An overview of nanogel-based vaccines

Biosynthesis of β-d-glucan‑gold nanoparticles, cytotoxicity and oxidative stress in mouse splenocytes

(2019) Luis Hernandez-Adame et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Implantable Synthetic Immune Niche for Spatiotemporal Modulation of Tumor-Derived Immunosuppression and Systemic Antitumor Immunity: Postoperative Immunotherapy

(2018) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Multi-Functional Nanogels as Theranostic Platforms: Exploiting Reversible and Nonreversible Linkages for Targeting, Imaging, and Drug Delivery

(2018) Laura Chambre et al.   BIOCONJUGATE CHEMISTRY

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

(2018) Lutz Nuhn et al.   BIOMATERIALS

TPGS-functionalized and ortho ester-crosslinked dextran nanogels for enhanced cytotoxicity on multidrug resistant tumor cells

(2018) Min Sun et al.   CARBOHYDRATE POLYMERS

Alginate-based cancer-associated, stimuli-driven and turn-on theranostic prodrug nanogel for cancer detection and treatment

(2018) Mingliang Pei et al.   CARBOHYDRATE POLYMERS

Research progress of self-assembled nanogel and hybrid hydrogel systems based on pullulan derivatives

(2018) Tao Zhang et al.   DRUG DELIVERY

Gold nanoparticles: Distribution, bioaccumulation and toxicity. In vitro and in vivo studies

(2018) Carlos Lopez-Chaves et al.   Nanomedicine-Nanotechnology Biology and Medicine

A facile method for the controlled polymerization of biocompatible and thermoresponsive oligo(ethylene glycol) methyl ether methacrylate copolymers

(2018) Teresa Alejo et al.   POLYMER JOURNAL

Radiation-induced synthesis of poly(acrylic acid) nanogels

(2018) Malgorzata Matusiak et al.   RADIATION PHYSICS AND CHEMISTRY

Preparation of nanogels by radiation-induced cross-linking of interpolymer complexes of poly (acrylic acid) with poly (vinyl pyrrolidone) in aqueous medium

(2018) Mohammadreza Ghaffarlou et al.   RADIATION PHYSICS AND CHEMISTRY

Opinion: Making Inactivated and Subunit-Based Vaccines Work

(2018) Brendon Y. Chua et al.   VIRAL IMMUNOLOGY

Applications of nanoparticle systems in drug delivery technology

(2018) Syed A.A. Rizvi et al.   SAUDI PHARMACEUTICAL JOURNAL

One-Step Synthesis of Targeted Acid-Labile Polysaccharide Prodrug for Efficiently Intracellular Drug Delivery

(2018) Di Li et al.   ACS Biomaterials-Science & Engineering

One-Step Synthesis of Targeted Acid-Labile Polysaccharide Prodrug for Efficiently Intracellular Drug Delivery

(2018) Di Li et al.   ACS Biomaterials Science & Engineering

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

M cell targeting engineered biomaterials for effective vaccination

(2018) Mohammad Ariful Islam et al.   BIOMATERIALS

pH-sensitive nanogels with ortho ester linkages prepared via thiol-ene click chemistry for efficient intracellular drug release

(2017) Jun Wang et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

On the kinetics of chitosan/tripolyphosphate micro- and nanogel aggregation and their effects on particle polydispersity

(2017) Yan Huang et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Analysis of chitosan/tripolyphosphate micro- and nanogel yields is key to understanding their protein uptake performance

(2017) Yuhang Cai et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

pH-degradable PVA-based nanogels via photo-crosslinking of thermo-preinduced nanoaggregates for controlled drug delivery

(2017) Wei Chen et al.   JOURNAL OF CONTROLLED RELEASE

Thiol-functionalized nanogels as reactive plasticizers for crosslinked polymer networks

(2017) Manju Saraswathy et al.   Journal of the Mechanical Behavior of Biomedical Materials

Self-Assembly of Thermoresponsive Recombinant Silk-Elastinlike Nanogels

(2017) Kyle J. Isaacson et al.   MACROMOLECULAR BIOSCIENCE

Nanogel-based nasal ghrelin vaccine prevents obesity

(2017) T Azegami et al.   Mucosal Immunology

Overcoming multidrug resistance using folate receptor-targeted and pH-responsive polymeric nanogels containing covalently entrapped doxorubicin

(2017) Y. Chen et al.   Nanoscale

Step-by-step build-up of covalent poly(ethylene oxide) nanogel films

(2017) S. Zahouani et al.   Nanoscale

Light-induced release of molecules from polymers

(2017) Pu Xiao et al.   PROGRESS IN POLYMER SCIENCE

Poly-γ-glutamic acid/chitosan nanogel greatly enhances the efficacy and heterosubtypic cross-reactivity of H1N1 pandemic influenza vaccine

