Osteopontin mediates an MZF1–TGF-β1-dependent transformation of mesenchymal stem cells into cancer-associated fibroblasts in breast cancer

Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics

(2015) Nancy Dumont et al.   NEOPLASIA

Prognostic values of osteopontin-c, E-cadherin and β-catenin in breast cancer

(2013) Hui Pang et al.   Cancer Epidemiology

Tumor-associated fibroblast-conditioned medium promotes tumor cell proliferation and angiogenesis

(2013) L.N. Xu et al.   GENETICS AND MOLECULAR RESEARCH

Osteopontin Regulates Epithelial Mesenchymal Transition-Associated Growth of Hepatocellular Cancer in a Mouse Xenograft Model

(2012) Syamal D. Bhattacharya et al.   ANNALS OF SURGERY

Overexpression of myeloid zinc finger 1 suppresses matrix metalloproteinase-2 expression and reduces invasiveness of SiHa human cervical cancer cells

(2012) Su-Ju Tsai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Impact of Tumor Microenvironment and Epithelial Phenotypes on Metabolism in Breast Cancer

(2012) H. A. Brauer et al.   CLINICAL CANCER RESEARCH

ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression

(2012) Bo Rafn et al.   MOLECULAR CELL

Mesenchymal stem cells promote growth and angiogenesis of tumors in mice

(2012) W-H Huang et al.   ONCOGENE

Interaction with colon cancer cells hyperactivates TGF-β signaling in cancer-associated fibroblasts

(2012) L J A C Hawinkels et al.   ONCOGENE

Origins of the Tumor Microenvironment: Quantitative Assessment of Adipose-Derived and Bone Marrow–Derived Stroma

(2012) Shannon Kidd et al.   PLoS One

CDK5RAP3 Is a Novel Repressor of p14ARF in Hepatocellular Carcinoma Cells

(2012) Grace Wing-Yan Mak et al.   PLoS One

Functional Screen of Paracrine Signals in Breast Carcinoma Fibroblasts

(2012) Gui Su et al.   PLoS One

Markers for Characterization of Bone Marrow Multipotential Stromal Cells

(2012) Sally A. Boxall et al.   Stem Cells International

Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth

(2011) Michael Quante et al.   CANCER CELL

Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis

(2011) Zhiyong Mi et al.   CARCINOGENESIS

Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

(2011) Moshe Elkabets et al.   JOURNAL OF CLINICAL INVESTIGATION

Hematopoietic Derived Cell Infiltration of the Intestinal Tumor Microenvironment in ApcMin/+ Mice

(2011) Celestia Davis et al.   MICROSCOPY AND MICROANALYSIS

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial-mesenchymal transition-like state in breast cancer cells in vitro

(2010) M.-Q. Gao et al.   JOURNAL OF CELL SCIENCE

Critical role for osteopontin in diabetic nephropathy

(2010) Susanne B. Nicholas et al.   KIDNEY INTERNATIONAL

Myeloid Zinc Finger 1 Induces Migration, Invasion, and In vivo Metastasis through Axl Gene Expression in Solid Cancer

(2010) G. Mudduluru et al.   MOLECULAR CANCER RESEARCH

Aerosol Delivery of Small Hairpin Osteopontin Blocks Pulmonary Metastasis of Breast Cancer in Mice

(2010) Kyeong-Nam Yu et al.   PLoS One

Autocrine TGF-  and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

(2010) Y. Kojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGFβ: a sleeping giant awoken by integrins

(2010) John J. Worthington et al.   TRENDS IN BIOCHEMICAL SCIENCES

Osteopontin Induces Airway Remodeling and Lung Fibroblast Activation in a Murine Model of Asthma

(2009) Martin Kohan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Osteopontin

(2009) Gudrun Szalay et al.   CIRCULATION RESEARCH

Osteopontin promotes fibrosis in dystrophic mouse muscle by modulating immune cell subsets and intramuscular TGF-β

(2009) Sylvia A. Vetrone et al.   JOURNAL OF CLINICAL INVESTIGATION

Osteopontin modulates angiotensin II–induced inflammation, oxidative stress, and fibrosis of the kidney

(2009) Talya Wolak et al.   KIDNEY INTERNATIONAL

Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

(2009) Manav Korpal et al.   NATURE MEDICINE

Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression

(2009) Erika L. Spaeth et al.   PLoS One

Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging

(2009) Hui Wang et al.   STEM CELLS

Transcriptional regulation of theTGF-β1promoter by androgen receptor

(2008) Wei Qi et al.   BIOCHEMICAL JOURNAL

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts

(2008) C. Anderberg et al.   CANCER RESEARCH

Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

(2008) Sandra S. McAllister et al.   CELL

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Osteopontin Expression Is Required for Myofibroblast Differentiation

(2007) Yair Lenga et al.   CIRCULATION RESEARCH