Sub-Chronic Microcystin-LR Liver Toxicity in Preexisting Diet-Induced Nonalcoholic Steatohepatitis in Rats

Nonalcoholic fatty liver disease alters microcystin-LR toxicokinetics and acute toxicity

(2019) John D. Clarke et al.   TOXICON

Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

(2018) David Højland Ipsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents

(2018) Leigh Goedeke et al.   HEPATOLOGY

CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis

(2018) Lei Zhao et al.   JOURNAL OF HEPATOLOGY

Warming Affects Growth Rates and Microcystin Production in Tropical Bloom-Forming Microcystis Strains

(2018) Trung Bui et al.   Toxins

Impairment of endoplasmic reticulum is involved in β-cell dysfunction induced by microcystin-LR

(2017) Yanyan Zhao et al.   ENVIRONMENTAL POLLUTION

Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase

(2017) Jinghui Liu et al.   ENVIRONMENTAL TOXICOLOGY

Serum microcystin levels positively linked with risk of hepatocellular carcinoma: A case-control study in southwest China

(2017) Chuanfen Zheng et al.   HEPATOLOGY

Upregulated absorption of dietary palmitic acids with changes in intestinal transporters in non-alcoholic steatohepatitis (NASH)

(2017) Hiroki Utsunomiya et al.   JOURNAL OF GASTROENTEROLOGY

Nonalcoholic Fatty Liver Disease Is a Susceptibility Factor for Perchloroethylene-Induced Liver Effects in Mice

(2017) Joseph A. Cichocki et al.   TOXICOLOGICAL SCIENCES

Association of MTTP gene variants with pediatric NAFLD: A candidate-gene-based analysis of single nucleotide variations in obese children

(2017) Dongling Dai et al.   PLoS One

Prolonged exposure to low-dose microcystin induces nonalcoholic steatohepatitis in mice: a systems toxicology study

(2016) Jun He et al.   ARCHIVES OF TOXICOLOGY

Is hepatic lipogenesis fundamental for NAFLD/NASH? A focus on the nuclear receptor coactivator PGC-1β

(2016) Simon Ducheix et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

First Identification of the Toxicity of Microcystins on Pancreatic Islet Function in Humans and the Involved Potential Biomarkers

(2016) Yanyan Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Microcystin-LR induces dysfunction of insulin secretion in rat insulinoma (INS-1) cells: Implications for diabetes mellitus

(2016) Yanyan Zhao et al.   JOURNAL OF HAZARDOUS MATERIALS

Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances

(2016) Jennie Ka Ching Lau et al.   JOURNAL OF PATHOLOGY

Non-alcoholic fatty liver disease and diabetes

(2016) Jonathan M. Hazlehurst et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Role of dietary fatty acids in liver injury caused by vinyl chloride metabolites in mice

(2016) Lisanne C Anders et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Role of Cholesterol in the Pathogenesis of NASH

(2016) George N. Ioannou   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis

(2015) BC Ferslew et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame

(2015) Samar H. Ibrahim et al.   DIGESTIVE DISEASES AND SCIENCES

Cyanobacteria blooms and non-alcoholic liver disease: evidence from a county level ecological study in the United States

(2015) Feng Zhang et al.   Environmental Health

Nonalcoholic steatohepatitis in precision medicine: Unraveling the factors that contribute to individual variability

(2015) John D. Clarke et al.   PHARMACOLOGY & THERAPEUTICS

Nonalcoholic fatty liver disease, metabolic risk factors, and hepatocellular carcinoma: An open question

(2015) Letiția Adela Maria Streba   WORLD JOURNAL OF GASTROENTEROLOGY

The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling

(2015) Jing Xu et al.   CELL CYCLE

Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease

(2015) Mariana Verdelho Machado et al.   PLoS One

Structure-Function of CD36 and Importance of Fatty Acid Signal Transduction in Fat Metabolism

(2014) Marta Yanina Pepino et al.   Annual Review of Nutrition

Free Fatty Acid Uptake in Humans With CD36 Deficiency

(2014) Kazanna C. Hames et al.   DIABETES

Synergistic interaction between genetics and disease on pravastatin disposition

(2014) John D. Clarke et al.   JOURNAL OF HEPATOLOGY

Selectivity and Potency of Microcystin Congeners against OATP1B1 and OATP1B3 Expressing Cancer Cells

(2014) Timo H. J. Niedermeyer et al.   PLoS One

Cholesterol-Induced Non-Alcoholic Fatty Liver Disease and Atherosclerosis Aggravated by Systemic Inflammation

(2014) Eung Ju Kim et al.   PLoS One

Identification of Environmental Chemicals Associated with the Development of Toxicant-associated Fatty Liver Disease in Rodents

(2014) Laila Al-Eryani et al.   TOXICOLOGIC PATHOLOGY

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

(2014) Banrida Wahlang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

State of knowledge and concerns on cyanobacterial blooms and cyanotoxins

(2013) Sylvain Merel et al.   ENVIRONMENT INTERNATIONAL

Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice

(2013) Banrida Wahlang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Environmental Toxin–Linked Nonalcoholic Steatohepatitis and Hepatic Metabolic Reprogramming in Obese Mice

(2013) Ratanesh Kumar Seth et al.   TOXICOLOGICAL SCIENCES

Microcystin-LR Exhibits Immunomodulatory Role in Mouse Primary Hepatocytes Through Activation of the NF-κB and MAPK Signaling Pathways

(2013) Jianying Zhang et al.   TOXICOLOGICAL SCIENCES

Spatial and thematic distribution of research on cyanotoxins

(2013) Sylvain Merel et al.   TOXICON

Biomarkers of prolonged exposure to microcystin-LR in mice

(2013) Daniela Sedan et al.   TOXICON

Hepatic fat loss in advanced nonalcoholic steatohepatitis: Are alterations in serum adiponectin the cause?

(2012) David van der Poorten et al.   HEPATOLOGY

Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by α4 Protein in HEK293 Cells

(2012) Tan Li et al.   International Journal of Biological Sciences

Toxicant-associated Steatohepatitis

(2012) Banrida Wahlang et al.   TOXICOLOGIC PATHOLOGY

Patients With NASH and Cryptogenic Cirrhosis Are Less Likely Than Those With Hepatitis C to Receive Liver Transplants

(2011) Jacqueline G. O'Leary et al.   Clinical Gastroenterology and Hepatology

Genomic Profiling of MicroRNAs and Proteomics Reveals an Early Molecular Alteration Associated with Tumorigenesis Induced by MC-LR in Mice

(2011) Yanyan Zhao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Evaluating Microcystin Exposure Risk through Fish Consumption

(2011) Amanda E. Poste et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

(2011) Yehuda Kamari et al.   JOURNAL OF HEPATOLOGY

Mechanisms of Lipotoxicity in NAFLD and Clinical Implications

(2011) Samar H Ibrahim et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Global warming and hepatotoxin production by cyanobacteria: What can we learn from experiments?

(2011) Rehab El-Shehawy et al.   WATER RESEARCH

Polychlorinated Biphenyls, Lead, and Mercury Are Associated with Liver Disease in American Adults: NHANES 2003–2004

(2010) Matt Cave et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection

(2010) Brad Q. Starley et al.   HEPATOLOGY

Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice

(2010) Jamil A Haque et al.   LABORATORY INVESTIGATION

Animal models of nonalcoholic fatty liver disease

(2010) Lionel Hebbard et al.   Nature Reviews Gastroenterology & Hepatology

Pro- and Anti-inflammatory Cytokines in Steatosis and Steatohepatitis

(2010) Fabiola Rabelo et al.   OBESITY SURGERY

Hepatic Lipid Partitioning and Liver Damage in Nonalcoholic Fatty Liver Disease

(2009) Zheng Zheng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Freshwater Cyanobacterial Blooms and Primary Liver Cancer Epidemiological Studies in Serbia

(2009) ZORICA SVIRČEV et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

First Identification of the Hepatotoxic Microcystins in the Serum of a Chronically Exposed Human Population Together with Indication of Hepatocellular Damage

(2009) Jun Chen et al.   TOXICOLOGICAL SCIENCES

Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition

(2009) Abigail Daily et al.   TOXICON

Alteration and recovery of the antioxidant system induced by sub-chronic exposure to microcystin-LR in mice: Its relation to liver lipid composition

(2009) Daniela Sedan et al.   TOXICON

Ultrastructural alteration of lymphocytes in spleen and pronephros of grass carp (Ctenopharyngodon idella) experimentally exposed to microcystin-LR

(2008) Li Li Wei et al.   AQUACULTURE

A review of cyanobacterial odorous and bioactive metabolites: Impacts and management alternatives in aquaculture

(2008) Juliette L. Smith et al.   AQUACULTURE

Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis

(2008) Angela A. Wendel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

ChREBP: A Glucose-activated Transcription Factor Involved in the Development of Metabolic Syndrome

(2008) Katsumi IIZUKA et al.   ENDOCRINE JOURNAL

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH

The use of total protein stains as loading controls: An alternative to high-abundance single-protein controls in semi-quantitative immunoblotting

(2008) Georgina M. Aldridge et al.   JOURNAL OF NEUROSCIENCE METHODS

Characterization of Organic Anion Transporting Polypeptide 1b2-null Mice: Essential Role in Hepatic Uptake/Toxicity of Phalloidin and Microcystin-LR

(2008) Hong Lu et al.   TOXICOLOGICAL SCIENCES

Hepatic recovery after damage produced by sub-chronic intoxication with the cyanotoxin microcystin LR

(2007) Darío Andrinolo et al.   TOXICON