Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

Complement and the Regulation of T Cell Responses

(2018) Erin E. West et al.   Annual Review of Immunology

CD46 is a potent co-stimulatory receptor for expansion of human IFN-γ-producing CD8 + T cells

(2018) Aida S. Hansen et al.   IMMUNOLOGY LETTERS

Complement in the fundamental processes of the cell

(2017) Owen A. Hawksworth et al.   MOLECULAR IMMUNOLOGY

Intracellular complement − the complosome − in immune cell regulation

(2017) Giuseppina Arbore et al.   MOLECULAR IMMUNOLOGY

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Keeping It All Going—Complement Meets Metabolism

(2017) Martin Kolev et al.   Frontiers in Immunology

Complement-Mediated Regulation of Metabolism and Basic Cellular Processes

(2016) Christoph Hess et al.   IMMUNITY

The “ins and outs” of complement-driven immune responses

(2016) Simon Freeley et al.   IMMUNOLOGICAL REVIEWS

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling

(2016) Daniel E Croker et al.   IMMUNOLOGY AND CELL BIOLOGY

TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells

(2016) Mana Furuoka et al.   JOURNAL OF CELLULAR PHYSIOLOGY

T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells

(2016) G. Arbore et al.   SCIENCE

Metabolic pathways in T cell activation and lineage differentiation

(2016) Luís Almeida et al.   SEMINARS IN IMMUNOLOGY

Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression

(2016) Y. Wang et al.   Cancer Discovery

Complement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell Responses

(2015) Martin Kolev et al.   IMMUNITY

NLRP3 at the interface of metabolism and inflammation

(2015) Moritz Haneklaus et al.   IMMUNOLOGICAL REVIEWS

The receptor NLRP3 is a transcriptional regulator of TH2 differentiation

(2015) Mélanie Bruchard et al.   NATURE IMMUNOLOGY

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Fatty acid metabolism in the regulation of T cell function

(2015) Matthias Lochner et al.   TRENDS IN IMMUNOLOGY

Human C3 Deficiency Associated with Impairments in Dendritic Cell Differentiation, Memory B Cells, and Regulatory T Cells

(2014) A. Ghannam et al.   JOURNAL OF IMMUNOLOGY

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation

(2013) M. Kathryn Liszewski et al.   IMMUNITY

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

(2013) Laura A. Sena et al.   IMMUNITY

CD46: The ‘multitasker’ of complement proteins

(2013) Hidekazu Yamamoto et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

The role of complement in CD4+ T cell homeostasis and effector functions

(2013) Martin Kolev et al.   SEMINARS IN IMMUNOLOGY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

The CD46-Jagged1 interaction is critical for human TH1 immunity

(2012) Gaëlle Le Friec et al.   NATURE IMMUNOLOGY

Calcitriol Modulates the CD46 Pathway in T Cells

(2012) Karoline Kickler et al.   PLoS One

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

(2010) John Cardone et al.   NATURE IMMUNOLOGY

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Effects of PI3K catalytic subunit and Akt isoform deficiency on mTOR and p70S6K activation in myoblasts

(2009) Ronald W. Matheny et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CD46-induced human Treg enhance B-cell responses

(2009) Anja Fuchs et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes

(2009) Helen J. Lachmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inherited Deficiency of Membrane Cofactor Protein Expression and Varying Manifestations of Recurrent Atypical Hemolytic Uremic Syndrome in a Sibling Pair

(2008) Lionel Couzi et al.   AMERICAN JOURNAL OF KIDNEY DISEASES