(2017) Jihyun Yang et al.   Scientific Reports

UCST-Type Thermosensitive Hairy Nanogels Synthesized by RAFT Polymerization-Induced Self-Assembly

(2017) Wenxin Fu et al.   ACS Macro Letters

Novel poly(vinyl alcohol)-based amphiphilic nanogels by non-covalent boric acid crosslinking of polymeric micelles

(2017) Hen Moshe et al.   Biomaterials Science

Role of omics techniques in the toxicity testing of nanoparticles

(2017) Eleonore Fröhlich   JOURNAL OF NANOBIOTECHNOLOGY

One-Step “Click Chemistry”-Synthesized Cross-Linked Prodrug Nanogel for Highly Selective Intracellular Drug Delivery and Upregulated Antitumor Efficacy

(2016) Yu Zhang et al.   ACS Applied Materials & Interfaces

Self-adjuvanted nanovaccine for cancer immunotherapy: Role of lysosomal rupture-induced ROS in MHC class I antigen presentation

(2016) Ce Wang et al.   BIOMATERIALS

Synthesis and characterization of Schiff base contained dextran microgels in water-in-oil inverse microemulsion

(2016) Hongying Su et al.   CARBOHYDRATE POLYMERS

One-pot syntheses of dual-responsive core cross-linked polymeric micelles and covalently entrapped drug by click chemistry

(2016) Xuan Thang Cao et al.   EUROPEAN POLYMER JOURNAL

An overview on the role of silica-based materials in vaccine development

(2016) Gabriela Navarro-Tovar et al.   Expert Review of Vaccines

Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy

(2016) Zohar Shatsberg et al.   JOURNAL OF CONTROLLED RELEASE

Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation

(2016) Kruti S. Soni et al.   JOURNAL OF CONTROLLED RELEASE

Carbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity

(2016) Reem Alshehri et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Critical Appraisal of RAFT-Mediated Polymerization-Induced Self-Assembly

(2016) Sarah L. Canning et al.   MACROMOLECULES

New progress and prospects: The application of nanogel in drug delivery

(2016) Hui Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

Multi-Functional Nanogels for Tumor Targeting and Redox-Sensitive Drug and siRNA Delivery

(2016) Giorgia Adamo et al.   MOLECULES

Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification

(2016) Nane Vanparijs et al.   Nanomedicine

Strong in vivo antitumor responses induced by an antigen immobilized in nanogels via reducible bonds

(2016) Dandan Li et al.   Nanoscale

Waterborne physically crosslinked antimicrobial nanogels

(2016) Subrata Chattopadhyay et al.   Polymer Chemistry

Cyclo(RGD)-Decorated Reduction-Responsive Nanogels Mediate Targeted Chemotherapy of Integrin Overexpressing Human Glioblastoma In Vivo

(2016) Wei Chen et al.   Small

Time-dependent transition of the immunoglobulin G subclass and immunoglobulin E response in cancer patients vaccinated with cholesteryl pullulan-melanoma antigen gene-A4 nanogel

(2016) Noriaki Kyogoku et al.   Oncology Letters

Self-Assembly Protein Nanogels for Safer Cancer Immunotherapy

(2016) Alberto Purwada et al.   Advanced Healthcare Materials

RAFT-Mediated Polymerization-Induced Self-Assembly of Poly(Acrylic Acid)-b-Poly(Hexafluorobutyl Acrylate): Effect of the pH on the Synthesis of Self-Stabilized Particles

(2016) Jianhua Zhou et al.   Polymers

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

(2015) Atul Srivastava et al.   APMIS

CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses

(2015) Rodney A. Rosalia et al.   BIOMATERIALS

Nanoengineering of vaccines using natural polysaccharides

(2015) Ana Sara Cordeiro et al.   BIOTECHNOLOGY ADVANCES

Nanogels based on alginic aldehyde and gelatin by inverse miniemulsion technique: synthesis and characterization

(2015) P.R. Sarika et al.   CARBOHYDRATE POLYMERS

Controlled/Living Radical Polymerization in Dispersed Systems: An Update

(2015) Per B. Zetterlund et al.   CHEMICAL REVIEWS

Micro- and nanogels with labile crosslinks – from synthesis to biomedical applications

(2015) Xuejiao Zhang et al.   CHEMICAL SOCIETY REVIEWS

Green-step assembly of low density lipoprotein/sodium carboxymethyl cellulose nanogels for facile loading and pH-dependent release of doxorubicin

(2015) Lei He et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Gold nanoparticles and vaccine development

