian D. Modena et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A comparative analysis of computational approaches and algorithms for protein subcomplex identification

(2014) Nazar Zaki et al.   Scientific Reports

Role of interleukin 33 in respiratory allergy and asthma

(2014) Heidi Makrinioti et al.   Lancet Respiratory Medicine

The Impact of Allergic Rhinitis and Asthma on Human Nasal and Bronchial Epithelial Gene Expression

(2013) Ariane H. Wagener et al.   PLoS One

Untangling asthma phenotypes and endotypes

(2012) I. Agache et al.   ALLERGY

Hypoxia Response in Asthma

(2012) Tanveer Ahmad et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction

(2012) Bradley W. Schroeder et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

(2012) John J. O'Shea et al.   IMMUNITY

MicroRNA-181a, -146a and -146b in spleen CD4+ T lymphocytes play proinflammatory roles in a murine model of asthma

(2012) Meng-Jie Feng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

Reuse of public genome-wide gene expression data

(2012) Johan Rung et al.   NATURE REVIEWS GENETICS

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

(2011) Manuel AR Ferreira et al.   LANCET

Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer

(2011) W Bu et al.   ONCOGENE

Decreased Fibronectin Production Significantly Contributes to Dysregulated Repair of Asthmatic Epithelium

(2010) Anthony Kicic et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Metabolic Abnormalities in Children with Asthma

(2010) Lesley Cottrell et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mechanical Stretch Up-regulates MicroRNA-26a and Induces Human Airway Smooth Muscle Hypertrophy by Suppressing Glycogen Synthase Kinase-3β

(2010) Junaith S. Mohamed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+ homeostasis and structural and functional remodelling of airway smooth muscle in asthma

(2010) K. Mahn et al.   THORAX

Seretide: a pharmacoeconomic analysis

(2010) Leandro Fritscher et al.   JOURNAL OF MEDICAL ECONOMICS

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Novel and recurrent keratin 6A (KRT6A) mutations in Chinese patients with pachyonychia congenita type 1

(2009) Y.M. Lv et al.   BRITISH JOURNAL OF DERMATOLOGY

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

(2009) Gilles Thomas et al.   NATURE GENETICS

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Effect of boldo (Peumus boldusMolina) infusion on lipoperoxidation induced by cisplatin in mice liver

(2009) J. Fernández et al.   PHYTOTHERAPY RESEARCH

arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

(2008) Audrey Kauffmann et al.   BIOINFORMATICS

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS