Nuclear envelope deformation controls cell cycle progression in response to mechanical force

Variation in traction forces during cell cycle progression

(2018) Benoit Vianay et al.   BIOLOGY OF THE CELL

Cell adhesion is regulated by CDK1 during the cell cycle

(2018) Matthew C. Jones et al.   JOURNAL OF CELL BIOLOGY

Regulation of cell cycle progression by cell–cell and cell–matrix forces

(2018) Marina Uroz et al.   NATURE CELL BIOLOGY

Emerging views of the nucleus as a cellular mechanosensor

(2018) Tyler J. Kirby et al.   NATURE CELL BIOLOGY

Regulation of genome organization and gene expression by nuclear mechanotransduction

(2017) Caroline Uhler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions

(2017) Heonjong Han et al.   NUCLEIC ACIDS RESEARCH

On the origin of shape fluctuations of the cell nucleus

(2017) Fang-Yi Chu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology

(2017) Jeong-Ki Kim et al.   Nature Communications

The Cell Nucleus Serves as a Mechanotransducer of Tissue Damage-Induced Inflammation

(2016) Balázs Enyedi et al.   CELL

Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha

(2016) Seema S. Desai et al.   HEPATOLOGY

Vascular structural and functional changes: their association with causality in hypertension: models, remodeling and relevance

(2016) Robert MKW Lee et al.   HYPERTENSION RESEARCH

YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing

(2016) Arupratan Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

(2016) Huy Quang Le et al.   NATURE CELL BIOLOGY

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Differential basal-to-apical accessibility of lamin A/C epitopes in the nuclear lamina regulated by changes in cytoskeletal tension

(2015) Teemu O. Ihalainen et al.   NATURE MATERIALS

Mechanical strain induces E-cadherin-dependent Yap1 and  -catenin activation to drive cell cycle entry

(2015) B. W. Benham-Pyle et al.   SCIENCE

ATR Mediates a Checkpoint at the Nuclear Envelope in Response to Mechanical Stress

(2014) Amit Kumar et al.   CELL

Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling

(2014) Veronica A. Codelia et al.   CURRENT BIOLOGY

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

(2011) Leticia Sansores-Garcia et al.   EMBO JOURNAL

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Mitochondrial shape changes: orchestrating cell pathophysiology

(2010) Silvia Campello et al.   EMBO REPORTS

Compression Regulates Mitotic Spindle Length by a Mechanochemical Switch at the Poles

(2009) Sophie Dumont et al.   CURRENT BIOLOGY

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The actin cytoskeleton in spindle assembly and positioning

(2009) Patricia Kunda et al.   TRENDS IN CELL BIOLOGY

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

(2008) José María González et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY