MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice

PCSK9 inhibition: the way forward in the treatment of dyslipidemia

(2015) Robert M. Stoekenbroek et al.   BMC Medicine

Role of microRNA-30c in lipid metabolism, adipogenesis, cardiac remodeling and cancer

(2015) Sara Irani et al.   CURRENT OPINION IN LIPIDOLOGY

The impact of proprotein convertase subtilisin-kexin type 9 serine protease inhibitors on lipid levels and outcomes in patients with primary hypercholesterolaemia: a network meta-analysis

(2015) Michael J. Lipinski et al.   EUROPEAN HEART JOURNAL

PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial

(2015) Frederick J Raal et al.   LANCET

Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events

(2015) Jennifer G. Robinson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Breakers and blockers--miRNAs at work

(2015) E. Izaurralde   SCIENCE

2013 ACC/AHA cholesterol treatment guideline: Paradigm shifts in managing atherosclerotic cardiovascular disease risk

(2015) Jonathan B. Finkel et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Lomitapide and Mipomersen

(2014) Daniel J. Rader et al.   CIRCULATION

Non-traditional Dosing of Statins in Statin-Intolerant Patients—Is It Worth a Try?

(2014) Marc-Andre Cornier et al.   Current Atherosclerosis Reports

Development of microRNA therapeutics is coming of age

(2014) E. van Rooij et al.   EMBO Molecular Medicine

Curing Atherosclerosis Should Be the Next Major Cardiovascular Prevention Goal

(2014) Jennifer G. Robinson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anti-PCSK9 Antibody Effectively Lowers Cholesterol in Patients With Statin Intolerance

(2014) Erik Stroes et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Impaired Cholesterol Metabolism and Enhanced Atherosclerosis in Clock Mutant Mice

(2013) Xiaoyue Pan et al.   CIRCULATION

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

(2013) David C. Goff et al.   CIRCULATION

Microsomal transfer protein inhibition in humans

(2013) Marina Cuchel et al.   CURRENT OPINION IN LIPIDOLOGY

Roadmap of miR-122-related clinical application from bench to bedside

(2013) Zhihua Qiu et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

First microRNA mimic enters clinic

(2013) Aaron Bouchie   NATURE BIOTECHNOLOGY

MicroRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion

(2013) James Soh et al.   NATURE MEDICINE

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

Increased Intestinal Lipid Absorption Caused by Ire1β Deficiency Contributes to Hyperlipidemia and Atherosclerosis in Apolipoprotein E–Deficient Mice

(2012) Jahangir Iqbal et al.   CIRCULATION RESEARCH

Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study

(2012) Marina Cuchel et al.   LANCET

Multiple functions of microsomal triglyceride transfer protein

(2012) M Mahmood Hussain et al.   Nutrition & Metabolism

New Lipid Modulating Drugs: The Role of Microsomal Transport Protein Inhibitors

(2011) Manfredi Rizzo et al.   CURRENT PHARMACEUTICAL DESIGN

Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice

(2011) Irani Khatun et al.   HEPATOLOGY

MicroRNAs in lipid metabolism

(2010) Carlos Fernández-Hernando et al.   CURRENT OPINION IN LIPIDOLOGY

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

New approaches to target microsomal triglyceride transfer protein

(2008) Mohammed Mahmood Hussain et al.   CURRENT OPINION IN LIPIDOLOGY

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

(2008) Frederick F Samaha et al.   Nature clinical practice. Cardiovascular medicine