Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative period

Phosphodiesterase-5 inhibition reduces postoperative metastatic disease by targeting surgery-induced myeloid derived suppressor cell-dependent inhibition of Natural Killer cell cytotoxicity

(2018) Lee-Hwa Tai et al.   OncoImmunology

Combining surgery and immunotherapy: turning an immunosuppressive effect into a therapeutic opportunity

(2018) Orneala Bakos et al.   Journal for ImmunoTherapy of Cancer

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

(2018) Xavier Michelet et al.   NATURE IMMUNOLOGY

Dysregulated cellular functions and cell stress pathways provide critical cues for activating and targeting natural killer cells to transformed and infected cells

(2017) David H. Raulet et al.   IMMUNOLOGICAL REVIEWS

NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine

(2017) Almohanad A. Alkayyal et al.   Cancer Immunology Research

Immunosurveillance and immunotherapy of tumors by innate immune cells

(2016) Alexandre Iannello et al.   CURRENT OPINION IN IMMUNOLOGY

The influence of myeloid-derived suppressor cells on angiogenesis and tumor growth after cancer surgery

(2016) Jun Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

(2015) F. Hossain et al.   Cancer Immunology Research

Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Oxidized Lipids Block Antigen Cross-Presentation by Dendritic Cells in Cancer

(2014) W. Cao et al.   JOURNAL OF IMMUNOLOGY

Maraba MG1 Virus Enhances Natural Killer Cell Function via Conventional Dendritic Cells to Reduce Postoperative Metastatic Disease

(2014) Jiqing Zhang et al.   MOLECULAR THERAPY

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

(2014) Lee-Hwa Tai et al.   Jove-Journal of Visualized Experiments

The Central Role of Arginine Catabolism in T-Cell Dysfunction and Increased Susceptibility to Infection After Physical Injury

(2013) Xinmei Zhu et al.   ANNALS OF SURGERY

Perioperative Influenza Vaccination Reduces Postoperative Metastatic Disease by Reversing Surgery-Induced Dysfunction in Natural Killer Cells

(2013) L.-H. Tai et al.   CLINICAL CANCER RESEARCH

Myeloid-derived suppressor cells in cancer: recent progress and prospects

(2013) Yazan S Khaled et al.   IMMUNOLOGY AND CELL BIOLOGY

Surgical Stress Promotes the Development of Cancer Metastases by a Coagulation-Dependent Mechanism Involving Natural Killer Cells in a Murine Model

(2012) Rashmi Seth et al.   ANNALS OF SURGERY

Preventing Postoperative Metastatic Disease by Inhibiting Surgery-Induced Dysfunction in Natural Killer Cells

(2012) L.-H. Tai et al.   CANCER RESEARCH

CD36 as a target to prevent cardiac lipotoxicity and insulin resistance

(2012) Jan F.C. Glatz et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Myeloid-derived suppressor cells are implicated in regulating permissiveness for tumor metastasis during mouse gestation

(2011) Laetitia A. Mauti et al.   JOURNAL OF CLINICAL INVESTIGATION

Deletion of the murine scavenger receptor CD68

(2011) Li Song et al.   JOURNAL OF LIPID RESEARCH

Effect of Ly49 Haplotype Variance on NK Cell Function and Education

(2010) R. Patel et al.   JOURNAL OF IMMUNOLOGY

Improving Survival Rates in Two Models of Spontaneous Postoperative Metastasis in Mice by Combined Administration of a β-Adrenergic Antagonist and a Cyclooxygenase-2 Inhibitor

(2010) Ariella Glasner et al.   JOURNAL OF IMMUNOLOGY

Lipid accumulation and dendritic cell dysfunction in cancer

(2010) Donna L Herber et al.   NATURE MEDICINE

Immune perturbations in patients along the perioperative period: Alterations in cell surface markers and leukocyte subtypes before and after surgery

(2009) Inbal Bartal et al.   BRAIN BEHAVIOR AND IMMUNITY

NK cell education: not an on-off switch but a tunable rheostat

(2009) Petter Brodin et al.   TRENDS IN IMMUNOLOGY

Perioperative Use of β-blockers and COX-2 Inhibitors May Improve Immune Competence and Reduce the Risk of Tumor Metastasis

(2008) Marganit Benish et al.   ANNALS OF SURGICAL ONCOLOGY

NK cell-mediated targeting of human cancer and possibilities for new means of immunotherapy

(2008) Karl-Johan Malmberg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways: Fig. 1.

(2008) Ira J. Goldberg et al.   JOURNAL OF LIPID RESEARCH