A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set

A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma

(2014) R. Chen et al.   CANCER RESEARCH

Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour

(2014) Ricard Ferrer et al.   CRITICAL CARE MEDICINE

Gene expression profiling in sepsis: timing, tissue, and translational considerations

(2014) David M. Maslove et al.   TRENDS IN MOLECULAR MEDICINE

Identification of a human neonatal immune-metabolic network associated with bacterial infection

(2014) Claire L. Smith et al.   Nature Communications

Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool

(2013) Raymond K. Auerbach et al.   BIOINFORMATICS

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients

(2013) N. Rapin et al.   BLOOD

An expression atlas of human primary cells: inference of gene function from coexpression networks

(2013) Neil A Mabbott et al.   BMC GENOMICS

Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer

(2013) Ngar-Yee Huen et al.   INTERNATIONAL JOURNAL OF CANCER

Transcriptomic evidence of impaired immunoglobulin G production in fatal septic shock

(2013) Raquel Almansa et al.   JOURNAL OF CRITICAL CARE

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

(2013) Purvesh Khatri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma

(2013) Erin L. Vanzant et al.   Journal of Trauma and Acute Care Surgery

Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans

(2013) Sun Hee Ahn et al.   PLoS One

Mycobacterium abscessus Induces a Limited Pattern of Neutrophil Activation That Promotes Pathogen Survival

(2013) Kenneth C. Malcolm et al.   PLoS One

Transcriptional Instability during Evolving Sepsis May Limit Biomarker Based Risk Stratification

(2013) Antonia Kwan et al.   PLoS One

Hodgkin-Reed-Sternberg Cells in Classical Hodgkin Lymphoma Show Alterations of Genes Encoding the NADPH Oxidase Complex and Impaired Reactive Oxygen Species Synthesis Capacity

(2013) Maciej Giefing et al.   PLoS One

Gene expression profiles in febrile children with defined viral and bacterial infection

(2013) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetics of the Innate Immune Response After Trauma

(2013) Falco Hietbrink et al.   SHOCK

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

(2012) Tamás Dolinay et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

rCUR: an R package for CUR matrix decomposition

(2012) András Bodor et al.   BMC BIOINFORMATICS

Transcript profiling of CD16-positive monocytes reveals a unique molecular fingerprint

(2012) Marion Frankenberger et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Does This Adult Patient With Suspected Bacteremia Require Blood Cultures?

(2012) Bryan Coburn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock

(2012) Eduardo Tamayo et al.   JOURNAL OF CRITICAL CARE

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

(2012) Feng He et al.   Molecular Systems Biology

Expression Profiling of Human Immune Cell Subsets Identifies miRNA-mRNA Regulatory Relationships Correlated with Cell Type Specific Expression

(2012) Florence Allantaz et al.   PLoS One

Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: A pilot study

(2012) I. Martin-Loeches et al.   Medicina Intensiva

Signaling in Innate Immunity and Inflammation

(2012) K. Newton et al.   Cold Spring Harbor Perspectives in Biology

Advances in microfluidic PCR for point-of-care infectious disease diagnostics

(2011) Seungkyung Park et al.   BIOTECHNOLOGY ADVANCES

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

Validation of a gene expression-based subclassification strategy for pediatric septic shock*

(2011) Hector R. Wong et al.   CRITICAL CARE MEDICINE

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

(2011) D. Grimaldi et al.   INTENSIVE CARE MEDICINE

Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma

(2011) Eleni Tsitsiou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza

(2011) Jan-Erik Berdal et al.   JOURNAL OF INFECTION

Aberrant Cell Cycle and Apoptotic Changes Characterise Severe Influenza A Infection – A Meta-Analysis of Genomic Signatures in Circulating Leukocytes

(2011) Grant Parnell et al.   PLoS One

Human transcriptome array for high-throughput clinical studies

(2011) Weihong Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models

(2011) Michael J. Pencina et al.   STATISTICS IN MEDICINE

Dissecting Inflammatory Complications in Critically Injured Patients by Within-Patient Gene Expression Changes: A Longitudinal Clinical Genomics Study

(2011) Keyur H. Desai et al.   PLOS MEDICINE

Interferon-α–Induced TRAIL on Natural Killer Cells Is Associated With Control of Hepatitis C Virus Infection

(2010) Kerstin A. Stegmann et al.   GASTROENTEROLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Review of A Large Clinical Series: Is the Band Count Useful in the Diagnosis of Infection? An Accuracy Study in Critically Ill Patients

(2010) Rodrigo Cavallazzi et al.   JOURNAL OF INTENSIVE CARE MEDICINE

ORIGINAL ARTICLE: The Transcriptome of the Fetal Inflammatory Response Syndrome

(2009) Sally A. Madsen-Bouterse et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia

(2009) D. C. Vinh et al.   BLOOD

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

(2009) Petronela Ancuta et al.   BMC GENOMICS

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum*

(2009) Hector R. Wong et al.   CRITICAL CARE MEDICINE

Gene-expression profiling of peripheral blood mononuclear cells in sepsis*

(2009) Benjamin M. P. Tang et al.   CRITICAL CARE MEDICINE

Chronic Lymphocytic Leukemia and B and T Cells Differ in Their Response to Cyclic Nucleotide Phosphodiesterase Inhibitors

(2009) J. A. Meyers et al.   JOURNAL OF IMMUNOLOGY

Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma

(2009) S Eckerle et al.   LEUKEMIA

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(2009) H Warren et al.   MOLECULAR MEDICINE

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

(2009) Rungnapa Pankla et al.   GENOME BIOLOGY

PASTAA: identifying transcription factors associated with sets of co-regulated genes

(2008) Helge G. Roider et al.   BIOINFORMATICS

Protein-glycan interactions in the control of innate and adaptive immune responses

(2008) Yvette van Kooyk et al.   NATURE IMMUNOLOGY

Validating the genomic signature of pediatric septic shock

(2008) Natalie Cvijanovich et al.   PHYSIOLOGICAL GENOMICS

Plasticity of the Systemic Inflammatory Response to Acute Infection during Critical Illness: Development of the Riboleukogram

(2008) Jonathan E. McDunn et al.   PLoS One

Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure

(2008) Katarina Fredriksson et al.   PLoS One

Effects of 30 min of aerobic exercise on gene expression in human neutrophils

(2007) Shlomit Radom-Aizik et al.   JOURNAL OF APPLIED PHYSIOLOGY