Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans

(2016) Stephanie Fresnay et al.   Journal of Translational Medicine

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

A Conserved HIV-1-Derived Peptide Presented by HLA-E Renders Infected T-cells Highly Susceptible to Attack by NKG2A/CD94-Bearing Natural Killer Cells

(2016) Zachary B. Davis et al.   PLoS Pathogens

Modulation of Host Autophagy during Bacterial Infection: Sabotaging Host Munitions for Pathogen Nutrition

(2016) Pedro Escoll et al.   Frontiers in Immunology

The Dendritic Cell Synapse: A Life Dedicated to T Cell Activation

(2016) Federica Benvenuti   Frontiers in Immunology

Polymorphisms within the human leucocyte antigen-E gene and their associations with susceptibility to rheumatoid arthritis as well as clinical outcome of anti-tumour necrosis factor therapy

(2015) M. Iwaszko et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

(2015) Nadia Caccamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The diversity of the HLA-E-restricted peptide repertoire explains the immunological impact of the Arg107Gly mismatch

(2015) Alexander A. Celik et al.   IMMUNOGENETICS

The burgeoning family of unconventional T cells

(2015) Dale I Godfrey et al.   NATURE IMMUNOLOGY

The Presence of HLA-E-Restricted, CMV-Specific CD8+ T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

(2015) Lucy C. Sullivan et al.   PLoS One

The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma

(2015) Mehrdad Talebian Yazdi et al.   Oncotarget

Human CD8+ T-cells Recognizing Peptides from Mycobacterium tuberculosis (Mtb) Presented by HLA-E Have an Unorthodox Th2-like, Multifunctional, Mtb Inhibitory Phenotype and Represent a Novel Human T-cell Subset

(2015) Krista E. van Meijgaarden et al.   PLoS Pathogens

HLA-E: Presentation of a Broader Peptide Repertoire Impacts the Cellular Immune Response—Implications on HSCT Outcome

(2015) Thomas Kraemer et al.   Stem Cells International

CD8+ T-Cells as Immune Regulators of Multiple Sclerosis

(2015) Sushmita Sinha et al.   Frontiers in Immunology

HLA-E: A Novel Player for Histocompatibility

(2014) Thomas Kraemer et al.   Journal of Immunology Research

Visualizing how T cells collect activation signals in vivo

(2013) Hélène D Moreau et al.   CURRENT OPINION IN IMMUNOLOGY

Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells

(2013) Jianmei W. Leavenworth et al.   JOURNAL OF CLINICAL INVESTIGATION

HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients

(2013) Kim Pannemans et al.   Multiple Sclerosis Journal

CD8+ T Cells Are Required For Glatiramer Acetate Therapy in Autoimmune Demyelinating Disease

(2013) Andrew F. Tyler et al.   PLoS One

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

(2012) Margit H. Lampen et al.   MOLECULAR IMMUNOLOGY

Epstein-Barr virus Peptide Presented by HLA-E is Predominantly Recognized by CD8bright Cells in multiple Sclerosis Patients

(2012) Pernille B. Jørgensen et al.   PLoS One

HLA-E-Restricted Cross-Recognition of Allogeneic Endothelial Cells by CMV-Associated CD8 T Cells: A Potential Risk Factor following Transplantation

(2012) Mathilde Allard et al.   PLoS One

Ex Vivo Kinetics of Early and Long-Term Multifunctional Human Leukocyte Antigen E-Specific CD8+ Cells in Volunteers Immunized with the Ty21a Typhoid Vaccine

(2010) R. Salerno-Goncalves et al.   Clinical and Vaccine Immunology

HLA-E–restricted regulatory CD8+ T cells are involved in development and control of human autoimmune type 1 diabetes

(2010) Hong Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress

(2010) Thorbald van Hall et al.   MICROBES AND INFECTION

Mycobacterium tuberculosis Peptides Presented by HLA-E Molecules Are Targets for Human CD8+ T-Cells with Cytotoxic as well as Regulatory Activity

(2010) Simone A. Joosten et al.   PLoS Pathogens

The nonpolymorphic MHC Qa-1bmediates CD8+T cell surveillance of antigen-processing defects

(2009) Cláudia C. Oliveira et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The HLA‐ER/HLA‐ERGenotype Affects the Natural Course of Hepatitis C Virus (HCV) Infection and Is Associated with HLA‐E–Restricted Recognition of an HCV‐Derived Peptide by Interferon‐γ–Secreting Human CD8+T Cells

(2009) Daniela Schulte et al.   JOURNAL OF INFECTIOUS DISEASES

The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle

(2009) Jeff E. Grotzke et al.   PLoS Pathogens

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies

(2008) Richard Apps et al.   IMMUNOLOGY

Subtle Changes in Peptide Conformation Profoundly Affect Recognition of the Non-Classical MHC Class I Molecule HLA-E by the CD94–NKG2 Natural Killer Cell Receptors

(2008) Hilary L. Hoare et al.   JOURNAL OF MOLECULAR BIOLOGY

The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity

(2008) L. C. Sullivan et al.   TISSUE ANTIGENS