Bile canaliculi formation and biliary transport in 3D sandwich-cultured hepatocytes in dependence of the extracellular matrix composition

Bile canalicular dynamics in hepatocyte sandwich cultures

(2015) Raymond Reif et al.   ARCHIVES OF TOXICOLOGY

Epithelial polarity – Generating and integrating signals from the ECM with integrins

(2015) Aki Manninen   EXPERIMENTAL CELL RESEARCH

Toxicogenomics directory of chemically exposed human hepatocytes

(2014) Marianna Grinberg et al.   ARCHIVES OF TOXICOLOGY

Featured Article: Isolation, characterization, and cultivation of human hepatocytes and non-parenchymal liver cells

(2014) Elisa Pfeiffer et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The unique polarity phenotype of hepatocytes

(2014) Anne Müsch   EXPERIMENTAL CELL RESEARCH

Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

(2013) L. Schyschka et al.   ARCHIVES OF TOXICOLOGY

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Sandwich-cultured hepatocytes: utility forin vitroexploration of hepatobiliary drug disposition and drug-induced hepatotoxicity

(2013) Tom De Bruyn et al.   Expert Opinion on Drug Metabolism & Toxicology

Analysis of drug metabolism activities in a miniaturized liver cell bioreactor for use in pharmacological studies

(2012) Stefan A. Hoffmann et al.   BIOTECHNOLOGY AND BIOENGINEERING

Sandwich-cultured hepatocytes: anin vitromodel to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity

(2010) Brandon Swift* et al.   DRUG METABOLISM REVIEWS

Influence of Seeding Density and Extracellular Matrix on Bile Acid Transport and Mrp4 Expression in Sandwich-Cultured Mouse Hepatocytes

(2009) Brandon Swift et al.   MOLECULAR PHARMACEUTICS

Use of Sandwich-Cultured Human Hepatocytes to Predict Biliary Clearance of Angiotensin II Receptor Blockers and HMG-CoA Reductase Inhibitors

(2008) K. Abe et al.   DRUG METABOLISM AND DISPOSITION