Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c

MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2

(2017) Richard Y. Kim et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The inhibitor of semicarbazide-sensitive amine oxidase, PXS-4728A, ameliorates key features of chronic obstructive pulmonary disease in a mouse model

(2016) A G Jarnicki et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting PI3K-p110α Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

(2015) Alan Chen-Yu Hsu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Alteration of Airway Reactivity and Reduction of Ryanodine Receptor Expression by Cigarette Smoke in Mice

(2015) Chantal Donovan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease

(2015) T J Haw et al.   Mucosal Immunology

Integrin α11β1 regulates cancer stromal stiffness and promotes tumorigenicity and metastasis in non-small cell lung cancer

(2015) R Navab et al.   ONCOGENE

Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma

(2015) Ama-Tawiah Essilfie et al.   THORAX

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity

(2015) Christopher M. Evans et al.   Nature Communications

Fibulin1C peptide induces cell attachment and extracellular matrix deposition in lung fibroblasts

(2015) Qi Ge et al.   Scientific Reports

Periostin is required for maximal airways inflammation and hyperresponsiveness in mice

(2014) J. Kelley Bentley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Importance of Mast Cell Prss31/Transmembrane Tryptase/Tryptase-γ in Lung Function and Experimental Chronic Obstructive Pulmonary Disease and Colitis

(2014) Philip M. Hansbro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL1 Inhibits Airway Smooth Muscle Cell Migration through the Decoy Receptor Duffy Antigen Receptor for Chemokines

(2014) L. A. Al-Alwan et al.   JOURNAL OF IMMUNOLOGY

Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis

(2014) Q Wang et al.   ONCOGENE

Novel Small Airway Bronchodilator Responses to Rosiglitazone in Mouse Lung Slices

(2013) Jane E. Bourke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

CXCL1 is a negative regulator of mast cell chemotaxis to airway smooth muscle cell productsin vitro

(2013) H. Alkhouri et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Airway epithelial regulation of pulmonary immune homeostasis and inflammation

(2013) Teal S. Hallstrand et al.   CLINICAL IMMUNOLOGY

Murine models of infectious exacerbations of airway inflammation

(2013) Malcolm Ronald Starkey et al.   CURRENT OPINION IN PHARMACOLOGY

Bradykinin-induced asthmatic fibroblast/myofibroblast activities via bradykinin B2 receptor and different MAPK pathways

(2013) Federica Sabatini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma

(2013) Sejal Saglani et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease

(2013) M R Starkey et al.   Mucosal Immunology

Generation of a human airway epithelium derived basal cell line with multipotent differentiation capacity

(2013) Matthew S Walters et al.   RESPIRATORY RESEARCH

Untangling asthma phenotypes and endotypes

(2012) I. Agache et al.   ALLERGY

Th2 cytokine antagonists: potential treatments for severe asthma

(2012) Philip M Hansbro et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients

(2012) Guiquan Jia et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Components of Streptococcus pneumoniae Suppress Allergic Airways Disease and NKT Cells by Inducing Regulatory T Cells

(2012) A. N. Thorburn et al.   JOURNAL OF IMMUNOLOGY

Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease

(2012) M R Starkey et al.   Mucosal Immunology

Chlamydia muridarum Lung Infection in Infants Alters Hematopoietic Cells to Promote Allergic Airway Disease in Mice

(2012) Malcolm R. Starkey et al.   PLoS One

CombinedHaemophilus influenzaerespiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma

(2012) Ama-Tawiah Essilfie et al.   THORAX

Cytokine/anti-cytokine therapy - novel treatments for asthma?

(2011) Philip M Hansbro et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche

(2011) Hironobu Fujiwara et al.   CELL

Bronchial epithelial cells release IL-6, CXCL1 and CXCL8 upon mast cell interaction

(2011) Ju Cao et al.   CYTOKINE

Tenascin-C deficiency attenuates TGF-β-mediated fibrosis following murine lung injury

(2010) William A. Carey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells

(2010) J. A. Preston et al.   EUROPEAN RESPIRATORY JOURNAL

Chlamydial Respiratory Infection during Allergen Sensitization Drives Neutrophilic Allergic Airways Disease

(2010) J. C. Horvat et al.   JOURNAL OF IMMUNOLOGY

Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?

(2010) Justine Y. Lau et al.   PLoS One

Roles of epithelial cell-derived periostin in TGF-  activation, collagen production, and collagen gel elasticity in asthma

(2010) S. S. Sidhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease

(2010) A. N. Thorburn et al.   THORAX

The outer wall of small airways is a major site of remodeling in fatal asthma

(2009) Marisa Dolhnikoff et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation

(2009) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

Asthma

(2009) Christopher H. Fanta   NEW ENGLAND JOURNAL OF MEDICINE

Tenascins and their implications in diseases and tissue mechanics

(2009) F. Brellier et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling

(2008) Ramzi Fattouh et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Allergy and the lung

(2008) G. Passalacqua et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY