Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

(2017) Benjamin Mordmüller et al.   NATURE

Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver

(2017) Sathit Pichyangkul et al.   PLoS One

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

(2017) Kirsten E. Lyke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

(2016) Andrew S Ishizuka et al.   NATURE MEDICINE

Clinical development of RTS,S/AS malaria vaccine: a systematic review of clinical Phase I–III trials

(2015) Selidji T Agnandji et al.   Future Microbiology

Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

(2015) Joao C. Aguiar et al.   PLoS One

Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults

(2015) Caroline Ogwang et al.   Science Translational Medicine

Large screen approaches to identify novel malaria vaccine candidates

(2015) D. Huw Davies et al.   VACCINE

Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals

(2014) Susanne H. Hodgson et al.   JOURNAL OF INFECTIOUS DISEASES

Using infective mosquitoes to challenge monkeys with Plasmodium knowlesi in malaria vaccine studies

(2014) Jittawadee R Murphy et al.   MALARIA JOURNAL

Translating the Immunogenicity of Prime-boost Immunization With ChAd63 and MVA ME-TRAP From Malaria Naive to Malaria-endemic Populations

(2014) Domtila Kimani et al.   MOLECULAR THERAPY

A Phase Ia Study to Assess the Safety and Immunogenicity of New Malaria Vaccine Candidates ChAd63 CS Administered Alone and with MVA CS

(2014) Eoghan de Barra et al.   PLoS One

Sporozoite Immunization of Human Volunteers under Mefloquine Prophylaxis Is Safe, Immunogenic and Protective: A Double-Blind Randomized Controlled Clinical Trial

(2014) Else M. Bijker et al.   PLoS One

Human Infections and Detection of Plasmodium knowlesi

(2013) B. Singh et al.   CLINICAL MICROBIOLOGY REVIEWS

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

DNA Prime/Adenovirus Boost Malaria Vaccine Encoding P. falciparum CSP and AMA1 Induces Sterile Protection Associated with Cell-Mediated Immunity

(2013) Ilin Chuang et al.   PLoS One

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

(2013) R. A. Seder et al.   SCIENCE

Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

(2013) S. G. Hansen et al.   SCIENCE

Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation

(2013) Katie J. Ewer et al.   Nature Communications

Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection

(2012) Vittoria Offeddu et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Hidden Memories: Frontline Memory T Cells and Early Pathogen Interception

(2012) D. Masopust et al.   JOURNAL OF IMMUNOLOGY

Reevaluation of the Coding Potential and Proteomic Analysis of the BAC-Derived Rhesus Cytomegalovirus Strain 68-1

(2012) D. Malouli et al.   JOURNAL OF VIROLOGY

ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans

(2012) Susanne H Sheehy et al.   MOLECULAR THERAPY

Protective CD8+ T lymphocytes in Primates Immunized with Malaria Sporozoites

(2012) Walter R. Weiss et al.   PLoS One

Cutting Edge: Attrition of Plasmodium -Specific Memory CD8 T Cells Results in Decreased Protection That Is Rescued by Booster Immunization

(2011) Nathan W. Schmidt et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus-Specific T Cell Immunity Is Maintained in Immunosenescent Rhesus Macaques

(2011) L. Cicin-Sain et al.   JOURNAL OF IMMUNOLOGY

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Vaccines against malaria

(2011) A. V. S. Hill   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8+ T Cell Immunity

(2011) J. E. Epstein et al.   SCIENCE

Longevity and Composition of Cellular Immune Responses Following Experimental Plasmodium falciparum Malaria Infection in Humans

(2011) Anne C. Teirlinck et al.   PLoS Pathogens

Malaria Vaccine Design: Immunological Considerations

(2010) Michael F. Good et al.   IMMUNITY

Evasion of CD8+ T Cells Is Critical for Superinfection by Cytomegalovirus

(2010) S. G. Hansen et al.   SCIENCE

The Potential Role of Vaccines in the Elimination of Falciparum Malaria and the Eventual Eradication of Malaria

(2009) Christopher V. Plowe et al.   JOURNAL OF INFECTIOUS DISEASES

Immunological mechanisms underlying protection mediated by RTS,S: a review of the available data

(2009) Vasee S Moorthy et al.   MALARIA JOURNAL

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sterile Protection against Plasmodium knowlesi in Rhesus Monkeys from a Malaria Vaccine: Comparison of Heterologous Prime Boost Strategies

(2009) George Jiang et al.   PLoS One

Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria

(2008) N. W. Schmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA