Nanogel-based nasal ghrelin vaccine prevents obesity

Safety assessment of FDA-approved (orlistat and lorcaserin) anti-obesity medications

(2015) Bruno Halpern et al.   Expert Opinion On Drug Safety

Nanogel-based pneumococcal surface protein A nasal vaccine induces microRNA-associated Th17 cell responses with neutralizing antibodies against Streptococcus pneumoniae in macaques

(2015) Y Fukuyama et al.   Mucosal Immunology

A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management

(2015) Xavier Pi-Sunyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

The mucosal immune system for vaccine development

(2014) Aayam Lamichhane et al.   VACCINE

Effectiveness of Primary Care–Relevant Treatments for Obesity in Adults: A Systematic Evidence Review for the U.S. Preventive Services Task Force

(2013) Erin S. LeBlanc et al.   ANNALS OF INTERNAL MEDICINE

Immunization Against Active Ghrelin Using Virus-Like Particles for Obesity Treatment

(2013) Sara Andrade et al.   CURRENT PHARMACEUTICAL DESIGN

Nanogel-Based PspA Intranasal Vaccine Prevents Invasive Disease and Nasal Colonization by Streptococcus pneumoniae

(2013) Il Gyu Kong et al.   INFECTION AND IMMUNITY

Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: a pooled analysis of 97 prospective cohorts with 1·8 million participants

(2013)   LANCET

Health and economic burden of the projected obesity trends in the USA and the UK

(2011) Y Claire Wang et al.   LANCET

Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial

(2011) Kishore M Gadde et al.   LANCET

The Peptidic GHS-R antagonist [D-Lys3]GHRP-6 markedly improves adiposity and related metabolic abnormalities in a mouse model of postmenopausal obesity

(2011) L. Maletínská et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Altered metabolic and neurochemical responses to chronic unpredictable stressors in ghrelin receptor-deficient mice

(2010) Z. R. Patterson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Brown fat biology and thermogenesis

(2010) Denis Richard   Frontiers in Bioscience-Landmark

A Novel Intronic Peroxisome Proliferator-activated Receptor γ Enhancer in the Uncoupling Protein (UCP) 3 Gene as a Regulator of Both UCP2 and -3 Expression in Adipocytes

(2010) Anne Bugge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

(2010) Frank L Greenway et al.   LANCET

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

(2010) Tomonori Nochi et al.   NATURE MATERIALS

Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

(2010) Steven R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glucose and Weight Control in Mice with a Designed Ghrelin O-Acyltransferase Inhibitor

(2010) B. P. Barnett et al.   SCIENCE

Orlistat-Associated Adverse Effects and Drug Interactions

(2009) Theodosios D Filippatos et al.   DRUG SAFETY

Ghrelin Induces Abdominal Obesity Via GHS-R-Dependent Lipid Retention

(2009) Jeffrey S. Davies et al.   MOLECULAR ENDOCRINOLOGY

Ghrelin vaccination decreases plasma MCP-1 level in LDLR−/−-mice

(2009) Eija Kellokoski et al.   PEPTIDES

Persistent Diet-Induced Obesity in Male C57BL/6 Mice Resulting from Temporary Obesigenic Diets

(2009) Juen Guo et al.   PLoS One

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure

(2007) Paul T. Pfluger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY