Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression
Authors
Keywords
-
Journal
AGING CELL
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-09-08
DOI
10.1111/acel.13027
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis
- (2019) Stefania Raimondo et al. Journal of Hematology & Oncology
- Metabolic Reprogramming in Breast Cancer and Its Therapeutic Implications
- (2019) Nishant Gandhi et al. Cells
- Androgen Deprivation Therapy Potentiates the Efficacy of Vascular Targeted Photodynamic Therapy of Prostate Cancer Xenografts
- (2018) Kwanghee Kim et al. CLINICAL CANCER RESEARCH
- Understanding the tumor immune microenvironment (TIME) for effective therapy
- (2018) Mikhail Binnewies et al. NATURE MEDICINE
- Defining and Understanding Adaptive Resistance in Cancer Immunotherapy
- (2018) Tae Kon Kim et al. TRENDS IN IMMUNOLOGY
- The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1
- (2018) Boyi Zhang et al. Nature Communications
- Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap
- (2018) Wantong Song et al. Nature Communications
- CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade
- (2018) Limo Chen et al. Cancer Discovery
- PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer
- (2018) Magalie Dosset et al. OncoImmunology
- Cellular Senescence: The Sought or the Unwanted?
- (2018) Yu Sun et al. TRENDS IN MOLECULAR MEDICINE
- Phase III Study Comparing a Reduced Dose of Cabazitaxel (20 mg/m2) and the Currently Approved Dose (25 mg/m2) in Postdocetaxel Patients With Metastatic Castration-Resistant Prostate Cancer—PROSELICA
- (2017) Mario Eisenberger et al. JOURNAL OF CLINICAL ONCOLOGY
- Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
- (2017) Ok Hee Jeon et al. NATURE MEDICINE
- Humanized mouse model supports development, function, and tissue residency of human natural killer cells
- (2017) Dietmar Herndler-Brandstetter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amphiregulin contained in NSCLC-exosomes induces osteoclast differentiation through the activation of EGFR pathway
- (2017) Simona Taverna et al. Scientific Reports
- Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model
- (2017) Ahmed Z. El-Hashim et al. Scientific Reports
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
- (2016) Christina Pfirschke et al. IMMUNITY
- Chronic myelogenous leukaemia exosomes modulate bone marrow microenvironment through activation of epidermal growth factor receptor
- (2016) Chiara Corrado et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
- (2016) Y Sun et al. ONCOGENE
- Senescent intimal foam cells are deleterious at all stages of atherosclerosis
- (2016) B. G. Childs et al. SCIENCE
- Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse
- (2016) Marco Demaria et al. Cancer Discovery
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents
- (2015) Lorenzo Galluzzi et al. CANCER CELL
- Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2R null Immunodeficient Mice
- (2015) M. F. Sanmamed et al. CANCER RESEARCH
- Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair
- (2015) Dietmar M.W. Zaiss et al. IMMUNITY
- Therapy-induced tumour secretomes promote resistance and tumour progression
- (2015) Anna C. Obenauf et al. NATURE
- Adaptive Immune Resistance: How Cancer Protects from Immune Attack
- (2015) A. Ribas Cancer Discovery
- Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue – a review
- (2014) Nickolay Fedchenko et al. Diagnostic Pathology
- Cellular senescence and its effector programs
- (2014) R. Salama et al. GENES & DEVELOPMENT
- Amphiregulin
- (2014) Carmen Berasain et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Trial watch: Dendritic cell-based anticancer therapy
- (2014) Norma Bloy et al. OncoImmunology
- Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor
- (2013) Dietmar M.W. Zaiss et al. IMMUNITY
- Influence of tumour micro-environment heterogeneity on therapeutic response
- (2013) Melissa R. Junttila et al. NATURE
- Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung Tumors
- (2013) E. A. Akbay et al. Cancer Discovery
- Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial†
- (2012) M. Reck et al. ANNALS OF ONCOLOGY
- Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
- (2012) Yu Sun et al. NATURE MEDICINE
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- Feedback regulation of EGFR signalling: decision making by early and delayed loops
- (2011) Roi Avraham et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA Damage-Mediated Induction of a Chemoresistant Niche
- (2010) Luke A. Gilbert et al. CELL
- Entrez Gene: gene-centered information at NCBI
- (2010) D. Maglott et al. NUCLEIC ACIDS RESEARCH
- The Universal Protein Resource (UniProt) in 2010
- (2009) NUCLEIC ACIDS RESEARCH
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
- (2008) Juan C. Acosta et al. CELL
- Human Protein Reference Database--2009 update
- (2008) T. S. Keshava Prasad et al. NUCLEIC ACIDS RESEARCH
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search