LAMB3 mediates apoptotic, proliferative, invasive, and metastatic behaviors in pancreatic cancer by regulating the PI3K/Akt signaling pathway

POU5F1B promotes hepatocellular carcinoma proliferation by activating AKT

(2018) Yaozhen Pan et al.   BIOMEDICINE & PHARMACOTHERAPY

Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway

(2018) Syue-Ting Chen et al.   ONCOGENE

Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling

(2018) Qingcai Meng et al.   ONCOGENE

Combination of PI3K/Akt Pathway Inhibition and Plk1 Depletion Can Enhance Chemosensitivity to Gemcitabine in Pancreatic Carcinoma

(2018) Yonghuan Mao et al.   Translational Oncology

LAMB3 mediates metastatic tumor behavior in papillary thyroid cancer by regulating c-MET/Akt signals

(2018) Seung-Nam Jung et al.   Scientific Reports

Oncogenic TRIM31 confers gemcitabine resistance in pancreatic cancer via activating the NF-κB signaling pathway

(2018) Chao Yu et al.   Theranostics

Eupatilin inhibits angiogenesis-mediated human hepatocellular metastasis by reducing MMP-2 and VEGF signaling

(2018) Jun Yeon Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases

(2018) Jiaxin Liang et al.   CANCER RESEARCH

Imbalance of the reciprocally inhibitory loop between the ubiquitin-specific protease USP43 and EGFR/PI3K/AKT drives breast carcinogenesis

(2018) Lin He et al.   CELL RESEARCH

MiR-543 Promotes Migration, Invasion and Epithelial-Mesenchymal Transition of Esophageal Cancer Cells by Targeting Phospholipase A2 Group IVA

(2018) Huaying Zhao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Concurrent HER or PI3K Inhibition Potentiates the Antitumor Effect of the ERK Inhibitor Ulixertinib in Preclinical Pancreatic Cancer Models

(2018) Hongmei Jiang et al.   MOLECULAR CANCER THERAPEUTICS

International Validation of the Eighth Edition of the American Joint Committee on Cancer (AJCC) TNM Staging System in Patients With Resected Pancreatic Cancer

(2018) Stijn van Roessel et al.   JAMA Surgery

HIF-3α Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC–ROCK1 Signaling Pathway

(2017) Xianfei Zhou et al.   MOLECULAR CANCER RESEARCH

Upregulated LAMB3 increases proliferation and metastasis in thyroid cancer

(2017) Yinghao Wang et al.   OncoTargets and Therapy

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

A uniqueLAMB3splice-site mutation with founder effect from the Balkans causes lethal epidermolysis bullosa in several European countries

(2016) B. Mayer et al.   BRITISH JOURNAL OF DERMATOLOGY

Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation

(2016) Yan Wang et al.   CANCER RESEARCH

miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3

(2016) Ying Zhou et al.   CANCER RESEARCH

Carriers with functional null mutations in LAMA3 have localized enamel abnormalities due to haploinsufficiency

(2016) Katarzyna B Gostyńska et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human pancreatic cancer cells

(2015) Xu Li et al.   CANCER LETTERS

Phase I Trial of the Pan-PI3K Inhibitor Pilaralisib (SAR245408/XL147) in Patients with Chronic Lymphocytic Leukemia (CLL) or Relapsed/Refractory Lymphoma

(2015) J. R. Brown et al.   CLINICAL CANCER RESEARCH

Membrane-type matrix metalloproteinases: Their functions and regulations

(2015) Yoshifumi Itoh   MATRIX BIOLOGY

The PI3K/AKT/mTOR interactive pathway

(2015) Tulin Ersahin et al.   Molecular BioSystems

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway

(2015) ZHIMING ZHAO et al.   Molecular Medicine Reports

SMAD4 Loss triggers the phenotypic changes of pancreatic ductal adenocarcinoma cells

(2014) Yu-Wen Chen et al.   BMC CANCER

Activation of glucagon-like peptide-1 receptor inhibits tumourigenicity and metastasis of human pancreatic cancer cells via PI3K/Akt pathway

(2014) H. Zhao et al.   DIABETES OBESITY & METABOLISM

Embelin Suppresses Growth of Human Pancreatic Cancer Xenografts, and Pancreatic Cancer Cells Isolated from KrasG12D Mice by Inhibiting Akt and Sonic Hedgehog Pathways

(2014) Minzhao Huang et al.   PLoS One

PI3K/AKT/mTOR Signaling is Involved in (-)-Epigallocatechin-3-Gallate-Induced Apoptosis of Human Pancreatic Carcinoma Cells

(2013) Shi Liu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

(2013) Akintunde Akinleye et al.   Journal of Hematology & Oncology

Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT

(2013) Jiaxin Tan et al.   TOXICOLOGY LETTERS

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology