Promising Cytomegalovirus-Based Vaccine Vector Induces Robust CD8+ T-Cell Response

Estimation of the worldwide seroprevalence of cytomegalovirus: A systematic review and meta-analysis

(2019) Mohamed Zuhair et al.   REVIEWS IN MEDICAL VIROLOGY

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

(2019) Scott G. Hansen et al.   PLoS One

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

(2018) Scott G Hansen et al.   NATURE MEDICINE

The Human Cytomegalovirus, from Oncomodulation to Oncogenesis

(2018) Georges Herbein   Viruses-Basel

Human cytomegalovirus-vectored vaccines against HIV

(2018) Maria Abad-Fernandez et al.   Current Opinion in HIV and AIDS

Current views on the potential for development of a HIV vaccine

(2017) Kristen W. Cohen et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Fibroblast-adapted human CMV vaccines elicit predominantly conventional CD8 T cell responses in humans

(2017) Susan E. Murray et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Impact of Antibodies and Strain Polymorphisms on Cytomegalovirus Entry and Spread in Fibroblasts and Epithelial Cells

(2017) Xiaohong Cui et al.   JOURNAL OF VIROLOGY

Intratumoral infection by CMV may change the tumor environment by directly interacting with tumor-associated macrophages to promote cancer immunity

(2017) Dan A. Erkes et al.   Human Vaccines & Immunotherapeutics

Progress in HIV vaccine development

(2017) Denise C. Hsu et al.   Human Vaccines & Immunotherapeutics

Phase 1 Clinical Trial of a Replication-Defective Human Cytomegalovirus (CMV) Vaccine

(2017) Stuart Adler et al.   Open Forum Infectious Diseases

Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice

(2017) Lindsey B. Crawford et al.   Scientific Reports

Antiviral CD8 + T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion

(2016) Srinika Ranasinghe et al.   IMMUNITY

The comings and goings of MHC class I molecules herald a new dawn in cross-presentation

(2016) J. Magarian Blander   IMMUNOLOGICAL REVIEWS

Cytomegalovirus and immunotherapy: opportunistic pathogen, novel target for cancer and a promising vaccine vector

(2016) Michael Quinn et al.   Immunotherapy

Distinct Roles for Human Cytomegalovirus Immediate Early Proteins IE1 and IE2 in the Transcriptional Regulation of MICA and PVR/CD155 Expression

(2016) Benedetta Pignoloni et al.   JOURNAL OF IMMUNOLOGY

A Phase 1 Study of 4 Live, Recombinant Human Cytomegalovirus Towne/Toledo Chimera Vaccines in Cytomegalovirus–Seronegative Men

(2016) Stuart P. Adler et al.   JOURNAL OF INFECTIOUS DISEASES

Functional analysis of human cytomegalovirus UL/b′ region using SCID-hu mouse model

(2016) Kalpana Dulal et al.   JOURNAL OF MEDICAL VIROLOGY

Repair of a Mutation Disrupting the Guinea Pig Cytomegalovirus Pentameric Complex Acquired during Fibroblast Passage Restores Pathogenesis in Immune-Suppressed Guinea Pigs and in the Context of Congenital Infection

(2016) Michael A. McVoy et al.   JOURNAL OF VIROLOGY

Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung

(2016) K M Morabito et al.   Mucosal Immunology

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

(2016) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Impact of pre-adapted HIV transmission

(2016) Jonathan M Carlson et al.   NATURE MEDICINE

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

A replication-defective human cytomegalovirus vaccine for prevention of congenital infection

(2016) D. Wang et al.   Science Translational Medicine

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

(2016) Iryna Dekhtiarenko et al.   PLoS Pathogens

Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome

(2016) Qianglin Fang et al.   eLife

Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

(2016) Simone A. Joosten et al.   Journal of Immunology Research

Constitutive activation of STAT3 in breast cancer cells: A review

(2015) Kasturi Banerjee et al.   INTERNATIONAL JOURNAL OF CANCER

Soluble Human Cytomegalovirus gH/gL/pUL128–131 Pentameric Complex, but Not gH/gL, Inhibits Viral Entry to Epithelial Cells and Presents Dominant Native Neutralizing Epitopes

(2015) John W. Loughney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic cancer vaccines

(2015) Cornelis J.M. Melief et al.   JOURNAL OF CLINICAL INVESTIGATION

Is CMV a target in pediatric glioblastoma? Expression of CMV proteins, pp65 and IE1-72 and CMV nucleic acids in a cohort of pediatric glioblastoma patients

