The Role of Exosomal MicroRNAs in the Tumor Microenvironment of Breast Cancer

Exosomes: A Promising Avenue for the Diagnosis of Breast Cancer

(2019) Yiming Meng et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

Exosomal miRNAs from highly metastatic cells can induce metastasis in non-metastatic cells

(2019) Vahid kia et al.   LIFE SCIENCES

Label-free detection of exosomes using a surface plasmon resonance biosensor

(2019) Abu Ali Ibn Sina et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Emerging Function and Clinical Values of Exosomal microRNAs in Cancer

(2019) Man Wang et al.   Molecular Therapy-Nucleic Acids

MiR-130a-3p inhibits migration and invasion by regulating RAB5B in human breast cancer stem cell-like cells

(2018) Xiangjie Kong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A ratiometric electrochemical biosensor for the exosomal microRNAs detection based on bipedal DNA walkers propelled by locked nucleic acid modified toehold mediate strand displacement reaction

(2018) Jing Zhang et al.   BIOSENSORS & BIOELECTRONICS

Circulating microRNAs from the miR-106a–363 cluster on chromosome X as novel diagnostic biomarkers for breast cancer

(2018) Minghui Li et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer-associated fibroblasts in tumor microenvironment – Accomplices in tumor malignancy

(2018) Zehuan Liao et al.   CELLULAR IMMUNOLOGY

Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells

(2018) Wei Yan et al.   NATURE CELL BIOLOGY

Extracellular vesicles in cancer — implications for future improvements in cancer care

(2018) Rong Xu et al.   Nature Reviews Clinical Oncology

Employing mesenchymal stem cells to support tumor-targeted delivery of extracellular vesicle (EV)-encapsulated microRNA-379

(2018) K. P. O’Brien et al.   ONCOGENE

Tumour Heterogeneity of Breast Cancer: From Morphology to Personalised Medicine

(2018) Mohammed A. Aleskandarany et al.   PATHOBIOLOGY

Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A

(2018) Kyoko Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1

(2018) Yaming Li et al.   Cell Death & Disease

Exosome‑encapsulated microRNA‑223‑3p as a minimally invasive biomarker for the early detection of invasive breast cancer

(2018) Mio Yoshikawa et al.   Oncology Letters

Mining of potential microRNAs with clinical correlation - regulation of syndecan-1 expression by miR-122-5p altered mobility of breast cancer cells and possible correlation with liver injury

(2018) YihHuei Uen et al.   Oncotarget

Exosome-mediated breast cancer chemoresistance via miR-155 transfer

(2018) Juliana Carvalho Santos et al.   Scientific Reports

Analysis of MicroRNA Signature Differentially Expressed in Exosomes from Adriamycin-resistant and Parental Human Breast Cancer Cells

(2018) Wei-xian Chen et al.   BIOSCIENCE REPORTS

Malignant canine mammary epithelial cells shed exosomes containing differentially expressed microRNA that regulate oncogenic networks

(2018) Eric J. Fish et al.   BMC CANCER

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

(2018) Ines Stevic et al.   BMC Medicine

D Rhamnose β‑Hederin against human breast cancer by reducing tumor‑derived exosomes

(2018) Wei‑Xian Chen et al.   Oncology Letters

Different signatures of miR-16, miR-30b and miR-93 in exosomes from breast cancer and DCIS patients

(2018) Qingtao Ni et al.   Scientific Reports

In Situ Detection of Plasma Exosomal MicroRNA-1246 for Breast Cancer Diagnostics by a Au Nanoflare Probe

(2018) Ling-Yan Zhai et al.   ACS Applied Materials & Interfaces

Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo

(2018) Zahra Naseri et al.   International Journal of Nanomedicine

Evaluation of exosomal miR-9 and miR-155 targeting PTEN and DUSP14 in highly metastatic breast cancer and their effect on low metastatic cells

(2018) Vahid kia et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

microRNA modified tumor-derived exosomes as novel tools for maturation of dendritic cells

