Diagnosis of bacterial sepsis: why are tests for bacteremia not sufficient?

Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease

(2019) Timothy A. Blauwkamp et al.   Nature Microbiology

The Uncertain Clinical Benefit of the T2Bacteria Panel

(2019) David A. Weinrib et al.   ANNALS OF INTERNAL MEDICINE

Diagnosing and Managing Sepsis by Probing the Host Response to Infection: Advances, Opportunities, and Challenges

(2019) Ian L. Gunsolus et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Sepsis Guidelines

(2019) Angela X. Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association Between State-Mandated Protocolized Sepsis Care and In-hospital Mortality Among Adults With Sepsis

(2019) Jeremy M. Kahn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection

(2018) David T. Huang et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiologya

(2018) J Michael Miller et al.   CLINICAL INFECTIOUS DISEASES

Determinants of in-hospital antibiotic prescription behaviour: a systematic review and formation of a comprehensive framework. Category: systematic review

(2018) E.B. Warremana et al.   CLINICAL MICROBIOLOGY AND INFECTION

Association of Adverse Events With Antibiotic Use in Hospitalized Patients

(2017) Pranita D. Tamma et al.   JAMA Internal Medicine

MASTERMIND: Bringing Microbial Diagnostics to the Clinic

(2016) Robin Patel et al.   CLINICAL INFECTIOUS DISEASES

Sepsis: the LightCycler SeptiFast Test MGRADE®, SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi – a systematic review and economic evaluation

(2016) Matt Stevenson et al.   HEALTH TECHNOLOGY ASSESSMENT

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Culture if spikes? Indications and yield of blood cultures in hospitalized medical patients

(2016) Katherine Linsenmeyer et al.   Journal of Hospital Medicine

Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial

(2016) Evelien de Jong et al.   LANCET INFECTIOUS DISEASES

Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

(2016) Timothy E. Sweeney et al.   Science Translational Medicine

A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set

(2015) Timothy E. Sweeney et al.   Science Translational Medicine

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

(2014) Ricard Ferrer et al.   CRITICAL CARE MEDICINE

Abnormal Vital Signs Are Common after Bowel Resection and Do Not Predict Anastomotic Leak

(2014) Larson Erb et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Does This Adult Patient With Suspected Bacteremia Require Blood Cultures?

(2012) Bryan Coburn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department*

(2010) David F. Gaieski et al.   CRITICAL CARE MEDICINE