TWEAK promotes hepatic stellate cell migration through activating EGFR/Src and PI3K/AKT pathways

LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway

(2019) Hong Zhang et al.   Cell Death & Disease

miR-224-5p inhibits proliferation, migration, and invasion by targeting PIK3R3/AKT3 in uveal melanoma

(2019) Jianchang Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TRAF4 promotes endometrial cancer cell growth and migration by activation of PI3K/AKT/Oct4 signaling

(2019) Pengmu Xie et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Curcumin protects against hepatic stellate cells activation and migration by inhibiting the CXCL12/CXCR4 biological axis in liver fibrosis：A study in vitro and in vivo

(2018) Lifeng Qin et al.   BIOMEDICINE & PHARMACOTHERAPY

Knockdown of TRIM31 suppresses proliferation and invasion of gallbladder cancer cells by down-regulating MMP2/9 through the PI3K/Akt signaling pathway

(2018) Hui Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Deficiency in augmenter of liver regeneration accelerates liver fibrosis by promoting migration of hepatic stellate cell

(2018) Wei-lun Ai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fn14 deficiency ameliorates psoriasis-like skin disease in a murine model

(2018) L. Peng et al.   Cell Death & Disease

Inhibition of Epidermal Growth Factor Receptor (EGFR) Reduces Lipopolysaccharide (LPS)-Induced Activation and Inflammatory Cytokines in Hepatic Stellate Cells In Vitro

(2018) Yuanyuan Qian et al.   MEDICAL SCIENCE MONITOR

Paired related homeobox protein 1 regulates PDGF-induced chemotaxis of hepatic stellate cells in liver fibrosis

(2017) Jin Gong et al.   LABORATORY INVESTIGATION

TWEAK/Fn14 promotes pro-inflammatory cytokine secretion in hepatic stellate cells via NF-κB/STAT3 pathways

(2017) Aixiu Wang et al.   MOLECULAR IMMUNOLOGY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases

(2017) Michael Croft et al.   Nature Reviews Rheumatology

TWEAK increases SIRT1 expression and promotes p53 deacetylation affecting human hepatic stellate cell senescence

(2016) Feng Zhang et al.   CELL BIOLOGY INTERNATIONAL

An overview of effective therapies and recent advances in biomarkers for chronic liver diseases and associated liver cancer

(2015) Reshmi Chatterjee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

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(2015) Christian Trautwein et al.   JOURNAL OF HEPATOLOGY

Matrix metalloproteinase-9 is up-regulated by CCL19/CCR7 interaction via PI3K/Akt pathway and is involved in CCL19-driven BMSCs migration

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Up-regulation of miR-200b in biliary atresia patients accelerates proliferation and migration of hepatic stallate cells by activating PI3K/Akt signaling

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IL-30 (IL27p28) attenuates liver fibrosis through inducing NKG2D-rae1 interaction between NKT and activated hepatic stellate cells in mice

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S-adenosylmethionine inhibits the activated phenotype of human hepatic stellate cells via Rac1 and Matrix metalloproteinases

(2014) Feng Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The TWEAK Receptor Fn14 Is an Src-Inducible Protein and a Positive Regulator of Src-Driven Cell Invasion

(2014) Emily Cheng et al.   MOLECULAR CANCER RESEARCH

TWEAK/Fn14 axis: The current paradigm of tissue injury-inducible function in the midst of complexities

(2014) Linda C. Burkly   SEMINARS IN IMMUNOLOGY

TWEAK transactivation of the epidermal growth factor receptor mediates renal inflammation

(2013) Sandra Rayego-Mateos et al.   JOURNAL OF PATHOLOGY

Macrophage therapy for murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function

(2011) James A. Thomas et al.   HEPATOLOGY

Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin αVβ3 engagement and PI3K/pAkt/NFκB signaling

(2011) Raquel Urtasun et al.   HEPATOLOGY

Targeting Src family kinases in anti-cancer therapies: turning promise into triumph

(2011) Siyuan Zhang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia

(2009) Ana B. Sanz et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CD95 Ligand Is a Proliferative and Antiapoptotic Signal in Quiescent Hepatic Stellate Cells

(2008) Roland Reinehr et al.   GASTROENTEROLOGY