(2018) Adeleh Taghikhani et al.   JOURNAL OF CELLULAR PHYSIOLOGY

EVmiRNA: a database of miRNA profiling in extracellular vesicles

(2018) Teng Liu et al.   NUCLEIC ACIDS RESEARCH

The prognostic and therapeutic application of microRNAs in breast cancer: Tissue and circulating microRNAs

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells

(2017) Nikolina Dioufa et al.   Molecular Cancer

Smuggling gold nanoparticles across cell types – A new role for exosomes in gene silencing

(2017) Catarina Roma-Rodrigues et al.   Nanomedicine-Nanotechnology Biology and Medicine

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells

(2017) Katayoon Pakravan et al.   CELLULAR ONCOLOGY

MicroRNA-155, induced by FOXP3 through transcriptional repression of BRCA1, is associated with tumor initiation in human breast cancer

(2017) Song Gao et al.   Oncotarget

Differential expression of exosomal miRNAs between breast cancer patients with and without recurrence

(2017) Aiko Sueta et al.   Oncotarget

Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

(2017) Elvira Donnarumma et al.   Oncotarget

Exosomal MicroRNAs in Breast Cancer towards Diagnostic and Therapeutic Applications

(2017) Lorenzo Sempere et al.   Cancers

Size-Selective Harvesting of Extracellular Vesicles for Strategic Analyses Towards Tumor Diagnoses

(2016) Chihiro Manri et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Human Endometrial Exosomes Contain Hormone-Specific Cargo Modulating Trophoblast Adhesive Capacity: Insights into Endometrial-Embryo Interactions1

(2016) David W. Greening et al.   BIOLOGY OF REPRODUCTION

Simultaneous and multiplexed detection of exosome microRNAs using molecular beacons

(2016) Ji Hye Lee et al.   BIOSENSORS & BIOELECTRONICS

Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow

(2016) Sarah A. Bliss et al.   CANCER RESEARCH

Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication

(2016) Tek N. Lamichhane et al.   Cellular and Molecular Bioengineering

Recent trends in microRNA research into breast cancer with particular focus on the associations between microRNAs and intrinsic subtypes

(2016) Sasagu Kurozumi et al.   JOURNAL OF HUMAN GENETICS

Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes

(2016) Yao Wei et al.   MOLECULES

Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis

(2016) Z Deng et al.   ONCOGENE

Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts

(2016) S Baroni et al.   Cell Death & Disease

miR-182, of the miR-183 cluster family, is packaged in exosomes and is detected in human exosomes from serum, breast cells and prostate cells

(2016) Brittany L. Mihelich et al.   Oncology Letters

MicroRNA expression profiles of drug-resistance breast cancer cells and their exosomes

(2016) Shanliang Zhong et al.   Oncotarget

Visualization of exosome-mediated miR-210 transfer from hypoxic tumor cells

(2016) Kyung Oh Jung et al.   Oncotarget

A direct quantification method for measuring plasma MicroRNAs identified potential biomarkers for detecting metastatic breast cancer

(2016) Qian Zhao et al.   Oncotarget

Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015

(2015) A. S. Coates et al.   ANNALS OF ONCOLOGY

In situ single step detection of exosome microRNA using molecular beacon

(2015) Ji Hye Lee et al.   BIOMATERIALS

Targeting exosomes from preadipocytes inhibits preadipocyte to cancer stem cell signaling in early-stage breast cancer

(2015) Ramkishore Gernapudi et al.   BREAST CANCER RESEARCH AND TREATMENT

Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype

(2015) Sanket H Shah et al.   CANCER BIOLOGY & THERAPY

Tumor microenvironment: Sanctuary of the devil

(2015) Lanlan Hui et al.   CANCER LETTERS

β-Elemene Reverses Chemoresistance of Breast Cancer Cells by Reducing Resistance Transmission via Exosomes

(2015) Jun Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation

(2015) Xiaomei Teng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)

(2015) Bethany N. Hannafon et al.   Molecular Cancer

Breast Cancer-Specific miR Signature Unique to Extracellular Vesicles Includes "microRNA-like" tRNA Fragments

(2015) N. Guzman et al.   MOLECULAR CANCER RESEARCH

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

(2015) Miranda Y. Fong et al.   NATURE CELL BIOLOGY

MicroRNAs as mediators and communicators between cancer cells and the tumor microenvironment

(2015) F J Kohlhapp et al.   ONCOGENE

Role of the Tumor Microenvironment in Breast Cancer

(2015) Savas D. Soysal et al.   PATHOBIOLOGY

Exosomes from adriamycin-resistant breast cancer cells transmit drug resistance partly by delivering miR-222

(2015) Dan-dan Yu et al.   TUMOR BIOLOGY

Exosomes decrease sensitivity of breast cancer cells to adriamycin by delivering microRNAs

(2015) Ling Mao et al.   TUMOR BIOLOGY

DNAzyme-based probe for circulating microRNA detection in peripheral blood

(2015) Aiguo Wu et al.   Drug Design Development and Therapy

miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity

(2015) Keith O’Brien et al.   Oncotarget

Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

(2015) Nicolas Bovy et al.   Oncotarget

Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins, and metabolites

(2015) Krishna C. Vallabhaneni et al.   Oncotarget

Breast Cancer-Derived Extracellular Vesicles: Characterization and Contribution to the Metastatic Phenotype

(2015) Toni M. Green et al.   Biomed Research International

Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth

(2015) Kazuyoshi Shiga et al.   Cancers

Increased serum levels of circulating exosomal microRNA-373 in receptor-negative breast cancer patients

(2015) Corinna Eichelser et al.   Oncotarget

Molecular characterization of exosome-like vesicles from breast cancer cells

(2014) Stefan Kruger et al.   BMC CANCER

Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

(2014) Yifang Wei et al.   BREAST CANCER RESEARCH AND TREATMENT

MicroRNAome genome: A treasure for cancer diagnosis and therapy

(2014) Ioana Berindan-Neagoe et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis

(2014) Weiying Zhou et al.   CANCER CELL

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

microRNAs in the tumor microenvironment: solving the riddle for a better diagnostics

(2014) Kishore B Challagundla et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer

(2014) Ramesh Singh et al.   Molecular Cancer

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNAs as Biomarkers in Pituitary Tumors

(2014) Antonio Di Ieva et al.   NEUROSURGERY

Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

(2014) C E Weber et al.   ONCOGENE

MicroRNA regulons in tumor microenvironment

(2014) H I Suzuki et al.   ONCOGENE

Intercellular communication by exosomes in placenta: A possible role in cell fusion?

(2014) M. Record   PLACENTA

Exosomes Derived from Mesenchymal Stem Cells Suppress Angiogenesis by Down-Regulating VEGF Expression in Breast Cancer Cells

(2014) Jong-Kuen Lee et al.   PLoS One

Exosomes from Drug-Resistant Breast Cancer Cells Transmit Chemoresistance by a Horizontal Transfer of MicroRNAs

(2014) Wei-xian Chen et al.   PLoS One

Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells

(2014) M. Ono et al.   Science Signaling

Exosomes from docetaxel-resistant breast cancer cells alter chemosensitivity by delivering microRNAs

(2014) Wei-xian Chen et al.   TUMOR BIOLOGY

Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

(2013) Ji-Young Jang et al.   BMC CANCER

Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction

(2013) T Nagasaki et al.   BRITISH JOURNAL OF CANCER

Intercellular Communication by Exosome-Derived microRNAs in Cancer

(2013) Bethany Hannafon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis

(2013) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Tumor cell-derived exosomes: A message in a bottle

(2012) Pedram Kharaziha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

(2011) Mei Yang et al.   Molecular Cancer

Detachment of Breast Tumor Cells Induces Rapid Secretion of Exosomes Which Subsequently Mediate Cellular Adhesion and Spreading

(2011) Rainelli B. Koumangoye et al.   PLoS One

The microRNA network and tumor metastasis

(2009) H Zhang et al.   ONCOGENE

Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis

(2008) Sebastián Giulianelli et al.   INTERNATIONAL JOURNAL OF CANCER

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY