Cannabinoid Receptor 1 Blockade Attenuates Obesity and Adipose Tissue Type 1 Inflammation Through miR-30e-5p Regulation of Delta-Like-4 in Macrophages and Consequently Downregulation of Th1 Cells

MicroRNA-30 modulates metabolic inflammation by regulating Notch signaling in adipose tissue macrophages

(2018) Kathryn Miranda et al.   INTERNATIONAL JOURNAL OF OBESITY

miR-466a Targeting of TGF-β2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation

(2018) William Becker et al.   Frontiers in Immunology

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages

(2017) Inigo Ruiz de Azua et al.   JOURNAL OF CLINICAL INVESTIGATION

Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence

(2017) Jacqueline Kerr et al.   LANCET ONCOLOGY

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity

(2017) Pegah Mehrpouya-Bahrami et al.   Scientific Reports

Delta-Like Ligand 4-Notch Signaling in Macrophage Activation

(2016) Toshiaki Nakano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miRNA-30e regulates abnormal differentiation of small intestinal epithelial cells in diabetic mice by downregulating Dll4 expression

(2016) Ti-Dong Shan et al.   CELL PROLIFERATION

Adipose tissue macrophages: going off track during obesity

(2016) Lily Boutens et al.   DIABETOLOGIA

MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice

(2016) Sara Irani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-30 Promotes Thermogenesis and the Development of Beige Fat by Targeting RIP140

(2015) Fang Hu et al.   DIABETES

Blocking high-fat diet-induced obesity, insulin resistance and fatty liver by overexpression of Il-13 gene in mice

(2015) P Darkhal et al.   INTERNATIONAL JOURNAL OF OBESITY

CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages

(2015) Chunxing Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local Proliferation of Macrophages Contributes to Obesity-Associated Adipose Tissue Inflammation

(2014) Shinya U. Amano et al.   Cell Metabolism

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity

(2014) Pengpeng Bi et al.   NATURE MEDICINE

Leptin: 20 years later

(2014) Norra MacReady   Lancet Diabetes & Endocrinology

Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4 + T Cells in Mice

(2013) David L. Morris et al.   DIABETES

Expression profiles of miRNAs in polarized macrophages

(2013) YINGYING ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Long-term Drug Treatment for Obesity

(2013) Susan Z. Yanovski et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis

(2012) G. Bridge et al.   BLOOD

Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections

(2012) Miguel Galarraga et al.   JOURNAL OF LIPID RESEARCH

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

(2012) Haixia Xu et al.   NATURE IMMUNOLOGY

The Notch signalling system: recent insights into the complexity of a conserved pathway

(2012) K. G. Guruharsha et al.   NATURE REVIEWS GENETICS

Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

(2012) D. Fukuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In obesity and weight loss, all roads lead to the mighty macrophage

(2010) Alex Red Eagle et al.   JOURNAL OF CLINICAL INVESTIGATION

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE