The Impact of the Adipose Organ Plasticity on Inflammation and Cancer Progression

Brown and Brite: The Fat Soldiers in the Anti-obesity Fight

(2019) Shireesh Srivastava et al.   Frontiers in Physiology

Leptin and brain–adipose crosstalks

(2018) Alexandre Caron et al.   NATURE REVIEWS NEUROSCIENCE

Obesity and Pancreatic Cancer

(2018) Mu Xu et al.   PANCREAS

Macrophage polarization and meta-inflammation

(2018) Chuan Li et al.   Translational Research

Pink Adipocytes

(2018) Saverio Cinti   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Obesity and cancer risk: Emerging biological mechanisms and perspectives

(2018) Konstantinos I. Avgerinos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The obese adipose tissue microenvironment in cancer development and progression

(2018) Daniela F. Quail et al.   Nature Reviews Endocrinology

Adipose stromal cell targeting suppresses prostate cancer epithelial-mesenchymal transition and chemoresistance

(2018) Fei Su et al.   ONCOGENE

Plasticity of Adipose Tissue-Derived Stem Cells and Regulation of Angiogenesis

(2018) Yulia A. Panina et al.   Frontiers in Physiology

Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion

(2018) Lauren E. Hillers et al.   NEOPLASIA

Intentional Weight Loss and Endometrial Cancer Risk

(2017) Juhua Luo et al.   JOURNAL OF CLINICAL ONCOLOGY

Association Between Weight Loss and the Risk of Cancer after Bariatric Surgery

(2017) Daniel P. Schauer et al.   Obesity

Human adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting

(2017) Francesca Paino et al.   Cell Death & Disease

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

(2017) Rebecca C. Schugar et al.   Cell Reports

The dark side of browning

(2017) Kirstin A. Tamucci et al.   Protein & Cell

Adipocytes and Macrophages Interplay in the Orchestration of Tumor Microenvironment: New Implications in Cancer Progression

(2017) Luís Henrique Corrêa et al.   Frontiers in Immunology

Adipokines (Leptin, Adiponectin, Resistin) Differentially Regulate All Hormonal Cell Types in Primary Anterior Pituitary Cell Cultures from Two Primate Species

(2017) André Sarmento-Cabral et al.   Scientific Reports

The role of the brown adipose tissue in β3-adrenergic receptor activation-induced sleep, metabolic and feeding responses

(2017) Éva Szentirmai et al.   Scientific Reports

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

From obesity to cancer: a review on proposed mechanisms

(2016) Zoya Tahergorabi et al.   CELL BIOCHEMISTRY AND FUNCTION

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals

(2016) Yi Zhu et al.   Cell Metabolism

Adipose tissue macrophages: going off track during obesity

(2016) Lily Boutens et al.   DIABETOLOGIA

The role of adipose tissue in cancer-associated cachexia

(2016) Janina A Vaitkus et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning

(2016) Dianxin Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Thyroid hormones induce browning of white fat

(2016) Noelia Martínez-Sánchez et al.   JOURNAL OF ENDOCRINOLOGY

Effects of physical exercise on myokines expression and brown adipose-like phenotype modulation in rats fed a high-fat diet

(2016) Sílvia Rocha-Rodrigues et al.   LIFE SCIENCES

Body Fatness and Cancer — Viewpoint of the IARC Working Group

(2016) Béatrice Lauby-Secretan et al.   NEW ENGLAND JOURNAL OF MEDICINE

CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment

(2016) Tao Zhang et al.   Nature Communications

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

(2016) Juliane Weiner et al.   Scientific Reports

Novel Browning Agents, Mechanisms, and Therapeutic Potentials of Brown Adipose Tissue

(2016) Umesh D. Wankhade et al.   Biomed Research International

Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance

(2016) S. Nishimoto et al.   Science Advances

Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis - A Cohort Study in a Group of Thyroid Carcinoma Patients

(2016) Evie P. M. Broeders et al.   PLoS One

Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes

(2016) María Calderon-Dominguez et al.   PLoS One

An ERβ agonist induces browning of subcutaneous abdominal fat pad in obese female mice

(2016) Yi-fei Miao et al.   Scientific Reports

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

(2015) Amaia Rodríguez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Role of Exercise in the Activation of Brown Adipose Tissue

(2015) Guillermo Sanchez-Delgado et al.   ANNALS OF NUTRITION AND METABOLISM

Impact of the Obesity Epidemic on Cancer

(2015) Pamela J. Goodwin et al.   Annual Review of Medicine

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations

(2015) Kristin I. Stanford et al.   DIABETES

Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity

(2015) Injae Hwang et al.   FASEB JOURNAL

Microbiota depletion promotes browning of white adipose tissue and reduces obesity

(2015) Nicolas Suárez-Zamorano et al.   NATURE MEDICINE

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

(2015) Ji Miao et al.   Nature Communications

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity

(2015) Xiao-Rong Peng et al.   Frontiers in Endocrinology

Paracrine Interactions between Adipocytes and Tumor Cells Recruit and Modify Macrophages to the Mammary Tumor Microenvironment: The Role of Obesity and Inflammation in Breast Adipose Tissue

(2015) Ana Santander et al.   Cancers

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia

(2014) Michele Petruzzelli et al.   Cell Metabolism

Prdm16 Is Required for the Maintenance of Brown Adipocyte Identity and Function in Adult Mice

(2014) Matthew J. Harms et al.   Cell Metabolism

MECHANISMS IN ENDOCRINOLOGY: White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ

(2014) Antonio Giordano et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Obesity and cancer—mechanisms underlying tumour progression and recurrence

(2014) Jiyoung Park et al.   Nature Reviews Endocrinology

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis

(2014) Miyako Tanaka et al.   Nature Communications

FGF21 as a Hepatokine, Adipokine, and Myokine in Metabolism and Diseases

(2014) Nobuyuki Itoh   Frontiers in Endocrinology

Adipose tissue and adipocytes support tumorigenesis and metastasis

(2013) Kristin M. Nieman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Turning WAT into BAT: a review on regulators controlling the browning of white adipocytes

(2013) Kinyui Alice Lo et al.   BIOSCIENCE REPORTS

Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment

(2013) Anthony J. Apostoli et al.   INTERNATIONAL JOURNAL OF CANCER

Bi-directional interconversion of brite and white adipocytes

(2013) Matthias Rosenwald et al.   NATURE CELL BIOLOGY

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

Adipose tissue browning and metabolic health

(2013) Alexander Bartelt et al.   Nature Reviews Endocrinology

Obesity and prostate cancer: gene expression signature of human periprostatic adipose tissue

(2012) Ricardo Ribeiro et al.   BMC Medicine

PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein

(2012) Haruya Ohno et al.   Cell Metabolism

Pten Positively Regulates Brown Adipose Function, Energy Expenditure, and Longevity

(2012) Ana Ortega-Molina et al.   Cell Metabolism

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis

(2012) Luis Varela et al.   EMBO REPORTS

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes

(2012) A. Vitali et al.   JOURNAL OF LIPID RESEARCH

A systematic review of the impact of weight loss on cancer incidence and mortality

(2012) S. Birks et al.   Obesity Reviews

Development of insulin resistance in mice lacking PGC-1  in adipose tissues

(2012) S. Kleiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of thiazolidinediones on human bone marrow stromal cell differentiation in vitro and in thiazolidinedione-treated patients with type 2 diabetes

(2012) George R. Beck et al.   Translational Research

Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues

(2011) Tomas B. Waldén et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

(2011) B. Dirat et al.   CANCER RESEARCH

Adipocytes as a new source of catecholamine production

(2011) Peter Vargovic et al.   FEBS LETTERS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Reduced Energy Expenditure and Increased Inflammation Are Early Events in the Development of Ovariectomy-Induced Obesity

(2009) Nicole H. Rogers et al.   ENDOCRINOLOGY

C/EBP  and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor   Agonists

(2009) C. Vernochet et al.   MOLECULAR AND CELLULAR BIOLOGY

A Functional Interaction between RIP140 and PGC-1  Regulates the Expression of the Lipid Droplet Protein CIDEA

(2008) M. Hallberg et al.   MOLECULAR AND CELLULAR BIOLOGY

Macrophage polarization in tumour progression

(2008) Antonio Sica et al.   SEMINARS IN CANCER BIOLOGY