(2015) Amanda Wakefield et al.   JOURNAL OF NEURO-ONCOLOGY

The balance between protective and pathogenic immune responses in the TB-infected lung

(2015) Ian M Orme et al.   NATURE IMMUNOLOGY

A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose

(2015) Yoshimi Tsuda et al.   VACCINE

Cytomegalovirus-Based Vaccine Expressing a Modified Tumor Antigen Induces Potent Tumor-Specific CD8 + T-cell Response and Protects Mice from Melanoma

(2015) Zhijuan Qiu et al.   Cancer Immunology Research

The Story of Human Cytomegalovirus and Cancer: Increasing Evidence and Open Questions

(2015) Martin Michaelis et al.   NEOPLASIA

Host Evasion and Exploitation Schemes of Mycobacterium tuberculosis

(2014) C.J. Cambier et al.   CELL

A Novel Murine Cytomegalovirus Vaccine Vector Protects againstMycobacterium tuberculosis

(2014) Peter C. L. Beverley et al.   JOURNAL OF IMMUNOLOGY

Tuberculosis Vaccines and Prevention of Infection

(2014) Thomas R. Hawn et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Location, location, location

(2014) John R Webb et al.   OncoImmunology

The Oncogenic Potential of Human Cytomegalovirus and Breast Cancer

(2014) Georges Herbein et al.   Frontiers in Oncology

Cytomegalovirus-based cancer vaccines expressing TRP2 induce rejection of melanoma in mice

(2013) Guangwu Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human Cytomegalovirus Major Immediate Early 1 Protein Targets Host Chromosomes by Docking to the Acidic Pocket on the Nucleosome Surface

(2013) K. Mucke et al.   JOURNAL OF VIROLOGY

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

(2013) Scott M. Hammer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fetal Human Cytomegalovirus Transmission Correlates with Delayed Maternal Antibodies to gH/gL/pUL128-130-131 Complex during Primary Infection

(2013) Daniele Lilleri et al.   PLoS One

Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

(2013) S. G. Hansen et al.   SCIENCE

A Cytomegalovirus-based Vaccine Expressing a Single Tumor-specific CD8+ T-cell Epitope Delays Tumor Growth in a Murine Model of Prostate Cancer

(2012) Elena N. Klyushnenkova et al.   JOURNAL OF IMMUNOTHERAPY

Generation of Polyclonal CMV-specific T Cells for the Adoptive Immunotherapy of Glioblastoma

(2012) Alexia Ghazi et al.   JOURNAL OF IMMUNOTHERAPY

The Human Cytomegalovirus UL51 Protein Is Essential for Viral Genome Cleavage-Packaging and Interacts with the Terminase Subunits pUL56 and pUL89

(2012) Eva Maria Borst et al.   JOURNAL OF VIROLOGY

Impact of Preexisting Adenovirus Vector Immunity on Immunogenicity and Protection Conferred with an Adenovirus-Based H5N1 Influenza Vaccine

(2012) Aseem Pandey et al.   PLoS One

Restoration of viral epithelial tropism improves immunogenicity in rabbits and rhesus macaques for a whole virion vaccine of human cytomegalovirus

(2012) Tong-Ming Fu et al.   VACCINE

Bacterial Artificial Chromosome Clones of Viruses Comprising the Towne Cytomegalovirus Vaccine

(2011) Xiaohong Cui et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Role of STAT3 decoy oligodeoxynucleotides on cell invasion and chemosensitivity in human epithelial ovarian cancer cells

(2010) Xiaolei Zhang et al.   CANCER GENETICS AND CYTOGENETICS

Immunoglobulin to zona pellucida 3 mediates ovarian damage and infertility after contraceptive vaccination in mice

(2010) Megan L. Lloyd et al.   JOURNAL OF AUTOIMMUNITY

Preexisting Vaccinia Virus Immunity Decreases SIV-Specific Cellular Immunity but Does Not Diminish Humoral Immunity and Efficacy of a DNA/MVA Vaccine

(2010) S. Kannanganat et al.   JOURNAL OF IMMUNOLOGY

Targeting early infection to prevent HIV-1 mucosal transmission

(2010) Ashley T. Haase   NATURE

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Safety and Immunogenicity of a Replication‐Incompetent Adenovirus Type 5 HIV‐1 Clade Bgag/pol/nefVaccine in Healthy Adults

(2008) Frances H. Priddy et al.   CLINICAL INFECTIOUS DISEASES

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Cytomegalovirus vaccines fail to induce epithelial entry neutralizing antibodies comparable to natural infection

(2008) Xiaohong Cui et al.   VACCINE