Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Deconvolution of transcriptomes and miRNomes by independent component analysis provides insights into biological processes and clinical outcomes of melanoma patients
Authors
Keywords
Independent component analysis, Deconvolution, Transcriptomics, Cancer, Survival analysis
Journal
BMC Medical Genomics
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-18
DOI
10.1186/s12920-019-0578-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Assessing reproducibility of matrix factorization methods in independent transcriptomes
- (2019) Laura Cantini et al. BIOINFORMATICS
- Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment
- (2019) Anne Dirkse et al. Nature Communications
- MicroRNAs as modulators of T cell functions in cancer
- (2018) Stefan Emming et al. CANCER LETTERS
- Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade
- (2017) Thomas B. Huffaker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions
- (2017) Chih-Hung Chou et al. NUCLEIC ACIDS RESEARCH
- miR clusters target cellular functional complexes by defining their degree of regulatory freedom
- (2016) Jörg Haier et al. CANCER AND METASTASIS REVIEWS
- Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer
- (2016) Philip D. Dunne et al. CLINICAL CANCER RESEARCH
- microRNAs in the Same Clusters Evolve to Coordinately Regulate Functionally Related Genes
- (2016) Yirong Wang et al. MOLECULAR BIOLOGY AND EVOLUTION
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- The genomic landscape of cutaneous melanoma
- (2016) Tongwu Zhang et al. Pigment Cell & Melanoma Research
- Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
- (2016) I. Tirosh et al. SCIENCE
- Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome
- (2016) Katey S.S. Enfield et al. Oncotarget
- Fast dimension reduction and integrative clustering of multi-omics data using low-rank approximation: application to cancer molecular classification
- (2015) Dingming Wu et al. BMC GENOMICS
- Genomic Classification of Cutaneous Melanoma
- (2015) Rehan Akbani et al. CELL
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Identification of a chrXq27.3 microRNA cluster associated with early relapse in advanced stage ovarian cancer patients
- (2015) Marina Bagnoli et al. Oncotarget
- Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 Increases Neovascularization and Blood Flow Recovery After Ischemia
- (2014) Sabine M.J. Welten et al. CIRCULATION RESEARCH
- Two-Stage, In Silico Deconvolution of the Lymphocyte Compartment of the Peripheral Whole Blood Transcriptome in the Context of Acute Kidney Allograft Rejection
- (2014) Casey P. Shannon et al. PLoS One
- Intratumor heterogeneity alters most effective drugs in designed combinations
- (2014) B. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- miR-155 augments CD8+T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γccytokines
- (2014) Yun Ji et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Independent Component Analysis Uncovers the Landscape of the Bladder Tumor Transcriptome and Reveals Insights into Luminal and Basal Subtypes
- (2014) Anne Biton et al. Cell Reports
- Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers
- (2013) Saurabh V Laddha et al. Biology Direct
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function
- (2013) Petr V. Nazarov et al. NUCLEIC ACIDS RESEARCH
- Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma
- (2013) P N Valdmanis et al. ONCOGENE
- Inferring tumour purity and stromal and immune cell admixture from expression data
- (2013) Kosuke Yoshihara et al. Nature Communications
- Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction
- (2013) Gerald Quon et al. Genome Medicine
- Blind source separation methods for deconvolution of complex signals in cancer biology
- (2012) Andrei Zinovyev et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Silencing of a large microRNA cluster on human chromosome 14q32 in melanoma: biological effects of mir-376a and mir-376c on insulin growth factor 1 receptor
- (2012) Liron Zehavi et al. Molecular Cancer
- A flexible R package for nonnegative matrix factorization
- (2010) Renaud Gaujoux et al. BMC BIOINFORMATICS
- Melanoma MicroRNA Signature Predicts Post-Recurrence Survival
- (2010) M. F. Segura et al. CLINICAL CANCER RESEARCH
- Differential expression analysis for sequence count data
- (2010) Simon Anders et al. GENOME BIOLOGY
- Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
- (2009) D. Bogunovic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Merging two gene-expression studies via cross-platform normalization
- (2008) Andrey A. Shabalin et al. BIOINFORMATICS
- A skin microRNA promotes differentiation by repressing ‘stemness’
- (2008) Rui Yi et al. NATURE
- Gene Expression Data Classification Using Consensus Independent Component Analysis
- (2008) Chun-Hou Zheng et al. GENOMICS PROTEOMICS & BIOINFORMATICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now