Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

Expression of Notch receptors and ligands on immature and mature T cells

(2012) Akemi Koyanagi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification

(2011) Sophie E.P. New et al.   CIRCULATION RESEARCH

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner

(2011) Utpal B Pajvani et al.   NATURE MEDICINE

Functions of Notch Signaling in the Immune System: Consensus and Controversies

(2010) Julie S. Yuan et al.   Annual Review of Immunology

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Inflammation and the Osteogenic Regulation of Vascular Calcification

(2010) Jian-Su Shao et al.   HYPERTENSION

Notch Signaling in the Immune System

(2010) Freddy Radtke et al.   IMMUNITY

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chronic DLL4 blockade induces vascular neoplasms

(2010) Minhong Yan et al.   NATURE

Blockade of Delta-Like Ligand 4 Signaling Inhibits Both Growth and Angiogenesis of Pancreatic Cancer

(2010) Hidekazu Oishi et al.   PANCREAS

Notch Signaling Induces Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells

(2009) Takehisa Shimizu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Macrophage Diversity and Polarization in Atherosclerosis

(2009) Alberto Mantovani et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

(2009) S. Yamanda et al.   BLOOD

TNFα promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-κB signaling pathway

(2009) Katrin Hess et al.   BONE

Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease

(2009) Elena Aikawa et al.   CIRCULATION

Hepatic monocyte chemoattractant protein-1 is upregulated by dietary cholesterol and contributes to liver steatosis

(2009) Anna Rull et al.   CYTOKINE

Notch1 upregulates LPS-induced macrophage activation by increasing NF-κB activity

(2009) Eva Monsalve et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential regulation of splenic CD8- dendritic cells and marginal zone B cells by Notch ligands

(2009) C. Sekine et al.   INTERNATIONAL IMMUNOLOGY

Cutting Edge: Plasmacytoid Dendritic Cells Induce IL-10 Production in T Cells via the Delta-Like-4/Notch Axis

(2009) N. Kassner et al.   JOURNAL OF IMMUNOLOGY

Notch-1 activates estrogen receptor-α-dependent transcription via IKKα in breast cancer cells

(2009) L Hao et al.   ONCOGENE

Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes

(2009) Isabel Rubio-Aliaga et al.   PLoS One

Notch Signaling in Leukemia

(2008) Jon C. Aster et al.   Annual Review of Pathology-Mechanisms of Disease

Dietary Cholesterol Worsens Adipose Tissue Macrophage Accumulation and Atherosclerosis in Obese LDL Receptor–Deficient Mice

(2008) Savitha Subramanian et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity

(2008) Kihwa Kang et al.   Cell Metabolism

Obesity-Related Upregulation of Monocyte Chemotactic Factors in Adipocytes: Involvement of Nuclear Factor- B and c-Jun NH2-Terminal Kinase Pathways

(2008) P. Jiao et al.   DIABETES

Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis

(2008) Atsuki Fukushima et al.   IMMUNOLOGY LETTERS

Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice

(2008) Y. Moriyama et al.   INTERNATIONAL IMMUNOLOGY

Oxidation, Inflammation, and Aortic Valve Calcification

(2008) Dwight A. Towler   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rapid regression of atherosclerosis: insights from the clinical and experimental literature

(2008) Kevin Jon Williams et al.   Nature clinical practice. Cardiovascular medicine

Notch signaling is activated by TLR stimulation and regulates macrophage functions

(2007) Tanapat Palaga et al.   EUROPEAN JOURNAL OF IMMUNOLOGY