Development and Optimization of an ELISA to Quantitate C3(H2O) as a Marker of Human Disease

Banff Lung Report: Current knowledge and future research perspectives for diagnosis and treatment of pulmonary antibody mediated rejection (AMR)

(2018) A Roux et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Complement system in lung transplantation

(2018) Hakim Azfar Ali et al.   CLINICAL TRANSPLANTATION

Intracellular C3 Protects Human Airway Epithelial Cells from Stress-Associated Cell Death

(2018) Hrishikesh S Kulkarni et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

(2018) Ben C. King et al.   Cell Metabolism

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

(2018) Giuseppina Arbore et al.   Nature Communications

A C3(H20) recycling pathway is a component of the intracellular complement system

(2017) Michelle Elvington et al.   JOURNAL OF CLINICAL INVESTIGATION

Complement’s hidden arsenal: New insights and novel functions inside the cell

(2017) M. Kathryn Liszewski et al.   MOLECULAR IMMUNOLOGY

Complement in clinical medicine: Clinical trials, case reports and therapy monitoring

(2017) Daniel Ricklin et al.   MOLECULAR IMMUNOLOGY

A novel “complement-metabolism-inflammasome axis” as a key regulator of immune cell effector function

(2016) Giuseppina Arbore et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation

(2016) Deborah J. Levine et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

CD46 Activation Regulates miR-150–Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+T Cells

(2016) Ben C. King et al.   JOURNAL OF IMMUNOLOGY

Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling

(2016) Zhuo A. Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

(2016) Katherine E. Lintner et al.   Frontiers in Immunology

Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome

(2015) E. C. Schramm et al.   BLOOD

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

(2015) Martin Kolev et al.   IMMUNITY

The complement system in systemic lupus erythematosus: an update

(2014) Jonatan Leffler et al.   ANNALS OF THE RHEUMATIC DISEASES

Intracellular sensing of complement C3 activates cell autonomous immunity

(2014) J. C. H. Tam et al.   SCIENCE

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

(2013) M. Kathryn Liszewski et al.   IMMUNITY

The tick-over theory revisited: Is C3 a contact-activated protein?

(2012) Bo Nilsson et al.   IMMUNOBIOLOGY

Pros and cons for C4d as a biomarker

(2012) Danielle Cohen et al.   KIDNEY INTERNATIONAL

Self-association and domain rearrangements between complement C3 and C3u provide insight into the activation mechanism of C3

(2010) Keying Li et al.   BIOCHEMICAL JOURNAL

Evidence for iC3 generation during cardiopulmonary bypass as the result of blood-gas interaction

(2010) M. PEKNA et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry

(2008) Michael C. Schuster et al.   MOLECULAR IMMUNOLOGY

Role of complement and complement regulators in the removal of apoptotic cells

(2007) L.A. Trouw et al.   MOLECULAR IMMUNOLOGY