(2015) Jorge Alberto Salazar-González et al.   Expert Review of Vaccines

Anti-cancer vaccination by transdermal delivery of antigen peptide-loaded nanogels via iontophoresis

(2015) Mao Toyoda et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison of Loading Efficiency between Hyperbranched Polymers and Cross-Linked Nanogels at Various Branching Densities

(2015) Robert W. Graff et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques

(2015) Y Fukuyama et al.   Mucosal Immunology

Galactose-functionalized multi-responsive nanogels for hepatoma-targeted drug delivery

(2015) Shaofeng Lou et al.   Nanoscale

Polymerization-Induced Self-Assembly Using Visible Light Mediated Photoinduced Electron Transfer–Reversible Addition–Fragmentation Chain Transfer Polymerization

(2015) Jonathan Yeow et al.   ACS Macro Letters

Nanosurface chemistry and dose govern the bioaccumulation and toxicity of carbon nanotubes, metal nanomaterials and quantum dots in vivo

(2015) Feng Zhao et al.   Science Bulletin

Nanogel-Based Immunologically Stealth Vaccine Targets Macrophages in the Medulla of Lymph Node and Induces Potent Antitumor Immunity

(2014) Daisuke Muraoka et al.   ACS Nano

Surface-Modified P(HEMA-co-MAA) Nanogel Carriers for Oral Vaccine Delivery: Design, Characterization, and In Vitro Targeting Evaluation

(2014) Matilde Durán-Lobato et al.   BIOMACROMOLECULES

Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering

(2014) Yanjiao Jiang et al.   BIOMATERIALS

Liposomes as Nanovaccine Delivery Systems

(2014) Khairunnisa Ghaffar et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Polymerization-Induced Self-Assembly of Block Copolymer Nano-objects via RAFT Aqueous Dispersion Polymerization

(2014) Nicholas J. Warren et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functionalized Polyglycerol Amine Nanogels as Nanocarriers for DNA

(2014) Markus Hellmund et al.   MACROMOLECULAR BIOSCIENCE

Polymer hydrogel functionalized with biodegradable nanoparticles as composite system for controlled drug delivery

(2014) Filippo Rossi et al.   NANOTECHNOLOGY

RAFT (Reversible addition-fragmentation chain transfer) crosslinking (co)polymerization of multi-olefinic monomers to form polymer networks

(2014) Graeme Moad   POLYMER INTERNATIONAL

Facile one-pot synthesis of glucose-sensitive nanogel via thiol-ene click chemistry for self-regulated drug delivery

(2013) Li Zhao et al.   Acta Biomaterialia

Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal Colonization by Streptococcus pneumoniae

(2013) Il Gyu Kong et al.   INFECTION AND IMMUNITY

Characterization of Protein and Peptide Binding to Nanogels Formed by Differently Charged Chitosan Derivatives

(2013) Anastasia Zubareva et al.   MOLECULES

Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells

(2013) Thomas Démoulins et al.   Nanomedicine-Nanotechnology Biology and Medicine

Challenges in Development of Nanoparticle-Based Therapeutics

(2012) Neil Desai   AAPS Journal

Polymer nanogels: A versatile nanoscopic drug delivery platform

(2012) Reuben T. Chacko et al.   ADVANCED DRUG DELIVERY REVIEWS

Biocompatibility of mannan nanogel—safe interaction with plasma proteins

(2012) Sílvia A. Ferreira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis

(2012) Vaia Pliaka et al.   Expert Review of Vaccines

Atom Transfer Radical Polymerization (ATRP): Current Status and Future Perspectives

(2012) Krzysztof Matyjaszewski   MACROMOLECULES

Efficient skin permeation of soluble proteins via flexible and functional nano-carrier

(2011) Won Il Choi et al.   JOURNAL OF CONTROLLED RELEASE

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

(2010) Tomonori Nochi et al.   NATURE MATERIALS

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination of mice with chitosan nanogel-associated recombinant NcPDI against challenge infection with Neospora caninum tachyzoites

(2010) K. DEBACHE et al.   PARASITE IMMUNOLOGY

Synthesis of nanogels/microgels by conventional and controlled radical crosslinking copolymerization

(2010) Nicolas Sanson et al.   Polymer Chemistry

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Photoresponsive Nanogels Based on Photocontrollable Cross-Links

(2009) Jie He et al.   MACROMOLECULES

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

(2009) Andrew B. Lowe   Polymer Chemistry

Humoral immune responses in patients vaccinated with 1–146 HER2 protein complexed with cholesteryl pullulan nanogel

(2008) Shinichi Kageyama et al.   CANCER SCIENCE

Methods for the Preparation and Manufacture of Polymeric Nanoparticles

(2008) Christine Vauthier et al.   PHARMACEUTICAL RESEARCH

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA